L-Glutamine

Amino Acids

L-Glutamine

L‑Glutamine is a conditionally essential amino acid that fuels muscle recovery, supports immune function, and helps repair the intestinal lining. It may reduce post‑workout soreness, speed recovery after intense training, and support digestive health issues like gut permeability and IBS symptoms.

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Key Facts

L-glutamine is a conditionally essential amino acid that becomes critical during physical stress, illness, or intense training
Supports muscle repair, gut barrier integrity, and immune cell function
Particularly relevant for athletes and anyone experiencing high metabolic demand

Ingredients

L-glutamine, hypromellose capsule, silicon dioxide.

Why We Chose This

Your gut lining and immune cells are voracious glutamine consumers, especially when you're training hard or under stress. During these periods, your body's demand for this amino acid outpaces what you can synthesize on your own. Thorne's L-glutamine formulation delivers 500 mg per capsule in a clean, straightforward dose. The research supporting glutamine for muscle recovery and intestinal barrier function is solid, making this a practical choice for anyone looking to support both athletic performance and digestive resilience without unnecessary additives.

Other Amino Acids

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Glycine

Glycine is a simple, naturally occurring amino acid that supports restful sleep, a calm nervous system, and healthy collagen production. It may help with sleep disturbances, stress-related tension, muscle and joint recovery, and signs of skin aging.

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L-Glutamine Powder

L-Glutamine Powder is a pure amino acid supplement that helps replenish glutamine used during intense exercise to support faster muscle recovery and reduce post-workout soreness. It may also support immune function and gut health by helping maintain intestinal barrier integrity and aiding recovery from digestive stress.

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PharmaGABA-250

PharmaGABA-250 delivers 250 mg of naturally fermented GABA to support relaxation and a calm mood, helping promote restful sleep. It may help with everyday stress, occasional sleeplessness, and mild nervous tension.

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PharmaGABA-100

PharmaGABA-100 is a fermented, bioavailable form of the neurotransmitter GABA designed to promote relaxation and calm. It may help reduce stress and anxiety, support restful sleep, and promote a balanced mood to help you unwind and recover.

Learn more

Theanine

L‑theanine is a calming amino acid (found in tea) that promotes relaxed alertness—reducing stress and anxiety and improving focus without drowsiness. It may also help improve sleep quality, blunt stress‑related blood pressure spikes, and enhance cognitive performance when combined with caffeine.

Learn more

Frequently Asked Questions About L-Glutamine

What is the supporting research for the benefits of L-glutamine?

Oral glutamine is associated with reduced IBS symptom severity in trials. (IBS-D RCT)
Glutamine supplementation is associated with reduced intestinal permeability markers. (systematic review)

How do I take L-glutamine?

Take 1-2 capsules daily with food, ideally splitting doses throughout the day to support muscle repair and gut health.

Most people start with 5-10 grams per day, though your healthcare provider can help determine what works best for your needs.

Can I take L-glutamine with other supplements or medications?

L-glutamine has minimal documented interactions with most supplements and medications, though it may affect anticonvulsant drugs. Always discuss your current regimen with your healthcare provider before starting.

Who might benefit from taking L-glutamine?

Athletes and those under physical stress benefit from L-glutamine supplementation to support muscle repair and immune function. People recovering from injury, surgery, or illness may also find it helpful for maintaining gut health and reducing infection risk.

How long does it typically take to notice effects of L-glutamine?

You may start noticing benefits in as little as a few weeks, though full gut healing is a longer process. L-glutamine isn't a stimulant you'll "feel" kick in — instead, you'll observe improvements in digestion, energy, and recovery over time.

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