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Mercury is a naturally occurring heavy metal with no beneficial role in human biology.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Mercury is a metal that can be found in different forms in the environment and in some products.
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2,4-Dichlorophenoxyacetic acid (2,4-D) is one of the most widely used herbicides, applied in agriculture and residential lawn treatments.
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3-Phenoxybenzoic acid (3-PBA) is the primary urinary metabolite of pyrethroid insecticides, a large family of pesticides found in over 1,500 commercial products for agricultural, residential, and veterinary use.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Aflatoxin M1 is formed in the body after ingesting aflatoxin B1, a mycotoxin produced by Aspergillus species that commonly contaminate corn, peanuts, grains, and spices.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Aluminum is a common environmental metal with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Antimony is a metalloid with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Arsenic is a naturally occurring metalloid found in soil, rock, and groundwater with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Atrazine mercapturate is the primary urinary metabolite of atrazine, one of the most widely used herbicides in the US.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Barium is an alkaline earth metal found in soil, rock, and groundwater with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Beryllium is a lightweight metal found in certain rocks and minerals with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Bismuth is a heavy metal considered relatively low in toxicity compared to other metals.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Bisphenol A (BPA) is a building block of polycarbonate plastics and epoxy resins found in food containers, water bottles, canned food linings, thermal receipts, and dental sealants.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Bisphenol S (BPS) is increasingly used as a BPA replacement in plastics, thermal paper, and consumer products marketed as "BPA-free.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Butyl-paraben is a synthetic preservative widely used in cosmetics, personal care products, pharmaceuticals, and some foods.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Cadmium is a persistent heavy metal with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Cesium is an alkali metal found in soil and mineral deposits with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Chaetoglobosin A is a mold toxin produced by Chaetomium globosum, commonly found on damp drywall, wallpaper, plywood, and ceiling tiles in water-damaged buildings.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Diethylphosphate (DEP) is a metabolite of several organophosphate pesticides widely used in agriculture and residential pest control.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Dihydrocitrinone is the primary urinary metabolite of the mycotoxin citrinin, produced by Penicillium and Aspergillus molds.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Diphenyl phosphate (DPP) is the primary urinary metabolite of triphenyl phosphate, an organophosphate flame retardant used in plastics, electronics, nail polish, and furniture foam.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Enniatin B is a fat-soluble fungal toxin produced by Fusarium species that colonize moist cereals and plant foods including wheat, oats, maize, apples, coffee, and cocoa.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Ethyl-paraben is a synthetic preservative widely used in cosmetics, toiletries, pharmaceuticals, and certain foods since the 1920s.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Gadolinium is a rare earth metal with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Gliotoxin is a highly bioactive mycotoxin produced primarily by Aspergillus fumigatus, commonly found in water-damaged buildings behind wallpaper, beneath flooring, and inside HVAC systems.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Glyphosate is the most widely used herbicide in the world, marketed as the active ingredient in Roundup.
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2-Hydroxyethyl mercapturic acid (HEMA) is the primary urinary metabolite of ethylene oxide, a highly reactive industrial gas classified as a known human carcinogen.
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Lead is one of the most persistent and biologically disruptive environmental toxins with no beneficial role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) is an oxidative metabolite of di-(2-ethylhexyl) phthalate (DEHP), one of the most widely produced plasticizers globally.
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Mercury is one of the most biologically reactive metals humans commonly encounter.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Methylhippuric acids are the primary urinary metabolites of xylene, an aromatic hydrocarbon solvent used in printing, rubber, leather, and paint manufacturing.
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Methyl-paraben is the most commonly used paraben preservative due to its effectiveness and low cost.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Mono-(2-ethylhexyl) phthalate (MEHP) is the primary active metabolite of DEHP, formed when this widespread plasticizer is absorbed and hydrolyzed in the body.
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Monobutyl phthalate (MBP) is the primary metabolite of dibutyl phthalate (DBP), commonly found in PVC products, cosmetics, nail polish, and printing inks.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Monoethyl phthalate (MEP) is the primary metabolite of diethyl phthalate, a plasticizer and solvent used in personal care products, fragrances, and cosmetics.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Monoisobutyl phthalate (MiBP) is the primary metabolite of diisobutyl phthalate (DIBP), a plasticizer used in paints, printing inks, nail polish, and cosmetics.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Mycophenolic acid is an immunosuppressive fungal metabolite produced by Penicillium species found in water-damaged buildings and certain refrigerated or poorly stored foods.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
N-acetyl (2-cyanoethyl) cysteine (NACE) is the major urinary metabolite of acrylonitrile, a possible human carcinogen used in production of acrylic fibers, resins, and rubber.
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N-acetyl(3,4-dihydroxybutyl) cysteine (NADB) is a major metabolite of 1,3-butadiene, a known human carcinogen found in automobile exhaust, cigarette smoke, forest fires, and synthetic rubber production.
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N-acetyl-S-(2-hydroxyethyl)-L-cysteine (NAE) is a urinary metabolite of vinyl chloride and other chlorinated solvents.
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N-acetyl phenyl cysteine (NAP), also known as S-phenylmercapturic acid, is the most specific urinary biomarker of benzene exposure.
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N-acetyl (propyl) cysteine (NAPR) is a metabolite of 1-bromopropane, an organic solvent used for metal cleaning, foam gluing, and dry cleaning.
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Nickel is a naturally occurring metal with no essential biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Ochratoxin A is a heat-stable mycotoxin produced by Aspergillus and Penicillium molds that colonize stored cereals, coffee beans, dried fruit, wine grapes, spices, and cocoa.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Oxybenzone (benzophenone-3) is an ultraviolet filter found in 97% of Americans tested.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Palladium is a platinum-group metal with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Perchlorate is a chemical that interferes with thyroid function by blocking iodide uptake into the thyroid gland.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Phenylglyoxylic acid (PGO) is a urinary metabolite of styrene and ethylbenzene, volatile organic compounds found in plastics, resins, insulation materials, and tobacco smoke.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Platinum is a noble metal found in trace amounts in the earth's crust with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Propyl-paraben is a synthetic preservative used in cosmetics, personal care products, pharmaceuticals, and packaged foods since the 1920s.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 17D0919496); not cleared or approved by the FDA. Results reported in µg/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Roridin E is a powerful mold toxin produced by fungi that grow on water-damaged building materials and on grains like corn, wheat, rye, and barley.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Sterigmatocystin is a mold-derived toxin closely related to aflatoxin B1, produced by Aspergillus versicolor and other fungi that thrive in water-damaged buildings and on poorly stored foods.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Tellurium is a metalloid with properties similar to sulfur and selenium but no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Thallium is a highly toxic heavy metal historically known for use in rodenticides.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Thorium is a naturally occurring radioactive metal found in soil, rock, and mineral sands with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Tin is a naturally occurring metal with no essential biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Tungsten is a transition metal valued industrially for its hardness, heat resistance, and electrical properties.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Uranium is a naturally occurring radioactive metal found in soil, rock, and groundwater with no biological role in humans.
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Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
Verrucarin A is a highly toxic mold compound produced by Stachybotrys, Myrothecium, and Fusarium species that grow on water-damaged building materials and grains including corn, wheat, rye, and barley.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Zearalenone is a hormone-active mold toxin produced by Fusarium species that grow on grains in cool, damp conditions.
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Method: LC-MS/MS (Liquid Chromatography/Tandem Mass Spectrometry) measuring free (unconjugated) mycotoxins in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in ng/g creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
DHEA-Sulfate (DHEA-S) is a steroid hormone that is made by the adrenal glands and converted into sex hormones such as estrogen and testosterone.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
T4 and T3 are thyroid hormones that regulate the metabolism of the body.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Free Thyroxine Index (FTI) is a calculated value that estimates the amount of unbound, biologically active thyroxine (free T4) circulating in your blood.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
T4 and T3 are thyroid hormones that regulate the metabolism of the body.
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Selenium is an essential trace mineral that the body incorporates into more than 25 proteins called selenoproteins.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
T3 Uptake (T3RU) is an indirect test that estimates how much of your thyroid-binding proteins - especially thyroxine-binding globulin (TBG) - are available to carry thyroid hormones in the blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Thyroxine (T4) is one of the two main hormones produced by your thyroid gland (the other being triiodothyronine (T3)).
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Bioavailable testosterone represents the fraction of testosterone in the blood that is readily available to tissues.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Thyroglobulin antibodies (TgAb) are autoantibodies produced by the immune system that mistakenly target thyroglobulin, a large sugar-linked protein made by the thyroid gland.
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Thyroglobulin antibodies (TgAb) are autoantibodies produced by the immune system that mistakenly target thyroglobulin, a large sugar-linked protein made by the thyroid gland.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Thyroid Peroxidase Antibodies (TPOAb) are a marker of the immune system attacking the thyroid gland.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
TSH stands for thyroid stimulating hormone.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
17-Hydroxyprogesterone (17-OHP) is a steroid hormone that acts as an intermediate step in the production of other hormones.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Dihydrotestosterone (DHT) is a potent androgen formed primarily through the conversion of testosterone by the enzyme 5-alpha-reductase.
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DHEA-Sulfate (DHEA-S) is a steroid hormone that is made by the adrenal glands and converted into sex hormones such as estrogen and testosterone.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Estradiol is the most potent form of estrogen, a hormone produced by both males and females, albeit in different amounts.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
FSH is a hormone produced by the pituitary gland that helps the reproductive system develop eggs in women and sperm in men¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Free Androgen Index (FAI) is a calculated ratio used to estimate the amount of biologically active (free) testosterone circulating in the bloodstream.
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Method: Derived from laboratory results. If any input is measured by a laboratory-developed test (LDT) validated under CLIA, that input is not cleared or approved by the FDA. This ratio/index itself is not FDA-cleared. Results support clinician interpretation and are not a stand-alone diagnosis. Inputs: total testosterone, SHBG.
Free PSA is the portion of PSA not bound to proteins.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
PSA % Free is the percentage of PSA not bound to proteins.
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LH stands for luteinizing hormone, which is a hormone produced in the anterior pituitary gland involved in regulation of the reproductive function¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Anti-Müllerian Hormone (AMH) is a protein hormone produced by the small, developing follicles in a woman’s ovaries.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Progesterone is a hormone that plays an important role in your reproductive system.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Prolactin is a hormone produced mainly by the pituitary gland, with smaller amounts made in the breast, uterus, brain, and immune system¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
PSA, or Prostate-Specific Antigen, is a protein primarily produced by prostate cells.
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PSA, or Prostate-Specific Antigen, is a protein primarily produced by prostate cells.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Sex Hormone Binding Globulin (SHBG) is a protein that is produced in the liver and binds to certain sex hormones, such as testosterone, estradiol, and dihydrotestosterone¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Bioavailable testosterone represents the fraction of testosterone in the blood that is readily available to tissues.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
The Testosterone-to-Estradiol Ratio (T/E₂) reflects androgen–estrogen balance.
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Vitamin D is an essential and multifunctional micronutrient.
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Method: Usually performed by FDA-cleared immunoassay in CLIA-certified, CAP-accredited laboratories. If an LC/MS method is used at the performing site, the assay is a laboratory-developed test (LDT) validated under CLIA and not cleared or approved by the FDA. Results support clinician interpretation and are not a stand-alone diagnosis.
Arachidonic acid is a polyunsaturated omega-6 fatty acid found in the phospholipids of the body’s cells.
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The arachidonic acid/EPA ratio is a marker of the balance between omega-6 (pro-inflammatory) and omega-3 (anti-inflammatory) fatty acids in the body.
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Vitamin C (also called L-ascorbic acid) is a water-soluble vitamin that you must obtain from diet, since unlike most animals we cannot make it ourselves.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Aspartate aminotransferase (AST) is an enzyme that helps break down amino acids and is found in various tissues, such as the liver, heart, muscles, kidneys, and brain.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Calcium is one of the most important and common minerals in your body.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Vitamin B12 (cobalamin) is a water-soluble vitamin that plays a central role in energy production, DNA synthesis, red blood cell formation, and nervous system health.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Corrected calcium is a calculated value that adjusts your measured total serum calcium based on your albumin level.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: total calcium, albumin.
High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.
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The CRP-to-Albumin Ratio (CAR) integrates inflammation (CRP) with nutritional/hepatic reserve (albumin).
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DHA (docosahexaenoic acid) is a long chain omega-3 fatty acid that is the primary omega-3 fatty acid found in the central nervous system where it plays both a structural and functional role in cells².
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DPA (docosapentaenoic acid) is a long chain omega-3 fatty acid.
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EPA (eicosapentaenoic acid) is a long chain omega-3 fatty acid that is found along with DHA (docosahexaenoic acid) in cold-water fish, such as tuna and salmon⁴ and is also synthesized in the body from ALA (alpha-linolenic acid), the essential omega-3 fatty acid⁴.
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RDW is a measurement of the variability of red blood cell size.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Ferritin is a blood protein that contains iron¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Folate is a type of vitamin B that is essential for the production and maintenance of new cells, especially during periods of rapid growth, such as pregnancy, infancy, and adolescence.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Red blood cell folate measures the concentration of folate stored inside red blood cells.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Hematocrit is a test that measures the proportion of blood volume occupied by red blood cells.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Hemoglobin is a complex, iron-containing protein located within our red blood cells.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
TIBC is a blood test that measures your blood's ability (capacity) to attach (bind) to iron and carry it throughout your body².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
UIBC is a blood test that measures how much transferrin in your blood is not yet bound to iron¹.
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Iron is a mineral that is essential for many biological processes in the body, such as oxygen transport, muscle activity, mitochondrial function, DNA synthesis, and sensing of hypoxia⁵.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Iron saturation is a biomarker that measures the percentage of iron bound to transferrin, a protein that moves iron throughout the body¹.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Linoleic acid is a polyunsaturated omega-6 fatty acid that's essential for human health.
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Macrocytosis refers to the presence of enlarged red blood cells (RBCs) - cells that have a higher-than-normal volume, typically defined as a mean corpuscular volume (MCV) greater than 100 fL.
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Magnesium is an essential mineral that acts as a cofactor for over 300 enzymatic reactions, including those that regulate energy production, DNA/RNA synthesis, protein formation, and nerve and muscle signaling.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
MCH is the average mass of hemoglobin in a single red blood cell.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
MCHC stands for mean corpuscular hemoglobin concentration.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
MCV stands for mean corpuscular volume.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Microcytosis refers to the presence of small red blood cells (RBCs), typically defined by a low mean cell volume (MCV) - usually less than 80 fL.
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Omega-3 total refers to the combined amount of omega-3 fatty acids (EPA, DPA, DHA, and others) in the body.
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The omega-6/omega-3 ratio is a measure of the balance between these two types of fatty acids in the body.
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Omega-6 total measures the combined amount of omega-6 fatty acids in the body which includes Arachidonic Acid and Linoleic Acid.
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Vitamin K is a fat-soluble vitamin required as a cofactor for enzymes that add carboxyl groups to specific proteins - a process known as γ-carboxylation.
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Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time. Derived from laboratory results. This score or index is not an FDA-cleared test. It aids clinician-directed assessment and is not a stand-alone diagnosis.
The Platelet-to-WBC Ratio (PWR) compares platelet counts with total white blood cell counts.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: platelets, WBC.
Vitamin B6 (pyridoxine) is one of the essential B-vitamins, and it works in its active form called pyridoxal-5’-phosphate (PLP).
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Vitamin B6 (pyridoxine) is one of the essential B-vitamins, and it works in its active form called pyridoxal-5’-phosphate (PLP).
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Red blood cells (RBCs), also known as erythrocytes, are the most abundant type of blood cells in your body.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The RDW/MCV ratio is a red blood cell metric that compares two distinct aspects of red cell morphology:
- Red cell distribution width (RDW) which measures the *variation in size* among red blood cells in circulation.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: RDW, MCV.
Vitamin A is a fat-soluble vitamin essential for vision, immune defense, reproduction, and tissue growth.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Vitamin B2 (riboflavin) is a water-soluble vitamin that serves as the building block for two key coenzymes: flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
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Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time. Derived from laboratory results. This score or index is not an FDA-cleared test. It aids clinician-directed assessment and is not a stand-alone diagnosis.
Vitamin B2 (riboflavin) is a water-soluble vitamin that serves as the building block for two key coenzymes: flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
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Selenium is an essential trace mineral that the body incorporates into more than 25 proteins called selenoproteins.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Zinc is an essential micronutrient integral to numerous biological processes in the human body.
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Adiponectin is a protein hormone (also called an adipokine) that is mainly secreted by fat cells, but it is also produced in smaller amounts by muscle and the lining of blood vessels.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
ALT is an enzyme that is mainly found in the liver cells and helps break down proteins and amino acids.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Apolipoprotein B (ApoB) is a protein that has many functions in the body, such as transporting lipids (fats), regulating cholesterol metabolism, maintaining blood vessel integrity, and modulating immune responses¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Aspartate aminotransferase (AST) is an enzyme that helps break down amino acids and is found in various tissues, such as the liver, heart, muscles, kidneys, and brain.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Atherogenic Coefficient (AC) is a simple ratio that shows how much of your total cholesterol is made up of potentially harmful types - specifically, all cholesterol except HDL, the “good” cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Total-C, HDL-C.
The Atherogenic Index of Plasma (AIP) is calculated as the logarithm of the ratio between triglycerides and HDL cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: TG, HDL-C.
Hemoglobin A1c (HbA1c) reflects how much glucose (sugar) has become attached to your red blood cells over their 8–12 week lifespan.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Hemoglobin A1c (HbA1c) reflects how much glucose (sugar) has become attached to your red blood cells over their 8-12 week lifespan.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Body Mass Index (BMI) is a simple calculation using height and weight to estimate body fat.
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C-peptide is a short protein fragment released by the pancreas every time it makes insulin.
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The Castelli Risk Index I (CRI-I) is a cardiovascular risk marker calculated by dividing total cholesterol by HDL cholesterol.
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The Castelli Risk Index II (CRI-II) is a lipid ratio calculated by dividing LDL cholesterol (“bad” cholesterol) by HDL cholesterol (“good” cholesterol).
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Chloride is a type of electrolyte that carries an electric charge and helps control the amount of fluids and the balance of acids and bases (pH balance) in your body¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
HDL cholesterol is a type of cholesterol that is carried by high-density lipoproteins (HDL) in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL cholesterol is a type of cholesterol that is carried by low-density lipoproteins (LDL) in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The LDL/HDL ratio shows the balance between 'bad' LDL cholesterol and 'good' HDL cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
LDL size refers to the average diameter of low-density lipoprotein (LDL) particles circulating in the bloodstream.
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VLDL cholesterol stands for very-low-density lipoprotein cholesterol.
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Total cholesterol is a measure of the total amount of cholesterol in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Non-HDL cholesterol is a stronger predictor of cardiovascular risk than LDL alone, especially in contexts with elevated triglycerides.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Total Cholesterol/HDL ratio measures the balance between all cholesterol in the blood and the 'good' HDL cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Total carbon dioxide (CO2) is a measure of the amount of carbon dioxide in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.
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Fructosamine is a compound formed when glucose (sugar) in the blood attaches to proteins, mostly albumin.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
γ-Glutamyl Transferase (GGT) is an enzyme primarily found in the liver, with elevated levels indicating potential liver dysfunction, oxidative stress, or cardiovascular risk¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Glucose is a type of sugar that is your body's main source of energy.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Fasting plasma glucose measures the concentration of glucose in the blood after a period of no caloric intake (typically 8–12 hours).
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Hemoglobin A1c is a type of hemoglobin, which is the protein in your red blood cells that carries oxygen from your lungs to the rest of your body.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Insulin is a hormone made by the pancreas that helps move glucose from the bloodstream into cells, where it can be used for energy or stored for later, while also regulating fat and protein metabolism.
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Fasting insulin reflects how much insulin the pancreas produces after an overnight fast.
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Insulin is a hormone that is produced by the pancreas and regulates the metabolism of glucose, fat and protein.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The CardioIQ Insulin Resistance Score is a composite test that combines measurements of intact insulin and C-peptide measured using a very sensitive technique called liquid chromatography–tandem mass spectrometry (LC/MS/MS).
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The LDL Cholesterol-to-Apolipoprotein B Ratio (LDL-C/ApoB) reflects cholesterol content per LDL particle and indicates LDL particle size/density.
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The LDL / Total Cholesterol ratio is a simple calculation that expresses the proportion of total cholesterol that is made up of low-density lipoproteins (LDL), commonly referred to as “bad cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: LCL-C, Total Cholesterol.
Leptin is a hormone primarily produced by fat cells and released into the bloodstream in amounts that reflect the size of the body’s fat stores.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
The LP-IR Score (Lipoprotein Insulin Resistance Score) is a composite metric derived from six advanced lipoprotein markers measured by nuclear magnetic resonance (NMR) spectroscopy.
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VLDL Size is the average diameter of very-low-density lipoprotein (VLDL) particles in your bloodstream, typically measured in nanometers (nm) using nuclear magnetic resonance (NMR) spectroscopy.
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Large VLDL-P measures the concentration of the largest, triglyceride-rich very-low-density lipoprotein (VLDL) particles in circulation.
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The Neutrophil-to-HDL Cholesterol Ratio (NHR) integrates innate immune activation (neutrophils) with HDL-C’s protective effects.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, HDL-C.
The Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB) reflects cholesterol content per atherogenic particle across LDL, VLDL, IDL, and Lp(a).
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Non-HDL-C, ApoB.
The Non-HDL / Total Cholesterol ratio measures the proportion of your total cholesterol that is carried by potentially harmful lipoproteins - all cholesterol excluding HDL, which is considered “good cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Non-HDL-C, Total-C.
Measures how efficiently your body manages energy, blood sugar, and fat metabolism.
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Potassium is a mineral and an electrolyte that is critical for many body functions, including nerve signals, muscle contractions, heart rhythms, blood pressure, fluid balance, and pH balance¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Sodium is a mineral and an electrolyte that is essential for many body functions, including nerve signals, muscle contractions, fluid balance, blood pressure, and pH balance¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Triglyceride / HDL Cholesterol ratio is a powerful marker of insulin resistance, metabolic syndrome, and cardiovascular risk.
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Triglycerides are a type of fat, or lipid, found in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB) estimates the triglyceride load per atherogenic particle.
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The TyG Index is a metabolic risk marker calculated using fasting triglycerides and fasting glucose.
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Uric acid is a waste product that is formed when the body breaks down purines, which are chemicals found in some foods and drinks, such as red meat, organ meats, seafood, beer and fructose-sweetened beverages³.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Uric Acid-to-HDL Cholesterol Ratio (UHR) integrates oxidative/inflammatory load (uric acid) with HDL’s vascular protection.
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Globulin is a type of protein that is made by the liver and the immune system.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: albumin, globulin.
Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
ALP is an enzyme that is found in various tissues, mainly in the liver and bone.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
ALT is an enzyme that is mainly found in the liver cells and helps break down proteins and amino acids.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Aspartate aminotransferase (AST) is an enzyme that helps break down amino acids and is found in various tissues, such as the liver, heart, muscles, kidneys, and brain.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Direct bilirubin (also known as conjugated bilirubin) is a water-soluble form of bilirubin that has been processed by the liver.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Indirect bilirubin (also known as unconjugated bilirubin) is a fat-soluble waste product generated during the normal breakdown of red blood cells, specifically from the heme component of hemoglobin.
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Bilirubin is a yellowish pigment that is produced when red blood cells break down in the body.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Bilirubin-to-Albumin Ratio (B/A Ratio) integrates bilirubin production and albumin-bound clearance.
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The De Ritis ratio compares two key liver enzymes: AST (aspartate aminotransferase) and ALT (alanine aminotransferase).
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Ferritin is a blood protein that contains iron¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Ferritin-to-Albumin Ratio (FAR) integrates inflammation (ferritin) and nutritional status (albumin).
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: ferritin, albumin.
γ-Glutamyl Transferase (GGT) is an enzyme primarily found in the liver, with elevated levels indicating potential liver dysfunction, oxidative stress, or cardiovascular risk¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The GGT-to-HDL Cholesterol Ratio (GGT/HDL-C) reflects oxidative stress versus lipid vascular protection.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Globulin is a type of protein that is made by the liver and the immune system.
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The Indirect-to-Direct Bilirubin Ratio (I/D Ratio) reflects bilirubin metabolism, conjugation, and clearance.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: indirect bilirubin, direct bilirubin.
Macrocytosis refers to the presence of enlarged red blood cells (RBCs) - cells that have a higher-than-normal volume, typically defined as a mean corpuscular volume (MCV) greater than 100 fL.
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Microcytosis refers to the presence of small red blood cells (RBCs), typically defined by a low mean cell volume (MCV) - usually less than 80 fL.
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Total Protein measures the total amount of two classes of proteins found in the plasma: albumin and globulin.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Urine appearance describes the visual clarity of urine and reflects the presence or absence of suspended particles such as cells, bacteria, proteins, crystals, or mucus.
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Bacteria in urine sediment is measured by automated urinalysis, counting the number of bacteria per high power field.
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Bacteria in urine sediment is checked by examining a urine sample under a microscope.
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Urine bilirubin measures the presence of bilirubin, a yellow pigment produced from the breakdown of red blood cells, in the urine.
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Urine bilirubin measures the presence of bilirubin, a yellow pigment produced from the breakdown of red blood cells, in the urine.
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Calcium is one of the most important and common minerals in your body.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Urine character describes the visual clarity of urine and reflects the presence or absence of suspended particles such as cells, bacteria, proteins, crystals, or mucus.
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Chloride is a type of electrolyte that carries an electric charge and helps control the amount of fluids and the balance of acids and bases (pH balance) in your body¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Urine color is an indirect visual indicator of kidney function, fluid balance, and systemic metabolism.
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Urine color is an indirect visual indicator of kidney function, fluid balance, and systemic metabolism.
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Corrected calcium is a calculated value that adjusts your measured total serum calcium based on your albumin level.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: total calcium, albumin.
Creatinine is a waste product that comes from the normal wear and tear on muscles of the body³.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The CRP-to-Albumin Ratio (CAR) integrates inflammation (CRP) with nutritional/hepatic reserve (albumin).
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Urine crystals are solid formations that can appear in urine sediment when certain dissolved substances precipitate out of solution.
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Cystatin C is a small protein made by nearly all cells in the body and released into the bloodstream at a constant rate.
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Method Cystatin C: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis. Method eGFR: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Asymmetric dimethylarginine (ADMA) is a small molecule that comes from the normal breakdown of proteins in the body.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Symmetric dimethylarginine (SDMA) is a small molecule that comes from the natural breakdown of proteins in the body.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Epithelial casts are cylindrical structures found in urine sediment that contain renal tubular epithelial cells trapped within a protein matrix.
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Epithelial cells in urine sediment are counted by automated urinalysis.
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Renal epithelial cells are specialized cells that line the kidney tubules.
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Squamous epithelial cells are flat cells that line the outer portion of the urinary tract and surrounding skin.
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Fatty casts are cylindrical structures found in urine sediment that contain lipid droplets or fat-laden cells within a protein matrix.
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Estimated glomerular filtration rate (eGFR) is a calculation that reflects how well the kidneys are functioning by estimating the volume of blood they filter each minute, adjusted to a standard body surface area (mL/min/1.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Estimated glomerular filtration rate (eGFR) is a calculation that reflects how well the kidneys are functioning by estimating the volume of blood they filter each minute, adjusted to a standard body surface area (mL/min/1.
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Globulin is a type of protein that is made by the liver and the immune system.
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Urine glucose measures the presence of glucose, the body's primary fuel derived from dietary carbohydrates, in the urine.
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Urine glucose measures the presence of glucose, the body's primary fuel derived from dietary carbohydrates, in the urine.
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Granular casts are cylindrical structures found in urine sediment that contain granular material from degenerating cells or aggregated proteins.
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Urine occult blood measures the presence of red blood cells or hemoglobin in the urine that may be invisible to the naked eye.
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Urine occult blood measures the presence of red blood cells or hemoglobin in the urine that may be invisible to the naked eye.
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Hyaline casts are cylindrical protein structures formed in the kidney tubules and detected in urine by automated urinalysis.
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Urine ketone confirmation (Acetest) is a follow-up test that confirms the presence of ketone bodies using a different analytical method than the initial dipstick screening.
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Urine ketones measure the presence of ketone bodies, which are byproducts of fat metabolism produced when the body uses fat instead of glucose as its primary energy source.
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Urine ketones measure the presence of ketone bodies, which are byproducts of fat metabolism produced when the body uses fat instead of glucose as its primary energy source.
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Urine leukocyte esterase measures the presence of esterase, an enzyme released by activated white blood cells (neutrophils) in the urinary tract.
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Urine leukocyte esterase measures the presence of esterase, an enzyme released by activated white blood cells (leukocytes) involved in immune defense.
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Urine nitrite measures the presence of nitrites formed when certain bacteria convert naturally occurring urinary nitrates into nitrites.
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Urine nitrite measures the presence of nitrites formed when certain bacteria convert naturally occurring urinary nitrates into nitrites.
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Represents kidney, bladder, and reproductive system health.
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Urine pH measures the acidity or alkalinity of urine and reflects the body's regulation of acid-base balance through the kidneys.
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Urine pH measures the acidity or alkalinity of urine and reflects the body's regulation of acid-base balance through the kidneys.
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Potassium is a mineral and an electrolyte that is critical for many body functions, including nerve signals, muscle contractions, heart rhythms, blood pressure, fluid balance, and pH balance¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Total Protein measures the total amount of two classes of proteins found in the plasma: albumin and globulin.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Urine protein measures the presence of protein in the urine and reflects the integrity of the kidney's filtration barrier.
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Urine protein measures the presence of protein in the urine and reflects the integrity of the kidney's filtration barrier.
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Urinary red blood cells (RBCs) measure the presence of intact red blood cells detected by automated urinalysis.
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Red blood cell (RBC) casts are cylindrical structures found in urine sediment that contain intact red blood cells trapped within a protein matrix.
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Urinary red blood cells (RBCs) measure the presence of intact red blood cells detected by urine microscopy.
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Urine reducing substances (Clinitest) measures the presence of reducing sugars and other reducing compounds in urine using a chemical reaction method.
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Sodium is a mineral and an electrolyte that is essential for many body functions, including nerve signals, muscle contractions, fluid balance, blood pressure, and pH balance¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Urine specific gravity measures the concentration of dissolved particles in urine relative to pure water and reflects the kidneys' ability to regulate fluid balance by concentrating or diluting urine.
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Urine specific gravity measures the concentration of dissolved particles in urine relative to pure water and reflects the kidneys' ability to regulate fluid balance by concentrating or diluting urine.
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Spermatozoa in urine are detected by automated urinalysis and indicate the presence of sperm cells in the urine sample.
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Trichomonas detection in urine identifies the presence of Trichomonas vaginalis, a parasitic protozoan that causes trichomoniasis, a common sexually transmitted infection.
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Uric acid is a waste product that is formed when the body breaks down purines, which are chemicals found in some foods and drinks, such as red meat, organ meats, seafood, beer and fructose-sweetened beverages³.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
BUN/Creatinine ratio is a calculation that compares the levels of blood urea nitrogen (BUN) and creatinine in your blood.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
BUN stands for blood urea nitrogen, which is a waste product that is produced when your body breaks down the protein in the foods you eat.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Urea-to-Creatinine Ratio (UCR) provides insight into renal stress, hydration, protein metabolism, and pre-renal vs.
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The Uric Acid-to-HDL Cholesterol Ratio (UHR) integrates oxidative/inflammatory load (uric acid) with HDL’s vascular protection.
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Urine urobilinogen measures the concentration of urobilinogen, a byproduct of bilirubin metabolism produced by intestinal bacteria.
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Waxy casts are cylindrical structures found in urine sediment with a smooth, waxy appearance.
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Urine white blood cells (WBCs) measure the presence of immune cells in the urine and indicate inflammatory activity within the urinary tract.
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White blood cell (WBC) casts are cylindrical structures found in urine sediment that contain white blood cells trapped within a protein matrix.
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Urine white blood cells (WBCs) measure the presence of immune cells in the urine and indicate inflammatory activity within the urinary tract.
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Yeast cells in urine are detected by automated urinalysis and indicate the presence of fungal organisms, most commonly Candida species.
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High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.
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The CRP-to-Albumin Ratio (CAR) integrates inflammation (CRP) with nutritional/hepatic reserve (albumin).
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Erythrocyte sedimentation rate (ESR), or sedimentation rate measures how quickly erythrocytes (red blood cells) settle at the bottom of a test tube over a period of one hour.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Ferritin/CRP ratio compares two important biomarkers: ferritin, which stores and reflects iron levels, and C-reactive protein (CRP), a sensitive marker of inflammation.
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Ferritin is a blood protein that contains iron¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Ferritin-to-Albumin Ratio (FAR) integrates inflammation (ferritin) and nutritional status (albumin).
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: ferritin, albumin.
The Lymphocyte-to-Monocyte Ratio (LMR) reflects the balance between adaptive immune function (lymphocytes) and innate immune activation (monocytes).
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: lymphocytes, monocytes.
The Monocyte-to-HDL Ratio (MHR) reflects the balance between inflammation and cardiovascular protection.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: monocytes, HDL-C.
The Monocyte-to-Lymphocyte Ratio (MLR) captures the balance between innate inflammatory processes (monocytes) and adaptive immune response (lymphocytes).
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: monocytes, lymphocytes.
The Neutrophil-to-HDL Cholesterol Ratio (NHR) integrates innate immune activation (neutrophils) with HDL-C’s protective effects.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, HDL-C.
The Neutrophil-to-(Lymphocyte × Platelet) Ratio (NLPR) combines neutrophils, lymphocytes, and platelets to reflect inflammatory burden, adaptive immunity, and repair capacity.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, lymphocytes, platelets.
The Neutrophil-to-Lymphocyte Ratio (NLR) reflects balance between innate and adaptive immunity.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, lymphocytes.
Reflects how well your lungs and oxygen systems are functioning.
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The Platelet-to-Lymphocyte Ratio (PLR) reflects thrombo-inflammatory burden and immune balance by combining platelet activity with adaptive immune status.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: platelets, lymphocytes.
The Platelet-to-WBC Ratio (PWR) compares platelet counts with total white blood cell counts.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: platelets, WBC.
Rheumatoid factor (RF) is an autoantibody - an antibody directed against the body’s own tissues rather than foreign invaders.
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The Systemic Immune-Inflammation Index (SII) integrates platelets, neutrophils, and lymphocytes.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: CBC differentials.
The Systemic Inflammation Response Index (SIRI) = (neutrophils × monocytes) / lymphocytes, integrating innate inflammatory activity with adaptive immune regulation.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, monocytes, lymphocytes.
WBCs are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders³.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Alternaria alternata IgE measures your immune system's specific allergic antibody response to spores produced by Alternaria alternata, one of the most common outdoor molds worldwide.
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Aspergillus fumigatus IgE measures your immune system's specific allergic antibody response to spores produced by Aspergillus fumigatus, a common environmental mold found in soil, decaying organic matter, compost, and indoor environments with moisture problems.
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Dermatophagoides farinae IgE measures your immune system's specific allergic antibody response to proteins produced by the American house dust mite.
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Bands (or band neutrophils) are immature white blood cells that develop into fully functional neutrophils - key players in the body’s innate immune system, which serves as the first line of defense against infection.
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Basophils are a type of white blood cell that the bone marrow makes.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Basophils are a type of white blood cell that are part of the immune system.
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Bermuda grass IgE measures your immune system's specific allergic antibody response to proteins found in Bermuda grass pollen.
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Absolute Blast Count measures the actual number of blast cells - very immature blood cells circulating in the bloodstream.
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Burr cells, also known as echinocytes (or “hedgehog cells”), are red blood cells with a spiky or serrated outer surface, giving them a thorny appearance that contrasts with the smooth, disc-shaped profile of healthy red blood cells.
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Cat dander IgE measures your immune system's specific allergic antibody response to proteins produced by cats — primarily Fel d 1, which is found in cat skin flakes (dander), saliva, and urine.
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Cockroach IgE measures your immune system's specific allergic antibody response to proteins found in cockroach saliva, droppings, shed body parts, and decomposing remains.
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Rough pigweed IgE measures your immune system's specific allergic antibody response to proteins found in rough pigweed pollen.
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Common ragweed IgE measures your immune system's specific allergic antibody response to proteins found in short ragweed pollen.
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High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.
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Cyclic Citrullinated Peptide (CCP) antibodies are autoantibodies that target proteins in the body that have undergone a process called citrullination.
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Cyclic Citrullinated Peptide (CCP) antibodies are autoantibodies that target proteins in the body that have undergone a process called citrullination.
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Double-stranded DNA (dsDNA) antibodies are autoantibodies that target the body’s own genetic material - specifically, the double-helix structure of DNA inside the cell nucleus.
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Dog dander IgE measures your immune system's specific allergic antibody response to proteins produced by dogs — primarily Can f 1, found in dog dander, saliva, and urine.
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Eosinophils are a type of white blood cell that are part of the immune system².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Eosinophils are a type of white blood cell and a component of the immune system, playing a crucial role in the body's defense against parasitic infections, allergens, and in mediating allergic reactions.
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Erythrocyte sedimentation rate (ESR), or sedimentation rate measures how quickly erythrocytes (red blood cells) settle at the bottom of a test tube over a period of one hour.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Dermatophagoides pteronyssinus IgE measures your immune system's specific allergic antibody response to proteins produced by the European house dust mite.
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Ferritin is a blood protein that contains iron¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Immunoglobulin A (IgA) is one of the body’s main types of antibodies and plays a central role in the immune defenses that protect the body’s mucosal surfaces — the thin, moist linings of the gut, airways, mouth, and eyes.
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Immunoglobulin G (IgG) is the most abundant antibody in the bloodstream and tissues, accounting for roughly 75% of all circulating immunoglobulins.
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Other, Lineage Uncertain refers to cells found in the blood that cannot be confidently classified into a specific blood cell family - such as white blood cells (immune cells), red blood cells, or platelets.
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Immature granulocytes are white blood cells that have not fully developed before being released from the bone marrow into the blood¹.
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Immature granulocytes (IGs) are early-stage white blood cells that play a crucial role in the body's immune response, particularly during infection or inflammation.
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Sycamore IgE measures your immune system's specific allergic antibody response to proteins found in sycamore tree pollen.
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Lymphocytes are a type of white blood cell that are part of the immune system.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Lymphocytes are a type of white blood cell that are integral to the immune system.
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Lymphocytes are a type of white blood cell that are integral to the immune system.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Megakaryocytes are large, specialized cells found in the bone marrow that are responsible for producing platelets - the tiny cell fragments that help your blood clot and stop bleeding.
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Metamyelocytes are immature white blood cells that are part of your body's early immune defense system.
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Metamyelocytes are immature granulocytes normally absent in healthy peripheral blood.
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Monocytes are a type of white blood cell that are produced in the bone marrow and then enter the bloodstream⁴.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Monocytes are a type of white blood cell that are part of the immune system.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Mononuclear cells are a group of white blood cells characterized by having a single, round nucleus.
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Mountain cedar IgE measures your immune system's specific allergic antibody response to proteins found in mountain cedar pollen.
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Mugwort IgE measures your immune system's specific allergic antibody response to proteins found in mugwort pollen.
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Myelocytes are immature white blood cells in the granulocyte lineage — a group of immune cells that includes neutrophils, eosinophils, and basophils, all of which help defend the body against infection and inflammation.
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Neutrophils are a type of white blood cell and the most abundant type of granulocytes in the bloodstream, playing a crucial role in the body's first line of defense against infection.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Neutrophils are a type of white blood cell and the most abundant type of granulocytes in the bloodstream, playing a crucial role in the body's first line of defense against infection.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Antinuclear Antibody (ANA) screen is a broad test that looks for antibodies directed against the nucleus of your own cells.
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The Antinuclear Antibody (ANA) screen is a broad test that looks for antibodies directed against the nucleus of your own cells.
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NRBC (Nucleated Red Blood Cells) are immature red blood cells that still contain a nucleus.
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Represents the strength and regulation of your immune system.
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Penicillium notatum IgE measures your immune system's specific allergic antibody response to spores and proteins produced by Penicillium notatum (now known as Penicillium chrysogenum), a common indoor and outdoor mold.
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Mean Platelet Volume (MPV) measures the average size of your platelets - the small cell fragments in your blood that help with clotting, wound repair, and inflammation control.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Mean Platelet Volume (MPV) measures the average size of your platelets - the small cell fragments in your blood that help with clotting, wound repair, and inflammation control.
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Platelets are tiny components of your blood that help with clotting.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Prolymphocytes are immature lymphocytes which are developing cells on their way to becoming fully functional B-cells or T-cells, which are central to your body’s adaptive immune system.
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Promyelocytes are immature white blood cells that belong to the granulocyte lineage - the family of immune cells that includes neutrophils, eosinophils, and basophils.
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Rheumatoid factor (RF) is an autoantibody - an antibody directed against the body’s own tissues rather than foreign invaders.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Birch IgE measures your immune system's specific allergic antibody response to proteins found in birch tree pollen.
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Sjogren’s Antibody (SS-A, also called Ro) is an autoantibody that targets proteins bound to RNA inside the nucleus and cytoplasm.
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Anti-SSA 60 (Ro60) is one of the two main subtypes of SS-A antibodies (the other being SSA 52).
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Sjogren’s Antibody (SS-B, also called La) is an autoantibody that targets the La protein, a nuclear protein involved in stabilizing RNA molecules and assisting with their proper processing.
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Smith (Sm) antibodies are autoantibodies - antibodies that mistakenly target the body’s own cells rather than external threats like bacteria or viruses.
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Timothy grass IgE measures your immune system's specific allergic antibody response to proteins found in Timothy grass pollen.
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RNP antibodies are autoantibodies directed against ribonucleoproteins, molecules made of RNA and proteins that are essential for normal cell function.
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Atypical lymphocytes - also called reactive lymphocytes - are white blood cells that appear larger and more irregular than typical lymphocytes when viewed under a microscope.
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WBCs are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders³.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
White ash IgE measures your immune system's specific allergic antibody response to proteins found in white ash tree pollen.
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Elm IgE measures your immune system's specific allergic antibody response to proteins found in elm tree pollen.
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White mulberry IgE measures your immune system's specific allergic antibody response to proteins found in white mulberry tree pollen.
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Oak IgE measures your immune system's specific allergic antibody response to proteins found in oak tree pollen.
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Apolipoprotein B (ApoB) is a protein that has many functions in the body, such as transporting lipids (fats), regulating cholesterol metabolism, maintaining blood vessel integrity, and modulating immune responses¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Atherogenic Coefficient (AC) is a simple ratio that shows how much of your total cholesterol is made up of potentially harmful types - specifically, all cholesterol except HDL, the “good” cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Total-C, HDL-C.
The Atherogenic Index of Plasma (AIP) is calculated as the logarithm of the ratio between triglycerides and HDL cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: TG, HDL-C.
The Castelli Risk Index I (CRI-I) is a cardiovascular risk marker calculated by dividing total cholesterol by HDL cholesterol.
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The Castelli Risk Index II (CRI-II) is a lipid ratio calculated by dividing LDL cholesterol (“bad” cholesterol) by HDL cholesterol (“good” cholesterol).
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HDL cholesterol is a type of cholesterol that is carried by high-density lipoproteins (HDL) in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL cholesterol is a type of cholesterol that is carried by low-density lipoproteins (LDL) in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The LDL/HDL ratio shows the balance between 'bad' LDL cholesterol and 'good' HDL cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
LDL size refers to the average diameter of low-density lipoprotein (LDL) particles circulating in the bloodstream.
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VLDL cholesterol stands for very-low-density lipoprotein cholesterol.
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Total cholesterol is a measure of the total amount of cholesterol in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Non-HDL cholesterol is a stronger predictor of cardiovascular risk than LDL alone, especially in contexts with elevated triglycerides.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Total Cholesterol/HDL ratio measures the balance between all cholesterol in the blood and the 'good' HDL cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Total carbon dioxide (CO2) is a measure of the amount of carbon dioxide in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.
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The CRP-to-Albumin Ratio (CAR) integrates inflammation (CRP) with nutritional/hepatic reserve (albumin).
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Cystatin C is a small protein made by nearly all cells in the body and released into the bloodstream at a constant rate.
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Method Cystatin C: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis. Method eGFR: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Asymmetric dimethylarginine (ADMA) is a small molecule that comes from the normal breakdown of proteins in the body.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Symmetric dimethylarginine (SDMA) is a small molecule that comes from the natural breakdown of proteins in the body.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
The GGT-to-HDL Cholesterol Ratio (GGT/HDL-C) reflects oxidative stress versus lipid vascular protection.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis.
Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The LDL Cholesterol-to-Apolipoprotein B Ratio (LDL-C/ApoB) reflects cholesterol content per LDL particle and indicates LDL particle size/density.
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Oxidized LDL (oxLDL) measures the amount of low-density lipoprotein cholesterol that has undergone oxidative modification.
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The LDL / Total Cholesterol ratio is a simple calculation that expresses the proportion of total cholesterol that is made up of low-density lipoproteins (LDL), commonly referred to as “bad cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: LCL-C, Total Cholesterol.
Lipoprotein (a) or Lp(a) is a macromolecular complex composed of one molecule of Low-Density Lipoprotein (LDL) containing apolipoprotein B100 and one molecule of apolipoprotein(a)¹.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
LDL-P refers to the total number of low-density lipoprotein (LDL) particles circulating in the blood, measured in nanomoles per liter (nmol/L).
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HDL Size is the average diameter of high-density lipoprotein (HDL) particles in your blood, typically measured in nanometers (nm) using nuclear magnetic resonance (NMR) spectroscopy.
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HDL-P (Total) refers to the total number of high-density lipoprotein (HDL) particles in the blood.
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Large HDL-P is the concentration of large, buoyant high-density lipoprotein (HDL) particles in your blood, measured in nanomoles per liter (nmol/L) using nuclear magnetic resonance (NMR) spectroscopy.
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LDL size refers to the average diameter of low-density lipoprotein (LDL) particles circulating in the bloodstream.
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LDL-P refers to the total number of low-density lipoprotein (LDL) particles circulating in the blood, measured in nanomoles per liter (nmol/L).
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Small LDL-P refers to the concentration of small, dense low-density lipoprotein particles in the bloodstream, measured in nanomoles per liter (nmol/L) using advanced nuclear magnetic resonance (NMR) spectroscopy.
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VLDL Size is the average diameter of very-low-density lipoprotein (VLDL) particles in your bloodstream, typically measured in nanometers (nm) using nuclear magnetic resonance (NMR) spectroscopy.
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Large VLDL-P measures the concentration of the largest, triglyceride-rich very-low-density lipoprotein (VLDL) particles in circulation.
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The Monocyte-to-HDL Ratio (MHR) reflects the balance between inflammation and cardiovascular protection.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: monocytes, HDL-C.
The Neutrophil-to-HDL Cholesterol Ratio (NHR) integrates innate immune activation (neutrophils) with HDL-C’s protective effects.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: neutrophils, HDL-C.
The Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB) reflects cholesterol content per atherogenic particle across LDL, VLDL, IDL, and Lp(a).
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Non-HDL-C, ApoB.
The Non-HDL / Total Cholesterol ratio measures the proportion of your total cholesterol that is carried by potentially harmful lipoproteins - all cholesterol excluding HDL, which is considered “good cholesterol.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: Non-HDL-C, Total-C.
Assesses the health of your heart, blood vessels, and circulation.
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The Triglyceride / HDL Cholesterol ratio is a powerful marker of insulin resistance, metabolic syndrome, and cardiovascular risk.
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Triglycerides are a type of fat, or lipid, found in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB) estimates the triglyceride load per atherogenic particle.
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The TyG Index is a metabolic risk marker calculated using fasting triglycerides and fasting glucose.
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Uric acid is a waste product that is formed when the body breaks down purines, which are chemicals found in some foods and drinks, such as red meat, organ meats, seafood, beer and fructose-sweetened beverages³.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Globulin is a type of protein that is made by the liver and the immune system.
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Method: Derived from FDA-cleared laboratory results. This ratio/index is not an FDA-cleared test. It aids clinician-directed risk assessment and monitoring and is not a stand-alone diagnosis. Inputs: albumin, globulin.
Albumin is a protein made by the liver that has many functions in the body, such as maintaining fluid balance, transporting substances including hormones and vitamins, regulating blood pressure, preventing blood clotting, and providing nutrition¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
The Bilirubin-to-Albumin Ratio (B/A Ratio) integrates bilirubin production and albumin-bound clearance.
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Globulin is a type of protein that is made by the liver and the immune system.
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Captures the health of your digestive and liver systems.
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Total Protein measures the total amount of two classes of proteins found in the plasma: albumin and globulin.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Tissue Transglutaminase Antibody, IgA (tTG-IgA), is an autoantibody produced when the immune system reacts abnormally to gluten - a protein found in wheat, barley, and rye.
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Tissue Transglutaminase Antibody, IgA (tTG-IgA), is an autoantibody produced when the immune system reacts abnormally to gluten - a protein found in wheat, barley, and rye.
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Aspartate aminotransferase (AST) is an enzyme that helps break down amino acids and is found in various tissues, such as the liver, heart, muscles, kidneys, and brain.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Creatine Phosphokinase (CK), also known as Creatine Kinase, is an enzyme found primarily in the heart, brain, and skeletal muscle tissues¹.
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Total carbon dioxide (CO2) is a measure of the amount of carbon dioxide in your blood.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Adrenocorticotropic hormone (ACTH) is a hormone made by the pituitary gland that signals the adrenal glands to produce cortisol.
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Cortisol is a hormone made by the adrenal glands that helps you respond to stress and regulate various bodily functions.
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Cortisol is a hormone made by the adrenal glands that helps you respond to stress and regulate various bodily functions.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
DHEA-Sulfate (DHEA-S) is a steroid hormone that is made by the adrenal glands and converted into sex hormones such as estrogen and testosterone.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Insulin-like Growth Factor-1 (IGF-1) is a hormone similar in molecular structure to insulin¹.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
The IGF-1 Z Score is the number of standard deviations an IGF-1 result is above or below the age- and sex-matched population mean (SD units).
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Measures bone, muscle, and connective tissue integrity.
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Systemic Organ Age reflects how your entire body’s internal regulatory networks—metabolic, inflammatory, hormonal—are functioning relative to your chronological age.
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The Testosterone-to-Estradiol Ratio (T/E₂) reflects androgen–estrogen balance.
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Vitamin B12 (cobalamin) is a water-soluble vitamin that plays a central role in energy production, DNA synthesis, red blood cell formation, and nervous system health.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Ferritin is a blood protein that contains iron¹².
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Folate is a type of vitamin B that is essential for the production and maintenance of new cells, especially during periods of rapid growth, such as pregnancy, infancy, and adolescence.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Red blood cell folate measures the concentration of folate stored inside red blood cells.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Iron is a mineral that is essential for many biological processes in the body, such as oxygen transport, muscle activity, mitochondrial function, DNA synthesis, and sensing of hypoxia⁵.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Methylmalonic acid (MMA) is a small organic acid that builds up when the body cannot properly use vitamin B12 (cobalamin).
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Vitamin B6 (pyridoxine) is one of the essential B-vitamins, and it works in its active form called pyridoxal-5’-phosphate (PLP).
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Vitamin B6 (pyridoxine) is one of the essential B-vitamins, and it works in its active form called pyridoxal-5’-phosphate (PLP).
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Vitamin B2 (riboflavin) is a water-soluble vitamin that serves as the building block for two key coenzymes: flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
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Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time. Derived from laboratory results. This score or index is not an FDA-cleared test. It aids clinician-directed assessment and is not a stand-alone diagnosis.
Vitamin B2 (riboflavin) is a water-soluble vitamin that serves as the building block for two key coenzymes: flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
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Vitamin D is an essential and multifunctional micronutrient.
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Method: Usually performed by FDA-cleared immunoassay in CLIA-certified, CAP-accredited laboratories. If an LC/MS method is used at the performing site, the assay is a laboratory-developed test (LDT) validated under CLIA and not cleared or approved by the FDA. Results support clinician interpretation and are not a stand-alone diagnosis.
The AB42/40 ratio is a calculated value derived from your plasma amyloid beta 42 and amyloid beta 40 levels.
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Amyloid beta 40 (AB40) is a small protein fragment produced when the brain processes amyloid precursor protein (APP).
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Amyloid beta 42 (AB42) is a 42-amino acid protein fragment produced when the brain processes amyloid precursor protein (APP).
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Vitamin B12 (cobalamin) is a water-soluble vitamin that plays a central role in energy production, DNA synthesis, red blood cell formation, and nervous system health.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Adrenocorticotropic hormone (ACTH) is a hormone made by the pituitary gland that signals the adrenal glands to produce cortisol.
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Cortisol is a hormone made by the adrenal glands that helps you respond to stress and regulate various bodily functions.
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Cortisol is a hormone made by the adrenal glands that helps you respond to stress and regulate various bodily functions.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
High-sensitivity CRP is a blood test that measures very subtle levels of inflammation in the body.
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Estradiol is the most potent form of estrogen, a hormone produced by both males and females, albeit in different amounts.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Folate is a type of vitamin B that is essential for the production and maintenance of new cells, especially during periods of rapid growth, such as pregnancy, infancy, and adolescence.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
T4 and T3 are thyroid hormones that regulate the metabolism of the body.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Homocysteine is an amino acid, which is a molecule that your body uses to make proteins.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Insulin-like Growth Factor-1 (IGF-1) is a hormone similar in molecular structure to insulin¹.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Fasting insulin reflects how much insulin the pancreas produces after an overnight fast.
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Insulin is a hormone that is produced by the pancreas and regulates the metabolism of glucose, fat and protein.
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Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.
Linoleic acid is a polyunsaturated omega-6 fatty acid that's essential for human health.
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Reflects the biological aging of the brain and cognitive system.
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Tracks the resilience of your nervous system - the communication network between brain and body.
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Phosphorylated tau 217 (pTau-217) is a modified form of tau — a structural protein that normally stabilizes the internal scaffolding of brain cells.
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Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Bioavailable testosterone represents the fraction of testosterone in the blood that is readily available to tissues.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Testosterone is a hormone that is mainly produced by the testicles in males and the ovaries in females, but also by the adrenal glands in both sexes.
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Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.
Like all comprehensive health platforms, Superpower provides derived biomarkers. Derived biomarkers are standard clinical tools used by healthcare providers worldwide.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
The following biomarkers Progesterone, Vitamin K, ADMA/SDMA, IGF-1, Thyroid Peroxidase, Lipoprotein Fractionation, NMR and Thyroglobulin Antibody are not currently offered for Superpower members residing in New York/New Jersey. Some methods are laboratory-developed tests (LDTs) validated under CLIA but not cleared or approved by the U.S. FDA. Public claims mirror the performing laboratory’s intended-use language. Clinicians interpret results in context and may order confirmatory testing where appropriate.