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Toxin Exposure
0
Biomarker
Included in
Mercury, Blood
Baseline

Mercury is a naturally occurring heavy metal with no beneficial role in human biology.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
2,4-D
Baseline

2,4-Dichlorophenoxyacetic acid (2,4-D) is one of the most widely used herbicides, applied in agriculture and residential lawn treatments.

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3-Phenoxybenzoic Acid
Baseline

3-Phenoxybenzoic acid (3-PBA) is the primary urinary metabolite of pyrethroid insecticides, a large family of pesticides found in over 1,500 commercial products for agricultural, residential, and veterinary use.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Aflatoxin M1
Baseline

Aflatoxin M1 is formed in the body after ingesting aflatoxin B1, a mycotoxin produced by Aspergillus species that commonly contaminate corn, peanuts, grains, and spices.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Aluminum (Al)
Baseline

Aluminum is a common environmental metal with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Antimony (Sb)
Baseline

Antimony is a metalloid with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Arsenic (As)
Baseline

Arsenic is a naturally occurring metalloid found in soil, rock, and groundwater with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Atrazine Mercapturate
Baseline

Atrazine mercapturate is the primary urinary metabolite of atrazine, one of the most widely used herbicides in the US.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Barium (Ba)
Baseline

Barium is an alkaline earth metal found in soil, rock, and groundwater with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Beryllium (Be)
Baseline

Beryllium is a lightweight metal found in certain rocks and minerals with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Bismuth (Bi)
Baseline

Bismuth is a heavy metal considered relatively low in toxicity compared to other metals.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Bisphenol A (BPA)
Baseline

Bisphenol A (BPA) is a building block of polycarbonate plastics and epoxy resins found in food containers, water bottles, canned food linings, thermal receipts, and dental sealants.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Bisphenol S (BPS)
Baseline

Bisphenol S (BPS) is increasingly used as a BPA replacement in plastics, thermal paper, and consumer products marketed as "BPA-free.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Butylparaben
Baseline

Butyl-paraben is a synthetic preservative widely used in cosmetics, personal care products, pharmaceuticals, and some foods.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Cadmium (Cd)
Baseline

Cadmium is a persistent heavy metal with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Cesium (Cs)
Baseline

Cesium is an alkali metal found in soil and mineral deposits with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Chaetoglobosin A
Baseline

Chaetoglobosin A is a mold toxin produced by Chaetomium globosum, commonly found on damp drywall, wallpaper, plywood, and ceiling tiles in water-damaged buildings.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Diethylphosphate
Baseline

Diethylphosphate (DEP) is a metabolite of several organophosphate pesticides widely used in agriculture and residential pest control.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Citrinin (Dihydrocitrinone)
Baseline

Dihydrocitrinone is the primary urinary metabolite of the mycotoxin citrinin, produced by Penicillium and Aspergillus molds.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Diphenyl Phosphate
Baseline

Diphenyl phosphate (DPP) is the primary urinary metabolite of triphenyl phosphate, an organophosphate flame retardant used in plastics, electronics, nail polish, and furniture foam.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Enniatin B
Baseline

Enniatin B is a fat-soluble fungal toxin produced by Fusarium species that colonize moist cereals and plant foods including wheat, oats, maize, apples, coffee, and cocoa.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Ethylparaben
Baseline

Ethyl-paraben is a synthetic preservative widely used in cosmetics, toiletries, pharmaceuticals, and certain foods since the 1920s.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Gadolinium (Gd)
Baseline

Gadolinium is a rare earth metal with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Gliotoxin
Baseline

Gliotoxin is a highly bioactive mycotoxin produced primarily by Aspergillus fumigatus, commonly found in water-damaged buildings behind wallpaper, beneath flooring, and inside HVAC systems.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Glyphosate
Baseline

Glyphosate is the most widely used herbicide in the world, marketed as the active ingredient in Roundup.

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HEMA
Baseline

2-Hydroxyethyl mercapturic acid (HEMA) is the primary urinary metabolite of ethylene oxide, a highly reactive industrial gas classified as a known human carcinogen.

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Lead (Pb)
Baseline

Lead is one of the most persistent and biologically disruptive environmental toxins with no beneficial role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
MEOHP
Baseline

Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) is an oxidative metabolite of di-(2-ethylhexyl) phthalate (DEHP), one of the most widely produced plasticizers globally.

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Mercury (Hg)
Baseline

Mercury is one of the most biologically reactive metals humans commonly encounter.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Methylhippuric Acid
Baseline

Methylhippuric acids are the primary urinary metabolites of xylene, an aromatic hydrocarbon solvent used in printing, rubber, leather, and paint manufacturing.

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Methylparaben
Baseline

Methyl-paraben is the most commonly used paraben preservative due to its effectiveness and low cost.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Mono-2-ethylhexyl phthalate (MEHP)
Baseline

Mono-(2-ethylhexyl) phthalate (MEHP) is the primary active metabolite of DEHP, formed when this widespread plasticizer is absorbed and hydrolyzed in the body.

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Monobutyl phthalate (MBP)
Baseline

Monobutyl phthalate (MBP) is the primary metabolite of dibutyl phthalate (DBP), commonly found in PVC products, cosmetics, nail polish, and printing inks.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Monoethylphthalate (MEP)
Baseline

Monoethyl phthalate (MEP) is the primary metabolite of diethyl phthalate, a plasticizer and solvent used in personal care products, fragrances, and cosmetics.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Monoisobutyl phthalate (MiBP)
Baseline

Monoisobutyl phthalate (MiBP) is the primary metabolite of diisobutyl phthalate (DIBP), a plasticizer used in paints, printing inks, nail polish, and cosmetics.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Mycophenolic Acid
Baseline

Mycophenolic acid is an immunosuppressive fungal metabolite produced by Penicillium species found in water-damaged buildings and certain refrigerated or poorly stored foods.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
NACE
Baseline

N-acetyl (2-cyanoethyl) cysteine (NACE) is the major urinary metabolite of acrylonitrile, a possible human carcinogen used in production of acrylic fibers, resins, and rubber.

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NADB
Baseline

N-acetyl(3,4-dihydroxybutyl) cysteine (NADB) is a major metabolite of 1,3-butadiene, a known human carcinogen found in automobile exhaust, cigarette smoke, forest fires, and synthetic rubber production.

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NAE
Baseline

N-acetyl-S-(2-hydroxyethyl)-L-cysteine (NAE) is a urinary metabolite of vinyl chloride and other chlorinated solvents.

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NAP
Baseline

N-acetyl phenyl cysteine (NAP), also known as S-phenylmercapturic acid, is the most specific urinary biomarker of benzene exposure.

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NAPR
Baseline

N-acetyl (propyl) cysteine (NAPR) is a metabolite of 1-bromopropane, an organic solvent used for metal cleaning, foam gluing, and dry cleaning.

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Nickel (Ni)
Baseline

Nickel is a naturally occurring metal with no essential biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Ochratoxin A
Baseline

Ochratoxin A is a heat-stable mycotoxin produced by Aspergillus and Penicillium molds that colonize stored cereals, coffee beans, dried fruit, wine grapes, spices, and cocoa.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Oxybenzone
Baseline

Oxybenzone (benzophenone-3) is an ultraviolet filter found in 97% of Americans tested.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Palladium (Pd)
Baseline

Palladium is a platinum-group metal with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Perchlorate
Baseline

Perchlorate is a chemical that interferes with thyroid function by blocking iodide uptake into the thyroid gland.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Phenylglyoxylic Acid
Baseline

Phenylglyoxylic acid (PGO) is a urinary metabolite of styrene and ethylbenzene, volatile organic compounds found in plastics, resins, insulation materials, and tobacco smoke.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Platinum (Pt)
Baseline

Platinum is a noble metal found in trace amounts in the earth's crust with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Propylparaben
Baseline

Propyl-paraben is a synthetic preservative used in cosmetics, personal care products, pharmaceuticals, and packaged foods since the 1920s.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Roridin E
Baseline

Roridin E is a powerful mold toxin produced by fungi that grow on water-damaged building materials and on grains like corn, wheat, rye, and barley.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Sterigmatocystin
Baseline

Sterigmatocystin is a mold-derived toxin closely related to aflatoxin B1, produced by Aspergillus versicolor and other fungi that thrive in water-damaged buildings and on poorly stored foods.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Tellurium (Te)
Baseline

Tellurium is a metalloid with properties similar to sulfur and selenium but no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Thallium (Tl)
Baseline

Thallium is a highly toxic heavy metal historically known for use in rodenticides.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Thorium (Th)
Baseline

Thorium is a naturally occurring radioactive metal found in soil, rock, and mineral sands with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Tin (Sn)
Baseline

Tin is a naturally occurring metal with no essential biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Tungsten (W)
Baseline

Tungsten is a transition metal valued industrially for its hardness, heat resistance, and electrical properties.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Uranium (U)
Baseline

Uranium is a naturally occurring radioactive metal found in soil, rock, and groundwater with no biological role in humans.

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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Verrucarin A
Baseline

Verrucarin A is a highly toxic mold compound produced by Stachybotrys, Myrothecium, and Fusarium species that grow on water-damaged building materials and grains including corn, wheat, rye, and barley.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Zearalenone
Baseline

Zearalenone is a hormone-active mold toxin produced by Fusarium species that grow on grains in cool, damp conditions.

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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Thyroid Health
0
Biomarker
Included in
Albumin
Baseline

Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
DHEA-Sulfate (DHEA-S)
Baseline

DHEA-Sulfate (DHEA-S) is a steroid hormone that is made by the adrenal glands and converted into sex hormones such as estrogen and testosterone.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Triiodothyronine (T3)
Baseline

T4 and T3 are thyroid hormones that regulate the metabolism of the body.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Free Thyroxine Index
Baseline

The Free Thyroxine Index (FTI) is a calculated value that estimates the amount of unbound, biologically active thyroxine (free T4) circulating in your blood.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Selenium
Baseline

Selenium is an essential trace mineral that the body incorporates into more than 25 proteins called selenoproteins.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
T3 Uptake
Baseline

T3 Uptake (T3RU) is an indirect test that estimates how much of your thyroid-binding proteins - especially thyroxine-binding globulin (TBG) - are available to carry thyroid hormones in the blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
T4 (thyroxine) Total
Baseline

Thyroxine (T4) is one of the two main hormones produced by your thyroid gland (the other being triiodothyronine (T3)).

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Free Testosterone
Baseline

Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone, Bioavailable
Baseline

Bioavailable testosterone represents the fraction of testosterone in the blood that is readily available to tissues.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone, Total
Baseline

Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Thyroglobulin Antibodies
Baseline

Thyroglobulin antibodies (TgAb) are autoantibodies produced by the immune system that mistakenly target thyroglobulin, a large sugar-linked protein made by the thyroid gland.

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Thyroglobulin Antibodies (2)
Baseline

Thyroglobulin antibodies (TgAb) are autoantibodies produced by the immune system that mistakenly target thyroglobulin, a large sugar-linked protein made by the thyroid gland.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Thyroid Peroxidase (TPO) Ab
Baseline

Thyroid Peroxidase Antibodies (TPOAb) are a marker of the immune system attacking the thyroid gland.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Thyroid-Stimulating Hormone (TSH)
Baseline

TSH stands for thyroid stimulating hormone.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Sex Hormones
0
Biomarker
Included in
17-Hydroxyprogesterone
Baseline

17-Hydroxyprogesterone (17-OHP) is a steroid hormone that acts as an intermediate step in the production of other hormones.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Albumin
Baseline

Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Dihydrotestosterone
Baseline

Dihydrotestosterone (DHT) is a potent androgen formed primarily through the conversion of testosterone by the enzyme 5-alpha-reductase.

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DHEA-Sulfate (DHEA-S)
Baseline

DHEA-Sulfate (DHEA-S) is a steroid hormone that is made by the adrenal glands and converted into sex hormones such as estrogen and testosterone.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Estradiol
Baseline

Estradiol is the most potent form of estrogen, a hormone produced by both males and females, albeit in different amounts.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Follicle Stimulating Hormone (FSH)
Baseline

FSH is a hormone produced by the pituitary gland that helps the reproductive system develop eggs in women and sperm in men¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Free Androgen Index
Derived Biomarker
Baseline

The Free Androgen Index (FAI) is a calculated ratio used to estimate the amount of biologically active (free) testosterone circulating in the bloodstream.

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Method: Derived from laboratory results. If any input is measured by a laboratory-developed test (LDT) validated under CLIA, that input is not cleared or approved by the FDA. This ratio/index itself is not FDA-cleared. Results support clinician interpretation and are not a stand-alone diagnosis. Inputs: total testosterone, SHBG.
PSA Free
Baseline

Free PSA is the portion of PSA not bound to proteins.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
PSA % Free
Baseline

PSA % Free is the percentage of PSA not bound to proteins.

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Luteinizing hormone (LH)
Baseline

LH stands for luteinizing hormone, which is a hormone produced in the anterior pituitary gland involved in regulation of the reproductive function¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Anti-Mullerian Hormone
Baseline

Anti-Müllerian Hormone (AMH) is a protein hormone produced by the small, developing follicles in a woman’s ovaries.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Progesterone
Baseline

Progesterone is a hormone that plays an important role in your reproductive system.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Prolactin
Baseline

Prolactin is a hormone produced mainly by the pituitary gland, with smaller amounts made in the breast, uterus, brain, and immune system¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Psa Total
Baseline

PSA, or Prostate-Specific Antigen, is a protein primarily produced by prostate cells.

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Prostate Specific Antigen (PSA)
Baseline

PSA, or Prostate-Specific Antigen, is a protein primarily produced by prostate cells.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Sex Hormone Binding Globulin (SHBG)
Baseline

Sex Hormone Binding Globulin (SHBG) is a protein that is produced in the liver and binds to certain sex hormones, such as testosterone, estradiol, and dihydrotestosterone¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Free Testosterone
Baseline

Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone, Bioavailable
Baseline

Bioavailable testosterone represents the fraction of testosterone in the blood that is readily available to tissues.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone, Total
Baseline

Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone-to-Estradiol Ratio (T/E₂)
Derived Biomarker
Baseline

The Testosterone-to-Estradiol Ratio (T/E₂) reflects androgen–estrogen balance.

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Nutrients
0
Biomarker
Included in
Vitamin D
Baseline

Vitamin D is an essential and multifunctional micronutrient.

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Method: Usually performed by FDA-cleared immunoassay in CLIA-certified, CAP-accredited laboratories. If an LC/MS method is used at the performing site, the assay is a laboratory-developed test (LDT) validated under CLIA and not cleared or approved by the FDA. Results support clinician interpretation and are not a stand-alone diagnosis.
Vitamin C
Baseline

Vitamin C (also called L-ascorbic acid) is a water-soluble vitamin that you must obtain from diet, since unlike most animals we cannot make it ourselves.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Aspartate Aminotransferase (AST)
Baseline

Aspartate aminotransferase (AST) is an enzyme that helps break down amino acids and is found in various tissues, such as the liver, heart, muscles, kidneys, and brain.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Calcium
Baseline

Calcium is one of the most important and common minerals in your body.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Vitamin B12
Baseline

Vitamin B12 (cobalamin) is a water-soluble vitamin that plays a central role in energy production, DNA synthesis, red blood cell formation, and nervous system health.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Corrected Calcium (Albumin-adjusted)
Baseline

Corrected calcium is a calculated value that adjusts your measured total serum calcium based on your albumin level.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: total calcium, albumin.
High-sensitivity CRP
Baseline

High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.

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hsCRP-to-Albumin Ratio (CAR)
Baseline

The CRP-to-Albumin Ratio (CAR) integrates inflammation (CRP) with nutritional/hepatic reserve (albumin).

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Red Cell Dist Width (RDW)
Baseline

RDW is a measurement of the variability of red blood cell size.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Ferritin
Baseline

Ferritin is a blood protein that contains iron¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Folate (Folic Acid)
Baseline

Folate is a type of vitamin B that is essential for the production and maintenance of new cells, especially during periods of rapid growth, such as pregnancy, infancy, and adolescence.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
RBC Folate
Baseline

Red blood cell folate measures the concentration of folate stored inside red blood cells.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Hematocrit
Baseline

Hematocrit is a test that measures the proportion of blood volume occupied by red blood cells.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Hemoglobin
Baseline

Hemoglobin is a complex, iron-containing protein located within our red blood cells.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Homocysteine
Baseline

Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Total Iron Binding Capacity (TIBC)
Baseline

TIBC is a blood test that measures your blood's ability (capacity) to attach (bind) to iron and carry it throughout your body².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Iron
Baseline

Iron is a mineral that is essential for many biological processes in the body, such as oxygen transport, muscle activity, mitochondrial function, DNA synthesis, and sensing of hypoxia⁵.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Iron Saturation
Baseline

Iron saturation is a biomarker that measures the percentage of iron bound to transferrin, a protein that moves iron throughout the body¹.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Macrocytosis
Baseline

Macrocytosis refers to the presence of enlarged red blood cells (RBCs) - cells that have a higher-than-normal volume, typically defined as a mean corpuscular volume (MCV) greater than 100 fL.

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Magnesium RBC
Baseline

Magnesium is an essential mineral that acts as a cofactor for over 300 enzymatic reactions, including those that regulate energy production, DNA/RNA synthesis, protein formation, and nerve and muscle signaling.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Mean Cell Hemoglobin (MCH)
Baseline

MCH is the average mass of hemoglobin in a single red blood cell.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Mean Corpuscular Hemoglobin Concentration (MCHC)
Baseline

MCHC stands for mean corpuscular hemoglobin concentration.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Mean Cell Volume (MCV)
Baseline

MCV stands for mean corpuscular volume.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Microcytosis
Baseline

Microcytosis refers to the presence of small red blood cells (RBCs), typically defined by a low mean cell volume (MCV) - usually less than 80 fL.

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Vitamin K
Derived Biomarker
Baseline

Vitamin K is a fat-soluble vitamin required as a cofactor for enzymes that add carboxyl groups to specific proteins - a process known as γ-carboxylation.

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Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time. Derived from laboratory results. This score or index is not an FDA-cleared test. It aids clinician-directed assessment and is not a stand-alone diagnosis.
Platelet-to-WBC Ratio (PWR)
Derived Biomarker
Baseline

The Platelet-to-WBC Ratio (PWR) compares platelet counts with total white blood cell counts.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: platelets, WBC.
Vitamin B6
Baseline

Vitamin B6 (pyridoxine) is one of the essential B-vitamins, and it works in its active form called pyridoxal-5’-phosphate (PLP).

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Vitamin B6 (2)
Baseline

Vitamin B6 (pyridoxine) is one of the essential B-vitamins, and it works in its active form called pyridoxal-5’-phosphate (PLP).

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Red Blood Cells
Baseline

Red blood cells (RBCs), also known as erythrocytes, are the most abundant type of blood cells in your body.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
RDW MCV Ratio
Derived Biomarker
Baseline

The RDW/MCV ratio is a red blood cell metric that compares two distinct aspects of red cell morphology: - Red cell distribution width (RDW) which measures the *variation in size* among red blood cells in circulation.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: RDW, MCV.
Selenium
Baseline

Selenium is an essential trace mineral that the body incorporates into more than 25 proteins called selenoproteins.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Metabolic Health
0
Biomarker
Included in
Adiponectin
Baseline

Adiponectin is a protein hormone (also called an adipokine) that is mainly secreted by fat cells, but it is also produced in smaller amounts by muscle and the lining of blood vessels.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Alanine Aminotransferase (ALT)
Baseline

ALT is an enzyme that is mainly found in the liver cells and helps break down proteins and amino acids.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Apolipoprotein B
Baseline

Apolipoprotein B (ApoB) is a protein that has many functions in the body, such as transporting lipids (fats), regulating cholesterol metabolism, maintaining blood vessel integrity, and modulating immune responses¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Aspartate Aminotransferase (AST)
Baseline

Aspartate aminotransferase (AST) is an enzyme that helps break down amino acids and is found in various tissues, such as the liver, heart, muscles, kidneys, and brain.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Atherogenic Coefficient
Baseline

The Atherogenic Coefficient (AC) is a simple ratio that shows how much of your total cholesterol is made up of potentially harmful types - specifically, all cholesterol except HDL, the “good” cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Total-C, HDL-C.
Atherogenic Index of Plasma
Baseline

The Atherogenic Index of Plasma (AIP) is calculated as the logarithm of the ratio between triglycerides and HDL cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: TG, HDL-C.
Estim. Avg Glu (eAG)
Baseline

Hemoglobin A1c (HbA1c) reflects how much glucose (sugar) has become attached to your red blood cells over their 8–12 week lifespan.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Eag (mmol/l)
Baseline

Hemoglobin A1c (HbA1c) reflects how much glucose (sugar) has become attached to your red blood cells over their 8-12 week lifespan.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
C-Peptide
Baseline

C-peptide is a short protein fragment released by the pancreas every time it makes insulin.

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Castelli Risk Index I
Derived Biomarker
Baseline

The Castelli Risk Index I (CRI-I) is a cardiovascular risk marker calculated by dividing total cholesterol by HDL cholesterol.

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Castelli Risk Index II
Baseline

The Castelli Risk Index II (CRI-II) is a lipid ratio calculated by dividing LDL cholesterol (“bad” cholesterol) by HDL cholesterol (“good” cholesterol).

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Chloride
Baseline

Chloride is a type of electrolyte that carries an electric charge and helps control the amount of fluids and the balance of acids and bases (pH balance) in your body¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
HDL Cholesterol
Baseline

HDL cholesterol is a type of cholesterol that is carried by high-density lipoproteins (HDL) in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL Cholesterol
Baseline

LDL cholesterol is a type of cholesterol that is carried by low-density lipoproteins (LDL) in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL/HDL Ratio
Baseline

The LDL/HDL ratio shows the balance between 'bad' LDL cholesterol and 'good' HDL cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
VLDL Cholesterol
Baseline

VLDL cholesterol stands for very-low-density lipoprotein cholesterol.

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Cholesterol, Total
Baseline

Total cholesterol is a measure of the total amount of cholesterol in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Non-HDL Cholesterol
Baseline

Non-HDL cholesterol is a stronger predictor of cardiovascular risk than LDL alone, especially in contexts with elevated triglycerides.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Cholesterol/HDL Ratio
Baseline

The Total Cholesterol/HDL ratio measures the balance between all cholesterol in the blood and the 'good' HDL cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Carbon Dioxide, Total
Baseline

Total carbon dioxide (CO2) is a measure of the amount of carbon dioxide in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
High-sensitivity CRP
Baseline

High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.

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Fructosamine
Baseline

Fructosamine is a compound formed when glucose (sugar) in the blood attaches to proteins, mostly albumin.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
y-Glutamyl Transferase (GGT)
Baseline

γ-Glutamyl Transferase (GGT) is an enzyme primarily found in the liver, with elevated levels indicating potential liver dysfunction, oxidative stress, or cardiovascular risk¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Glucose
Baseline

Glucose is a type of sugar that is your body's main source of energy.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Hemoglobin A1c
Baseline

Hemoglobin A1c is a type of hemoglobin, which is the protein in your red blood cells that carries oxygen from your lungs to the rest of your body.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Homocysteine
Baseline

Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Insulin Fasting
Baseline

Fasting insulin reflects how much insulin the pancreas produces after an overnight fast.

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Insulin
Baseline

Insulin is a hormone that is produced by the pancreas and regulates the metabolism of glucose, fat and protein.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL-C to Apolipoprotein B Ratio (LDL-C/ApoB)
Derived Biomarker
Baseline

The LDL Cholesterol-to-Apolipoprotein B Ratio (LDL-C/ApoB) reflects cholesterol content per LDL particle and indicates LDL particle size/density.

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LDL Cholesterol / Total Cholesterol (Mass Ratio)
Baseline

The LDL / Total Cholesterol ratio is a simple calculation that expresses the proportion of total cholesterol that is made up of low-density lipoproteins (LDL), commonly referred to as “bad cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: LCL-C, Total Cholesterol.
Leptin
Baseline

Leptin is a hormone primarily produced by fat cells and released into the bloodstream in amounts that reflect the size of the body’s fat stores.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Neutrophil-to-HDL Cholesterol Ratio (NHR)
Derived Biomarker
Baseline

The Neutrophil-to-HDL Cholesterol Ratio (NHR) integrates innate immune activation (neutrophils) with HDL-C’s protective effects.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, HDL-C.
Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB)
Derived Biomarker
Baseline

The Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB) reflects cholesterol content per atherogenic particle across LDL, VLDL, IDL, and Lp(a).

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Non-HDL-C, ApoB.
NON-HDL Total Cholesterol Ratio
Derived Biomarker
Baseline

The Non-HDL / Total Cholesterol ratio measures the proportion of your total cholesterol that is carried by potentially harmful lipoproteins - all cholesterol excluding HDL, which is considered “good cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Non-HDL-C, Total-C.
Potassium
Baseline

Potassium is a mineral and an electrolyte that is critical for many body functions, including nerve signals, muscle contractions, heart rhythms, blood pressure, fluid balance, and pH balance¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Sodium
Baseline

Sodium is a mineral and an electrolyte that is essential for many body functions, including nerve signals, muscle contractions, fluid balance, blood pressure, and pH balance¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Triglyceride HDL Molar Ratio
Baseline

The Triglyceride / HDL Cholesterol ratio is a powerful marker of insulin resistance, metabolic syndrome, and cardiovascular risk.

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Triglycerides
Baseline

Triglycerides are a type of fat, or lipid, found in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB)
Derived Biomarker
Baseline

The Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB) estimates the triglyceride load per atherogenic particle.

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TyG Index
Baseline

The TyG Index is a metabolic risk marker calculated using fasting triglycerides and fasting glucose.

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Uric Acid
Baseline

Uric acid is a waste product that is formed when the body breaks down purines, which are chemicals found in some foods and drinks, such as red meat, organ meats, seafood, beer and fructose-sweetened beverages³.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Uric Acid-to-HDL Cholesterol Ratio (UHR)
Derived Biomarker
Baseline

The Uric Acid-to-HDL Cholesterol Ratio (UHR) integrates oxidative/inflammatory load (uric acid) with HDL’s vascular protection.

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Liver Health
0
Biomarker
Included in
Albumin/Globulin Ratio
Baseline

Globulin is a type of protein that is made by the liver and the immune system.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: albumin, globulin.
Albumin
Baseline

Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Alkaline Phosphatase (ALP)
Baseline

ALP is an enzyme that is found in various tissues, mainly in the liver and bone.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Alanine Aminotransferase (ALT)
Baseline

ALT is an enzyme that is mainly found in the liver cells and helps break down proteins and amino acids.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Aspartate Aminotransferase (AST)
Baseline

Aspartate aminotransferase (AST) is an enzyme that helps break down amino acids and is found in various tissues, such as the liver, heart, muscles, kidneys, and brain.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Bilirubin Direct
Baseline

Direct bilirubin (also known as conjugated bilirubin) is a water-soluble form of bilirubin that has been processed by the liver.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Bilirubin Indirect
Baseline

Indirect bilirubin (also known as unconjugated bilirubin) is a fat-soluble waste product generated during the normal breakdown of red blood cells, specifically from the heme component of hemoglobin.

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Bilirubin, Total
Baseline

Bilirubin is a yellowish pigment that is produced when red blood cells break down in the body.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Bilirubin-to-Albumin Ratio
Baseline

The Bilirubin-to-Albumin Ratio (B/A Ratio) integrates bilirubin production and albumin-bound clearance.

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Ferritin
Baseline

Ferritin is a blood protein that contains iron¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Ferritin-to-Albumin Ratio
Derived Biomarker
Baseline

The Ferritin-to-Albumin Ratio (FAR) integrates inflammation (ferritin) and nutritional status (albumin).

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: ferritin, albumin.
y-Glutamyl Transferase (GGT)
Baseline

γ-Glutamyl Transferase (GGT) is an enzyme primarily found in the liver, with elevated levels indicating potential liver dysfunction, oxidative stress, or cardiovascular risk¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
GGT-to-HDL Cholesterol Ratio
Baseline

The GGT-to-HDL Cholesterol Ratio (GGT/HDL-C) reflects oxidative stress versus lipid vascular protection.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Globulin, Total
Baseline

Globulin is a type of protein that is made by the liver and the immune system.

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Indirect-to-Direct Bilirubin Ratio
Derived Biomarker
Baseline

The Indirect-to-Direct Bilirubin Ratio (I/D Ratio) reflects bilirubin metabolism, conjugation, and clearance.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: indirect bilirubin, direct bilirubin.
Macrocytosis
Baseline

Macrocytosis refers to the presence of enlarged red blood cells (RBCs) - cells that have a higher-than-normal volume, typically defined as a mean corpuscular volume (MCV) greater than 100 fL.

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Microcytosis
Baseline

Microcytosis refers to the presence of small red blood cells (RBCs), typically defined by a low mean cell volume (MCV) - usually less than 80 fL.

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Protein, Total
Baseline

Total Protein measures the total amount of two classes of proteins found in the plasma: albumin and globulin.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Kidney Health
0
Biomarker
Included in
Albumin
Baseline

Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Appearance (Urine)
Baseline

Urine appearance describes the visual clarity of urine and reflects the presence or absence of suspended particles such as cells, bacteria, proteins, crystals, or mucus.

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Bacteria (Urine)
Baseline

Bacteria in urine sediment is measured by automated urinalysis, counting the number of bacteria per high power field.

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Bacteria (Urine) (2)
Baseline

Bacteria in urine sediment is checked by examining a urine sample under a microscope.

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Bilirubin (Urine)
Baseline

Urine bilirubin measures the presence of bilirubin, a yellow pigment produced from the breakdown of red blood cells, in the urine.

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Bilirubin (Urine) (2)
Baseline

Urine bilirubin measures the presence of bilirubin, a yellow pigment produced from the breakdown of red blood cells, in the urine.

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Calcium
Baseline

Calcium is one of the most important and common minerals in your body.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Character (Urine)
Baseline

Urine character describes the visual clarity of urine and reflects the presence or absence of suspended particles such as cells, bacteria, proteins, crystals, or mucus.

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Chloride
Baseline

Chloride is a type of electrolyte that carries an electric charge and helps control the amount of fluids and the balance of acids and bases (pH balance) in your body¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Color (Urine)
Baseline

Urine color is an indirect visual indicator of kidney function, fluid balance, and systemic metabolism.

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Color (Urine) (2)
Baseline

Urine color is an indirect visual indicator of kidney function, fluid balance, and systemic metabolism.

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Corrected Calcium (Albumin-adjusted)
Baseline

Corrected calcium is a calculated value that adjusts your measured total serum calcium based on your albumin level.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: total calcium, albumin.
Creatinine
Baseline

Creatinine is a waste product that comes from the normal wear and tear on muscles of the body³.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
hsCRP-to-Albumin Ratio (CAR)
Baseline

The CRP-to-Albumin Ratio (CAR) integrates inflammation (CRP) with nutritional/hepatic reserve (albumin).

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Crystals (Urine)
Baseline

Urine crystals are solid formations that can appear in urine sediment when certain dissolved substances precipitate out of solution.

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Asymmetric dimethylarginine (ADMA)
Baseline

Asymmetric dimethylarginine (ADMA) is a small molecule that comes from the normal breakdown of proteins in the body.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Symmetric dimethylarginine (SDMA)
Baseline

Symmetric dimethylarginine (SDMA) is a small molecule that comes from the natural breakdown of proteins in the body.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Epithelial Cast (Urine)
Baseline

Epithelial casts are cylindrical structures found in urine sediment that contain renal tubular epithelial cells trapped within a protein matrix.

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Epithelial Cells (Urine)
Baseline

Epithelial cells in urine sediment are counted by automated urinalysis.

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Renal Epithelial Cells (Urine)
Baseline

Renal epithelial cells are specialized cells that line the kidney tubules.

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Squamous Epithelial Cells (Urine)
Baseline

Squamous epithelial cells are flat cells that line the outer portion of the urinary tract and surrounding skin.

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Fatty Cast (Urine)
Baseline

Fatty casts are cylindrical structures found in urine sediment that contain lipid droplets or fat-laden cells within a protein matrix.

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Estimated Glomerular Filtration Rate (eGFR)
Baseline

Estimated glomerular filtration rate (eGFR) is a calculation that reflects how well the kidneys are functioning by estimating the volume of blood they filter each minute, adjusted to a standard body surface area (mL/min/1.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Globulin, Total
Baseline

Globulin is a type of protein that is made by the liver and the immune system.

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Glucose (Urine)
Baseline

Urine glucose measures the presence of glucose, the body's primary fuel derived from dietary carbohydrates, in the urine.

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Glucose (Urine) (2)
Baseline

Urine glucose measures the presence of glucose, the body's primary fuel derived from dietary carbohydrates, in the urine.

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Granular Cast (Urine)
Baseline

Granular casts are cylindrical structures found in urine sediment that contain granular material from degenerating cells or aggregated proteins.

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Occult Blood (Urine)
Baseline

Urine occult blood measures the presence of red blood cells or hemoglobin in the urine that may be invisible to the naked eye.

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Occult Blood (Urine) (2)
Baseline

Urine occult blood measures the presence of red blood cells or hemoglobin in the urine that may be invisible to the naked eye.

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Hyaline Cast (Urine)
Baseline

Hyaline casts are cylindrical protein structures formed in the kidney tubules and detected in urine by automated urinalysis.

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Ketones Confirmation (Urine)
Baseline

Urine ketone confirmation (Acetest) is a follow-up test that confirms the presence of ketone bodies using a different analytical method than the initial dipstick screening.

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Ketones (Urine)
Baseline

Urine ketones measure the presence of ketone bodies, which are byproducts of fat metabolism produced when the body uses fat instead of glucose as its primary energy source.

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Ketones (Urine) (2)
Baseline

Urine ketones measure the presence of ketone bodies, which are byproducts of fat metabolism produced when the body uses fat instead of glucose as its primary energy source.

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Leukocyte Esterase (Urine)
Baseline

Urine leukocyte esterase measures the presence of esterase, an enzyme released by activated white blood cells (neutrophils) in the urinary tract.

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Leukocyte Esterase (Urine) (2)
Baseline

Urine leukocyte esterase measures the presence of esterase, an enzyme released by activated white blood cells (leukocytes) involved in immune defense.

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Nitrite (Urine)
Baseline

Urine nitrite measures the presence of nitrites formed when certain bacteria convert naturally occurring urinary nitrates into nitrites.

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Nitrite (Urine) (2)
Baseline

Urine nitrite measures the presence of nitrites formed when certain bacteria convert naturally occurring urinary nitrates into nitrites.

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pH (Urine)
Baseline

Urine pH measures the acidity or alkalinity of urine and reflects the body's regulation of acid-base balance through the kidneys.

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pH (Urine) (2)
Baseline

Urine pH measures the acidity or alkalinity of urine and reflects the body's regulation of acid-base balance through the kidneys.

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Potassium
Baseline

Potassium is a mineral and an electrolyte that is critical for many body functions, including nerve signals, muscle contractions, heart rhythms, blood pressure, fluid balance, and pH balance¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Protein, Total
Baseline

Total Protein measures the total amount of two classes of proteins found in the plasma: albumin and globulin.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Protein (Urine)
Baseline

Urine protein measures the presence of protein in the urine and reflects the integrity of the kidney's filtration barrier.

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Protein (Urine) (2)
Baseline

Urine protein measures the presence of protein in the urine and reflects the integrity of the kidney's filtration barrier.

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RBC (Urine)
Baseline

Urinary red blood cells (RBCs) measure the presence of intact red blood cells detected by automated urinalysis.

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RBC Cast (Urine)
Baseline

Red blood cell (RBC) casts are cylindrical structures found in urine sediment that contain intact red blood cells trapped within a protein matrix.

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RBC (Urine) (2)
Baseline

Urinary red blood cells (RBCs) measure the presence of intact red blood cells detected by urine microscopy.

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Reducing Substances (Urine)
Baseline

Urine reducing substances (Clinitest) measures the presence of reducing sugars and other reducing compounds in urine using a chemical reaction method.

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Sodium
Baseline

Sodium is a mineral and an electrolyte that is essential for many body functions, including nerve signals, muscle contractions, fluid balance, blood pressure, and pH balance¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Specific Gravity (Urine)
Baseline

Urine specific gravity measures the concentration of dissolved particles in urine relative to pure water and reflects the kidneys' ability to regulate fluid balance by concentrating or diluting urine.

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Specific Gravity (Urine) (2)
Baseline

Urine specific gravity measures the concentration of dissolved particles in urine relative to pure water and reflects the kidneys' ability to regulate fluid balance by concentrating or diluting urine.

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Sperm Cells (Urine)
Baseline

Spermatozoa in urine are detected by automated urinalysis and indicate the presence of sperm cells in the urine sample.

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Trichomonas (Urine)
Baseline

Trichomonas detection in urine identifies the presence of Trichomonas vaginalis, a parasitic protozoan that causes trichomoniasis, a common sexually transmitted infection.

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Uric Acid
Baseline

Uric acid is a waste product that is formed when the body breaks down purines, which are chemicals found in some foods and drinks, such as red meat, organ meats, seafood, beer and fructose-sweetened beverages³.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
BUN/Creatinine Ratio
Derived Biomarker
Baseline

BUN/Creatinine ratio is a calculation that compares the levels of blood urea nitrogen (BUN) and creatinine in your blood.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Blood Urea Nitrogen (BUN)
Baseline

BUN stands for blood urea nitrogen, which is a waste product that is produced when your body breaks down the protein in the foods you eat.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Urea-to-Creatinine Ratio
Baseline

The Urea-to-Creatinine Ratio (UCR) provides insight into renal stress, hydration, protein metabolism, and pre-renal vs.

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Uric Acid-to-HDL Cholesterol Ratio (UHR)
Derived Biomarker
Baseline

The Uric Acid-to-HDL Cholesterol Ratio (UHR) integrates oxidative/inflammatory load (uric acid) with HDL’s vascular protection.

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Urobilinogen (Urine)
Baseline

Urine urobilinogen measures the concentration of urobilinogen, a byproduct of bilirubin metabolism produced by intestinal bacteria.

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Waxy Cast (Urine)
Baseline

Waxy casts are cylindrical structures found in urine sediment with a smooth, waxy appearance.

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WBC (Urine)
Baseline

Urine white blood cells (WBCs) measure the presence of immune cells in the urine and indicate inflammatory activity within the urinary tract.

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WBC Cast (Urine)
Baseline

White blood cell (WBC) casts are cylindrical structures found in urine sediment that contain white blood cells trapped within a protein matrix.

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WBC (Urine) (2)
Baseline

Urine white blood cells (WBCs) measure the presence of immune cells in the urine and indicate inflammatory activity within the urinary tract.

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Yeast (Urine)
Baseline

Yeast cells in urine are detected by automated urinalysis and indicate the presence of fungal organisms, most commonly Candida species.

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Inflammation
0
Biomarker
Included in
High-sensitivity CRP
Baseline

High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.

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hsCRP-to-Albumin Ratio (CAR)
Baseline

The CRP-to-Albumin Ratio (CAR) integrates inflammation (CRP) with nutritional/hepatic reserve (albumin).

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Erythrocyte Sedimentation Rate
Baseline

Erythrocyte sedimentation rate (ESR), or sedimentation rate measures how quickly erythrocytes (red blood cells) settle at the bottom of a test tube over a period of one hour.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Ferritin
Baseline

Ferritin is a blood protein that contains iron¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Ferritin-to-Albumin Ratio
Derived Biomarker
Baseline

The Ferritin-to-Albumin Ratio (FAR) integrates inflammation (ferritin) and nutritional status (albumin).

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: ferritin, albumin.
Lymphocyte-to-Monocyte Ratio (LMR)
Derived Biomarker
Baseline

The Lymphocyte-to-Monocyte Ratio (LMR) reflects the balance between adaptive immune function (lymphocytes) and innate immune activation (monocytes).

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: lymphocytes, monocytes.
Monocyte-to-HDL Ratio (MHR)
Derived Biomarker
Baseline

The Monocyte-to-HDL Ratio (MHR) reflects the balance between inflammation and cardiovascular protection.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: monocytes, HDL-C.
Monocyte-to-Lymphocyte Ratio (MLR)
Derived Biomarker
Baseline

The Monocyte-to-Lymphocyte Ratio (MLR) captures the balance between innate inflammatory processes (monocytes) and adaptive immune response (lymphocytes).

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: monocytes, lymphocytes.
Neutrophil-to-HDL Cholesterol Ratio (NHR)
Derived Biomarker
Baseline

The Neutrophil-to-HDL Cholesterol Ratio (NHR) integrates innate immune activation (neutrophils) with HDL-C’s protective effects.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, HDL-C.
Neutrophil-to-Lymphocyte-Platelet Ratio (NLPR)
Derived Biomarker
Baseline

The Neutrophil-to-(Lymphocyte × Platelet) Ratio (NLPR) combines neutrophils, lymphocytes, and platelets to reflect inflammatory burden, adaptive immunity, and repair capacity.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, lymphocytes, platelets.
Neutrophil-to-Lymphocyte Ratio (NLR)
Derived Biomarker
Baseline

The Neutrophil-to-Lymphocyte Ratio (NLR) reflects balance between innate and adaptive immunity.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, lymphocytes.
Platelet-to-Lymphocyte Ratio (PLR)
Derived Biomarker
Baseline

The Platelet-to-Lymphocyte Ratio (PLR) reflects thrombo-inflammatory burden and immune balance by combining platelet activity with adaptive immune status.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: platelets, lymphocytes.
Platelet-to-WBC Ratio (PWR)
Derived Biomarker
Baseline

The Platelet-to-WBC Ratio (PWR) compares platelet counts with total white blood cell counts.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: platelets, WBC.
Rheumatoid Arthritis Factor (RF)
Baseline

Rheumatoid factor (RF) is an autoantibody - an antibody directed against the body’s own tissues rather than foreign invaders.

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Systemic Immune-Inflammation Index
Baseline

The Systemic Immune-Inflammation Index (SII) integrates platelets, neutrophils, and lymphocytes.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: CBC differentials.
Systemic Inflammation Response Index (SIRI)
Baseline

The Systemic Inflammation Response Index (SIRI) = (neutrophils × monocytes) / lymphocytes, integrating innate inflammatory activity with adaptive immune regulation.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, monocytes, lymphocytes.
White Blood Cells
Baseline

WBCs are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders³.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Immune System
0
Biomarker
Included in
Alternaria alternata (m6) IgE
Baseline

Alternaria alternata IgE measures your immune system's specific allergic antibody response to spores produced by Alternaria alternata, one of the most common outdoor molds worldwide.

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Aspergillus fumigatus (m3) IgE
Baseline

Aspergillus fumigatus IgE measures your immune system's specific allergic antibody response to spores produced by Aspergillus fumigatus, a common environmental mold found in soil, decaying organic matter, compost, and indoor environments with moisture problems.

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D. farinae (d2) IgE
Baseline

Dermatophagoides farinae IgE measures your immune system's specific allergic antibody response to proteins produced by the American house dust mite.

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Bands
Baseline

Bands (or band neutrophils) are immature white blood cells that develop into fully functional neutrophils - key players in the body’s innate immune system, which serves as the first line of defense against infection.

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Basophils
Baseline

Basophils are a type of white blood cell that the bone marrow makes.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Baso (Absolute)
Baseline

Basophils are a type of white blood cell that are part of the immune system.

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Bermuda Grass (g2) IgE
Baseline

Bermuda grass IgE measures your immune system's specific allergic antibody response to proteins found in Bermuda grass pollen.

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Absolute Blast Count
Baseline

Absolute Blast Count measures the actual number of blast cells - very immature blood cells circulating in the bloodstream.

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Burr Cells
Baseline

Burr cells, also known as echinocytes (or “hedgehog cells”), are red blood cells with a spiky or serrated outer surface, giving them a thorny appearance that contrasts with the smooth, disc-shaped profile of healthy red blood cells.

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Cat Dander (e1) IgE
Baseline

Cat dander IgE measures your immune system's specific allergic antibody response to proteins produced by cats — primarily Fel d 1, which is found in cat skin flakes (dander), saliva, and urine.

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Cockroach (i6) IgE
Baseline

Cockroach IgE measures your immune system's specific allergic antibody response to proteins found in cockroach saliva, droppings, shed body parts, and decomposing remains.

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Rough Pigweed (w14) IgE
Baseline

Rough pigweed IgE measures your immune system's specific allergic antibody response to proteins found in rough pigweed pollen.

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Common Ragweed (w1) IgE
Baseline

Common ragweed IgE measures your immune system's specific allergic antibody response to proteins found in short ragweed pollen.

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High-sensitivity CRP
Baseline

High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.

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Cyclic Citrullinated Peptide Antibody
Baseline

Cyclic Citrullinated Peptide (CCP) antibodies are autoantibodies that target proteins in the body that have undergone a process called citrullination.

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Cyclic Citrullinated Peptide Antibody (2)
Baseline

Cyclic Citrullinated Peptide (CCP) antibodies are autoantibodies that target proteins in the body that have undergone a process called citrullination.

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Double-stranded DNA Antibodies
Baseline

Double-stranded DNA (dsDNA) antibodies are autoantibodies that target the body’s own genetic material - specifically, the double-helix structure of DNA inside the cell nucleus.

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Dog Dander (e5) IgE
Baseline

Dog dander IgE measures your immune system's specific allergic antibody response to proteins produced by dogs — primarily Can f 1, found in dog dander, saliva, and urine.

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Eosinophils
Baseline

Eosinophils are a type of white blood cell that are part of the immune system².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Eos (Absolute)
Baseline

Eosinophils are a type of white blood cell and a component of the immune system, playing a crucial role in the body's defense against parasitic infections, allergens, and in mediating allergic reactions.

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Erythrocyte Sedimentation Rate
Baseline

Erythrocyte sedimentation rate (ESR), or sedimentation rate measures how quickly erythrocytes (red blood cells) settle at the bottom of a test tube over a period of one hour.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
D. pteronyssinus (d1) IgE
Baseline

Dermatophagoides pteronyssinus IgE measures your immune system's specific allergic antibody response to proteins produced by the European house dust mite.

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Ferritin
Baseline

Ferritin is a blood protein that contains iron¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Immunoglobulin A
Baseline

Immunoglobulin A (IgA) is one of the body’s main types of antibodies and plays a central role in the immune defenses that protect the body’s mucosal surfaces — the thin, moist linings of the gut, airways, mouth, and eyes.

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Immunoglobulin E
Baseline

Immunoglobulin E

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Sycamore (t11) IgE
Baseline

Sycamore IgE measures your immune system's specific allergic antibody response to proteins found in sycamore tree pollen.

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Lymphocytes
Baseline

Lymphocytes are a type of white blood cell that are part of the immune system.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Lymphs (Absolute)
Baseline

Lymphocytes are a type of white blood cell that are integral to the immune system.

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Metamyelocyte
Baseline

Metamyelocytes are immature granulocytes normally absent in healthy peripheral blood.

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Monocytes
Baseline

Monocytes are a type of white blood cell that are produced in the bone marrow and then enter the bloodstream⁴.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Monocytes (Absolute)
Baseline

Monocytes are a type of white blood cell that are part of the immune system.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Atypical Mononuclear Cells
Baseline

Mononuclear cells are a group of white blood cells characterized by having a single, round nucleus.

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Mountain Cedar (t6) IgE
Baseline

Mountain cedar IgE measures your immune system's specific allergic antibody response to proteins found in mountain cedar pollen.

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Mugwort (w6) IgE
Baseline

Mugwort IgE measures your immune system's specific allergic antibody response to proteins found in mugwort pollen.

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Neutrophils
Baseline

Neutrophils are a type of white blood cell and the most abundant type of granulocytes in the bloodstream, playing a crucial role in the body's first line of defense against infection.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Neutrophils (Absolute)
Baseline

Neutrophils are a type of white blood cell and the most abundant type of granulocytes in the bloodstream, playing a crucial role in the body's first line of defense against infection.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Antinuclear Antibodies (ANA) (2)
Baseline

The Antinuclear Antibody (ANA) screen is a broad test that looks for antibodies directed against the nucleus of your own cells.

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Penicillium notatum (m1) IgE
Baseline

Penicillium notatum IgE measures your immune system's specific allergic antibody response to spores and proteins produced by Penicillium notatum (now known as Penicillium chrysogenum), a common indoor and outdoor mold.

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Mean Platelet Volume (MPV)
Baseline

Mean Platelet Volume (MPV) measures the average size of your platelets - the small cell fragments in your blood that help with clotting, wound repair, and inflammation control.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Mean Platelet Volume
Baseline

Mean Platelet Volume (MPV) measures the average size of your platelets - the small cell fragments in your blood that help with clotting, wound repair, and inflammation control.

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Platelet Count
Baseline

Platelets are tiny components of your blood that help with clotting.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Prolymphocytes
Baseline

Prolymphocytes are immature lymphocytes which are developing cells on their way to becoming fully functional B-cells or T-cells, which are central to your body’s adaptive immune system.

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Promyelocytes
Baseline

Promyelocytes are immature white blood cells that belong to the granulocyte lineage - the family of immune cells that includes neutrophils, eosinophils, and basophils.

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Rheumatoid Factor
Baseline

Rheumatoid factor (RF) is an autoantibody - an antibody directed against the body’s own tissues rather than foreign invaders.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Birch (t3) IgE
Baseline

Birch IgE measures your immune system's specific allergic antibody response to proteins found in birch tree pollen.

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Anti-SS-A 52kD Ab
Baseline

Sjogren’s Antibody (SS-A, also called Ro) is an autoantibody that targets proteins bound to RNA inside the nucleus and cytoplasm.

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Anti-Ro (SS-A) Ab
Baseline

Anti-SSA 60 (Ro60) is one of the two main subtypes of SS-A antibodies (the other being SSA 52).

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Sjogren's Antibody (SS-B)
Baseline

Sjogren’s Antibody (SS-B, also called La) is an autoantibody that targets the La protein, a nuclear protein involved in stabilizing RNA molecules and assisting with their proper processing.

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Smith Antibody
Baseline

Smith (Sm) antibodies are autoantibodies - antibodies that mistakenly target the body’s own cells rather than external threats like bacteria or viruses.

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Timothy Grass (g6) IgE
Baseline

Timothy grass IgE measures your immune system's specific allergic antibody response to proteins found in Timothy grass pollen.

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RNP Antibody
Baseline

RNP antibodies are autoantibodies directed against ribonucleoproteins, molecules made of RNA and proteins that are essential for normal cell function.

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Atypical Lymphs
Baseline

Atypical lymphocytes - also called reactive lymphocytes - are white blood cells that appear larger and more irregular than typical lymphocytes when viewed under a microscope.

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White Blood Cells
Baseline

WBCs are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders³.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
White Ash (t15) IgE
Baseline

White ash IgE measures your immune system's specific allergic antibody response to proteins found in white ash tree pollen.

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Elm (t8) IgE
Baseline

Elm IgE measures your immune system's specific allergic antibody response to proteins found in elm tree pollen.

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White Mulberry (t70) IgE
Baseline

White mulberry IgE measures your immune system's specific allergic antibody response to proteins found in white mulberry tree pollen.

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Oak (t7) IgE
Baseline

Oak IgE measures your immune system's specific allergic antibody response to proteins found in oak tree pollen.

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Heart & Vascular Health
0
Biomarker
Included in
Apolipoprotein B
Baseline

Apolipoprotein B (ApoB) is a protein that has many functions in the body, such as transporting lipids (fats), regulating cholesterol metabolism, maintaining blood vessel integrity, and modulating immune responses¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Atherogenic Coefficient
Baseline

The Atherogenic Coefficient (AC) is a simple ratio that shows how much of your total cholesterol is made up of potentially harmful types - specifically, all cholesterol except HDL, the “good” cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Total-C, HDL-C.
Atherogenic Index of Plasma
Baseline

The Atherogenic Index of Plasma (AIP) is calculated as the logarithm of the ratio between triglycerides and HDL cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: TG, HDL-C.
Castelli Risk Index I
Derived Biomarker
Baseline

The Castelli Risk Index I (CRI-I) is a cardiovascular risk marker calculated by dividing total cholesterol by HDL cholesterol.

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Castelli Risk Index II
Baseline

The Castelli Risk Index II (CRI-II) is a lipid ratio calculated by dividing LDL cholesterol (“bad” cholesterol) by HDL cholesterol (“good” cholesterol).

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HDL Cholesterol
Baseline

HDL cholesterol is a type of cholesterol that is carried by high-density lipoproteins (HDL) in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL Cholesterol
Baseline

LDL cholesterol is a type of cholesterol that is carried by low-density lipoproteins (LDL) in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL/HDL Ratio
Baseline

The LDL/HDL ratio shows the balance between 'bad' LDL cholesterol and 'good' HDL cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
VLDL Cholesterol
Baseline

VLDL cholesterol stands for very-low-density lipoprotein cholesterol.

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Cholesterol, Total
Baseline

Total cholesterol is a measure of the total amount of cholesterol in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Non-HDL Cholesterol
Baseline

Non-HDL cholesterol is a stronger predictor of cardiovascular risk than LDL alone, especially in contexts with elevated triglycerides.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Cholesterol/HDL Ratio
Baseline

The Total Cholesterol/HDL ratio measures the balance between all cholesterol in the blood and the 'good' HDL cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Carbon Dioxide, Total
Baseline

Total carbon dioxide (CO2) is a measure of the amount of carbon dioxide in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
High-sensitivity CRP
Baseline

High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.

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hsCRP-to-Albumin Ratio (CAR)
Baseline

The CRP-to-Albumin Ratio (CAR) integrates inflammation (CRP) with nutritional/hepatic reserve (albumin).

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Asymmetric dimethylarginine (ADMA)
Baseline

Asymmetric dimethylarginine (ADMA) is a small molecule that comes from the normal breakdown of proteins in the body.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Symmetric dimethylarginine (SDMA)
Baseline

Symmetric dimethylarginine (SDMA) is a small molecule that comes from the natural breakdown of proteins in the body.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
GGT-to-HDL Cholesterol Ratio
Baseline

The GGT-to-HDL Cholesterol Ratio (GGT/HDL-C) reflects oxidative stress versus lipid vascular protection.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Homocysteine
Baseline

Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL-C to Apolipoprotein B Ratio (LDL-C/ApoB)
Derived Biomarker
Baseline

The LDL Cholesterol-to-Apolipoprotein B Ratio (LDL-C/ApoB) reflects cholesterol content per LDL particle and indicates LDL particle size/density.

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Oxidized LDL
Baseline

Oxidized LDL (oxLDL) measures the amount of low-density lipoprotein cholesterol that has undergone oxidative modification.

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LDL Cholesterol / Total Cholesterol (Mass Ratio)
Baseline

The LDL / Total Cholesterol ratio is a simple calculation that expresses the proportion of total cholesterol that is made up of low-density lipoproteins (LDL), commonly referred to as “bad cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: LCL-C, Total Cholesterol.
Lipoprotein (a)
Baseline

Lipoprotein (a) or Lp(a) is a macromolecular complex composed of one molecule of Low-Density Lipoprotein (LDL) containing apolipoprotein B100 and one molecule of apolipoprotein(a)¹.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Monocyte-to-HDL Ratio (MHR)
Derived Biomarker
Baseline

The Monocyte-to-HDL Ratio (MHR) reflects the balance between inflammation and cardiovascular protection.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: monocytes, HDL-C.
Neutrophil-to-HDL Cholesterol Ratio (NHR)
Derived Biomarker
Baseline

The Neutrophil-to-HDL Cholesterol Ratio (NHR) integrates innate immune activation (neutrophils) with HDL-C’s protective effects.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, HDL-C.
Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB)
Derived Biomarker
Baseline

The Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB) reflects cholesterol content per atherogenic particle across LDL, VLDL, IDL, and Lp(a).

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Non-HDL-C, ApoB.
NON-HDL Total Cholesterol Ratio
Derived Biomarker
Baseline

The Non-HDL / Total Cholesterol ratio measures the proportion of your total cholesterol that is carried by potentially harmful lipoproteins - all cholesterol excluding HDL, which is considered “good cholesterol.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Non-HDL-C, Total-C.
Triglyceride HDL Molar Ratio
Baseline

The Triglyceride / HDL Cholesterol ratio is a powerful marker of insulin resistance, metabolic syndrome, and cardiovascular risk.

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Triglycerides
Baseline

Triglycerides are a type of fat, or lipid, found in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB)
Derived Biomarker
Baseline

The Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB) estimates the triglyceride load per atherogenic particle.

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TyG Index
Baseline

The TyG Index is a metabolic risk marker calculated using fasting triglycerides and fasting glucose.

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Uric Acid
Baseline

Uric acid is a waste product that is formed when the body breaks down purines, which are chemicals found in some foods and drinks, such as red meat, organ meats, seafood, beer and fructose-sweetened beverages³.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Gut Health
0
Biomarker
Included in
Albumin/Globulin Ratio
Baseline

Globulin is a type of protein that is made by the liver and the immune system.

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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: albumin, globulin.
Albumin
Baseline

Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Bilirubin-to-Albumin Ratio
Baseline

The Bilirubin-to-Albumin Ratio (B/A Ratio) integrates bilirubin production and albumin-bound clearance.

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Globulin, Total
Baseline

Globulin is a type of protein that is made by the liver and the immune system.

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Protein, Total
Baseline

Total Protein measures the total amount of two classes of proteins found in the plasma: albumin and globulin.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Tissue Transglutaminase Ab
Baseline

Tissue Transglutaminase Antibody, IgA (tTG-IgA), is an autoantibody produced when the immune system reacts abnormally to gluten - a protein found in wheat, barley, and rye.

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Tissue Transglutaminase Ab (2)
Baseline

Tissue Transglutaminase Antibody, IgA (tTG-IgA), is an autoantibody produced when the immune system reacts abnormally to gluten - a protein found in wheat, barley, and rye.

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Energy
0
Biomarker
Included in
Aspartate Aminotransferase (AST)
Baseline

Aspartate aminotransferase (AST) is an enzyme that helps break down amino acids and is found in various tissues, such as the liver, heart, muscles, kidneys, and brain.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Carbon Dioxide, Total
Baseline

Total carbon dioxide (CO2) is a measure of the amount of carbon dioxide in your blood.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Cortisol (2)
Baseline

Cortisol is a hormone made by the adrenal glands that helps you respond to stress and regulate various bodily functions.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
DHEA-Sulfate (DHEA-S)
Baseline

DHEA-Sulfate (DHEA-S) is a steroid hormone that is made by the adrenal glands and converted into sex hormones such as estrogen and testosterone.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Insulin-like Growth Factor 1 (IGF-1)
Baseline

Insulin-like Growth Factor-1 (IGF-1) is a hormone similar in molecular structure to insulin¹.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Z Score
Baseline

The IGF-1 Z Score is the number of standard deviations an IGF-1 result is above or below the age- and sex-matched population mean (SD units).

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Testosterone-to-Estradiol Ratio (T/E₂)
Derived Biomarker
Baseline

The Testosterone-to-Estradiol Ratio (T/E₂) reflects androgen–estrogen balance.

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DNA Health
0
Biomarker
Included in
Vitamin B12
Baseline

Vitamin B12 (cobalamin) is a water-soluble vitamin that plays a central role in energy production, DNA synthesis, red blood cell formation, and nervous system health.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Ferritin
Baseline

Ferritin is a blood protein that contains iron¹².

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Folate (Folic Acid)
Baseline

Folate is a type of vitamin B that is essential for the production and maintenance of new cells, especially during periods of rapid growth, such as pregnancy, infancy, and adolescence.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
RBC Folate
Baseline

Red blood cell folate measures the concentration of folate stored inside red blood cells.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Homocysteine
Baseline

Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Iron
Baseline

Iron is a mineral that is essential for many biological processes in the body, such as oxygen transport, muscle activity, mitochondrial function, DNA synthesis, and sensing of hypoxia⁵.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Methylmalonic Acid
Baseline

Methylmalonic acid (MMA) is a small organic acid that builds up when the body cannot properly use vitamin B12 (cobalamin).

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Vitamin B6
Baseline

Vitamin B6 (pyridoxine) is one of the essential B-vitamins, and it works in its active form called pyridoxal-5’-phosphate (PLP).

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Vitamin B6 (2)
Baseline

Vitamin B6 (pyridoxine) is one of the essential B-vitamins, and it works in its active form called pyridoxal-5’-phosphate (PLP).

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Brain Health
0
Biomarker
Included in
Vitamin D
Baseline

Vitamin D is an essential and multifunctional micronutrient.

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Method: Usually performed by FDA-cleared immunoassay in CLIA-certified, CAP-accredited laboratories. If an LC/MS method is used at the performing site, the assay is a laboratory-developed test (LDT) validated under CLIA and not cleared or approved by the FDA. Results support clinician interpretation and are not a stand-alone diagnosis.
Vitamin B12
Baseline

Vitamin B12 (cobalamin) is a water-soluble vitamin that plays a central role in energy production, DNA synthesis, red blood cell formation, and nervous system health.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Cortisol (2)
Baseline

Cortisol is a hormone made by the adrenal glands that helps you respond to stress and regulate various bodily functions.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
High-sensitivity CRP
Baseline

High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.

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Estradiol
Baseline

Estradiol is the most potent form of estrogen, a hormone produced by both males and females, albeit in different amounts.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Folate (Folic Acid)
Baseline

Folate is a type of vitamin B that is essential for the production and maintenance of new cells, especially during periods of rapid growth, such as pregnancy, infancy, and adolescence.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Triiodothyronine (T3)
Baseline

T4 and T3 are thyroid hormones that regulate the metabolism of the body.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Homocysteine
Baseline

Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Insulin-like Growth Factor 1 (IGF-1)
Baseline

Insulin-like Growth Factor-1 (IGF-1) is a hormone similar in molecular structure to insulin¹.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Insulin Fasting
Baseline

Fasting insulin reflects how much insulin the pancreas produces after an overnight fast.

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Insulin
Baseline

Insulin is a hormone that is produced by the pancreas and regulates the metabolism of glucose, fat and protein.

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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Free Testosterone
Baseline

Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone, Bioavailable
Baseline

Bioavailable testosterone represents the fraction of testosterone in the blood that is readily available to tissues.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone, Total
Baseline

Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.

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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Derived Biomarkers
Like all comprehensive health platforms, Superpower provides derived biomarkers. Derived biomarkers are standard clinical tools used by healthcare providers worldwide.

A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.

The following biomarkers Progesterone, Vitamin K, ADMA/SDMA, IGF-1, Thyroid Peroxidase, Lipoprotein Fractionation, NMR and Thyroglobulin Antibody are not currently offered for Superpower members residing in New York/New Jersey. Some methods are laboratory-developed tests (LDTs) validated under CLIA but not cleared or approved by the U.S. FDA. Public claims mirror the performing laboratory’s intended-use language. Clinicians interpret results in context and may order confirmatory testing where appropriate.

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What is biomarker testing?

At Superpower, biomarker testing is the foundation of everything we do. It’s not about guesswork, quick fixes, or “one-size-fits-all” health advice. It’s about data.

Biomarker testing measures the actual molecules in your blood, saliva, or other samples that reflect how your body is working at the deepest level.

These results are then mapped against optimal ranges so you can see where you stand — today, not years later when problems surface.

Why testing matters

  • Detect early signs of conditions including cardiovascular disease, metabolic dysfunction, and hormonal imbalance to increase the chance for intervention and potential outcomes.
  • Understand your health baseline to improve your energy, metabolism, and longevity, particularly by tracking related biomarkers over time.
  • Monitor health changes in response to new diet, exercise, or supplement regimens, helping to objectively measure the impact of lifestyle adjustments.
  • Personalize your health decisions, including assessing your risks and protocol options, rather than relying on average population data or standard guidelines alone.

FAQs

Biomarker testing is a laboratory analysis of genes, proteins, hormones, or other molecules in your blood or tissues to help assess your health, identify risk factors, or guide personalized care decisions. To learn more, read ourguides on biomarker testing.

Biomarker testing can identify hidden health risks, nutritional deficiencies, hormone levels, or early signs of disease — allowing for targeted lifestyle or medical interventions before symptoms develop. To learn more, read our guides on specificillnesses and diseasesthat biomarker testing can assist with.

People interested in optimizing health, longevity, or athletic performance, men and women monitoring hormone status (including testosterone), or those with specific health concerns (like heart, thyroid, or metabolic health) all benefit from biomarker testing.

Our biomarker tests at Superpower require a simple blood draw — either at home or in a clinic. Some other tests use additional samples like urine or saliva, depending on what is being measured.

Yes, certain biomarkers are linked to risks for cardiovascular disease, diabetes, hormone imbalances, metabolic syndrome, and even some cancers, enabling early and personalized prevention strategies.

For most people, testing every 6–12 months is recommended for ongoing monitoring and tracking changes in health or the effectiveness of interventions, though frequency can vary based on goals and medical advice.

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