

Reading Your Total PSA: A Tissue-Specific Signal From the Prostate
Prostate-specific antigen is a protein enzyme made almost exclusively by the prostate’s glandular cells. It belongs to the kallikrein family of serine proteases (KLK3) and is normally secreted into seminal fluid. Most PSA remains within the ejaculate, but a small fraction passes through the prostate ducts and surrounding tissue into the bloodstream. Available at 2,000+ lab locations and at-home (select states). See FAQs below


Measuring Free PSA: What the Unbound Fraction Adds to a Prostate Reading
Free PSA is the portion of prostate-specific antigen in the bloodstream that is not attached to other proteins. Prostate-specific antigen (PSA) is an enzyme made by prostate gland cells and released mainly into semen; in scientific terms it is a serine protease in the kallikrein family (kallikrein-related peptidase 3, KLK3). Available at 2,000+ lab locations and at-home (select states). See FAQs below






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