L-Glutamine

Support your gut health and muscle recovery with L-Glutamine as part of your daily wellness routine.

December 5, 2025
Author
Superpower Science Team
Reviewed by
Julija Rabcuka
PhD Candidate at Oxford University
Creative
Jarvis Wang

Key Facts

  • L-glutamine is a conditionally essential amino acid that becomes critical during physical stress, illness, or intense training
  • Supports muscle repair, gut barrier integrity, and immune cell function
  • Particularly relevant for athletes and anyone experiencing high metabolic demand

Ingredients

L-glutamine, hypromellose capsule, silicon dioxide.

Why We Chose This

Your gut lining and immune cells are voracious glutamine consumers, especially when you're training hard or under stress. During these periods, your body's demand for this amino acid outpaces what you can synthesize on your own. Thorne's L-glutamine formulation delivers 500 mg per capsule in a clean, straightforward dose. The research supporting glutamine for muscle recovery and intestinal barrier function is solid, making this a practical choice for anyone looking to support both athletic performance and digestive resilience without unnecessary additives.

Frequently Asked Questions About L-Glutamine

What is the supporting research for the benefits of L-glutamine?
  • Oral glutamine is associated with reduced IBS symptom severity in trials. (IBS-D RCT)
  • Glutamine supplementation is associated with reduced intestinal permeability markers. (systematic review)
How do I take L-glutamine?

Take 1-2 capsules daily with food, ideally splitting doses throughout the day to support muscle repair and gut health.

Most people start with 5-10 grams per day, though your healthcare provider can help determine what works best for your needs.

Can I take L-glutamine with other supplements or medications?

L-glutamine has minimal documented interactions with most supplements and medications, though it may affect anticonvulsant drugs. Always discuss your current regimen with your healthcare provider before starting.

Who might benefit from taking L-glutamine?

Athletes and those under physical stress benefit from L-glutamine supplementation to support muscle repair and immune function. People recovering from injury, surgery, or illness may also find it helpful for maintaining gut health and reducing infection risk.

How long does it typically take to notice effects of L-glutamine?

You may start noticing benefits in as little as a few weeks, though full gut healing is a longer process. L-glutamine isn't a stimulant you'll "feel" kick in — instead, you'll observe improvements in digestion, energy, and recovery over time.