Glycine

Amino Acids

Glycine

Glycine is a simple, naturally occurring amino acid that supports restful sleep, a calm nervous system, and healthy collagen production. It may help with sleep disturbances, stress-related tension, muscle and joint recovery, and signs of skin aging.

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Key Facts

Glycine is a simple amino acid that acts as an inhibitory neurotransmitter, helping calm your nervous system
Supports relaxation, stress management, and sleep quality by elevating serotonin levels
Enhances liver detoxification through glutathione production and serves as a building block for collagen
Thorne's formulation meets rigorous quality standards for consistent potency

Ingredients

Glycine, hypromellose capsule, silicon dioxide.

Why We Chose This

Glycine addresses a common gap: many people struggle with stress and sleep without reaching for pharmaceuticals. This amino acid works by calming your central nervous system—think of it as your brain's natural "off switch." Beyond sleep support, glycine enhances your body's detoxification capacity by boosting glutathione production, your cells' primary antioxidant defense. As a major component of collagen, it also supports muscle and nerve function. We selected Thorne's glycine for its commitment to rigorous quality standards, ensuring you're getting a pure, effective formulation backed by research on longevity and wellness.

Other Amino Acids

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L-Glutamine

L‑Glutamine is a conditionally essential amino acid that fuels muscle recovery, supports immune function, and helps repair the intestinal lining. It may reduce post‑workout soreness, speed recovery after intense training, and support digestive health issues like gut permeability and IBS symptoms.

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L-Glutamine Powder

L-Glutamine Powder is a pure amino acid supplement that helps replenish glutamine used during intense exercise to support faster muscle recovery and reduce post-workout soreness. It may also support immune function and gut health by helping maintain intestinal barrier integrity and aiding recovery from digestive stress.

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PharmaGABA-250

PharmaGABA-250 delivers 250 mg of naturally fermented GABA to support relaxation and a calm mood, helping promote restful sleep. It may help with everyday stress, occasional sleeplessness, and mild nervous tension.

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PharmaGABA-100

PharmaGABA-100 is a fermented, bioavailable form of the neurotransmitter GABA designed to promote relaxation and calm. It may help reduce stress and anxiety, support restful sleep, and promote a balanced mood to help you unwind and recover.

Learn more

Theanine

L‑theanine is a calming amino acid (found in tea) that promotes relaxed alertness—reducing stress and anxiety and improving focus without drowsiness. It may also help improve sleep quality, blunt stress‑related blood pressure spikes, and enhance cognitive performance when combined with caffeine.

Learn more

Frequently Asked Questions About Glycine

What is the supporting research for the benefits of glycine?

Glycine taken before bedtime is associated with improved sleep quality. (sleep performance study)
Glycine appears to lower core body temperature and promote non-REM sleep. (sleep-promoting mechanism study)
Glycine may support muscle preservation and antioxidant defenses. (2024 glycine review)

How do I take glycine?

Take 1-2 capsules daily with water, preferably in the evening to support relaxation and sleep quality.

Most people find 3-5 grams daily effective, though you can adjust based on your individual response and goals.

Can I take glycine with other supplements or medications?

Glycine has minimal interactions with most supplements, though it may enhance effects of antipsychotics, sedatives, and blood pressure medications. Always discuss your full supplement and medication list with your healthcare provider before starting glycine.

Who might benefit from taking glycine?

People struggling with sleep, stress, or cognitive fog benefit from glycine's role as a calming neurotransmitter that supports relaxation and memory. Those focused on muscle recovery, liver health, and longevity also find value in this amino acid's collagen-building and detoxification support.

How long does it typically take to notice effects of glycine?

Glycine reaches your brain within 30–60 minutes, with some noticing sleep benefits within the first few nights. Full effects typically develop over 1–2 weeks of consistent use.

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