Library
/
Sex Hormones
/
Progesterone Test

Progesterone Test

January 21, 2026
Subscribe for updates
By clicking “Subscribe” you agree to our Terms and Privacy Policy.
Your content is on its way!
By clicking “Subscribe” you agree to our TOS and Privacy Policy.
Oops! Something went wrong while submitting the form.

Do I need a Progesterone test?

Struggling with irregular cycles, mood swings, or difficulty sleeping? Could low progesterone be affecting your hormonal balance?

Progesterone plays a key role in regulating your menstrual cycle, supporting pregnancy, and promoting restful sleep. When levels are off, you may experience PMS, anxiety, or disrupted periods.

Testing your progesterone gives you a quick snapshot of your hormonal health, helping you understand whether imbalances are contributing to your symptoms. It's the essential first step to personalizing your treatment plan and reclaiming hormonal balance.

Book your test now
With Superpower, you have access to a comprehensive range of biomarker tests
Book a Progesterone Test Test
Physician reviewed
CLIA-certified labs
HIPAA compliant

Get tested with Superpower

If you’ve been postponing blood testing for years or feel frustrated by doctor appointments and limited lab panels, you are not alone. Standard healthcare is often reactive, focusing on testing only after symptoms appear or leaving patients in the dark.

Superpower flips that approach. We give you full insight into your body with over 100 biomarkers, personalized action plans, long-term tracking, and answers to your questions, so you can stay ahead of any health issues.

With physician-reviewed results, CLIA-certified labs, and the option for at-home blood draws, Superpower is designed for people who want clarity, convenience, and real accountability - all in one place.

Key benefits of Progesterone testing

  • Reveals whether your body is producing enough progesterone to support cycles and pregnancy.
  • Confirms ovulation occurred by detecting the hormone surge after egg release.
  • Explains irregular periods, spotting, or unexplained mood and sleep changes.
  • Guides fertility treatment by showing if progesterone support is needed for conception.
  • Protects early pregnancy by flagging low levels that may increase miscarriage risk.
  • Tracks luteal phase health to identify short cycles that affect fertility.
  • Clarifies perimenopausal symptoms like heavy bleeding or cycle unpredictability.
  • Best interpreted with cycle day, symptoms, and tests like LH or estradiol.

What is Progesterone?

Progesterone is a steroid hormone produced primarily by the ovaries after ovulation, with smaller amounts made by the adrenal glands. In pregnancy, the placenta becomes the major source. It belongs to a family of hormones called progestogens, which play essential roles in reproduction and the menstrual cycle.

The hormone that prepares the body for pregnancy

Progesterone transforms the uterine lining into a nutrient-rich environment ready to support a fertilized egg. It also helps maintain early pregnancy by preventing the uterus from contracting and shedding its lining.

A key player in the menstrual cycle

After ovulation, progesterone levels rise sharply during the second half of the cycle (the luteal phase). If pregnancy doesn't occur, levels drop, triggering menstruation.

Beyond reproduction

Progesterone influences mood, sleep, and bone health. It also counterbalances some effects of estrogen, helping regulate the body's hormonal equilibrium. In men, small amounts support sperm production and nervous system function.

Why is Progesterone important?

Progesterone is a steroid hormone that prepares the body for pregnancy and regulates the menstrual cycle, but it also influences mood, sleep, bone health, and metabolic balance. In women of reproductive age, levels fluctuate dramatically across the cycle - rising after ovulation and falling before menstruation - while remaining consistently low in men and postmenopausal women. Optimal values depend entirely on cycle phase, pregnancy status, and sex.

When progesterone runs low

Insufficient progesterone in the luteal phase can signal poor ovulation or a struggling corpus luteum, leading to irregular periods, difficulty conceiving, or early pregnancy loss. Women may experience heavy bleeding, premenstrual mood swings, anxiety, and sleep disturbances as estrogen goes relatively unopposed. Low levels also reduce the calming effect on the nervous system and may compromise bone density over time.

When progesterone climbs high

Elevated progesterone outside of pregnancy or the luteal phase may point to ovarian cysts, adrenal tumors, or certain cancers. High levels can cause fatigue, bloating, breast tenderness, and sedation. In pregnancy, progesterone naturally soars to sustain the uterine lining, but abnormal spikes warrant investigation.

The bigger hormonal picture

Progesterone works in concert with estrogen, thyroid hormones, and cortisol to shape reproductive health, metabolic function, and emotional resilience. Chronic imbalances increase risks for infertility, osteoporosis, mood disorders, and hormone-sensitive cancers, making progesterone a vital window into endocrine and whole-body wellness.

What do my Progesterone results mean?

Low progesterone values

Low values usually reflect reduced ovarian production after ovulation or absent ovulation altogether. In menstruating women, this often signals anovulatory cycles or a weak luteal phase, which can affect menstrual regularity, fertility, and premenstrual symptoms. In pregnancy, low progesterone may indicate inadequate support for the uterine lining or early pregnancy complications. In men and postmenopausal women, progesterone is naturally very low and has limited clinical significance.

Optimal progesterone values

Being in range suggests healthy ovulation and adequate corpus luteum function in the second half of the menstrual cycle. Optimal values depend heavily on timing - progesterone should be low in the follicular phase and rise significantly after ovulation during the luteal phase. In pregnancy, rising progesterone supports implantation and placental development. Optimal levels reflect balanced reproductive hormone signaling and stable endometrial support.

High progesterone values

High values usually reflect normal pregnancy, ovulation, or exogenous hormone use such as progesterone supplementation or certain contraceptives. Rarely, elevated progesterone may occur with ovarian cysts or adrenal tumors that produce steroid hormones. Persistent elevation outside of pregnancy or supplementation warrants further investigation.

Factors that influence progesterone interpretation

Progesterone fluctuates dramatically across the menstrual cycle, so timing of the blood draw is critical for accurate interpretation. Pregnancy, hormone therapy, and certain medications all raise levels. Lab methods vary, and single measurements provide limited information without clinical context.

Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.

Subscribe for updates
By clicking “Subscribe” you agree to our Terms and Privacy Policy.
Your content is on its way!
By clicking “Subscribe” you agree to our TOS and Privacy Policy.
Oops! Something went wrong while submitting the form.

Similar biomarker tests from Superpower

See more biomarkers

Frequently Asked Questions

Read more
How it works
What should I expect during a blood draw?
  • A trained phlebotomist will guide you through the process.
  • A tourniquet is placed on your arm, the site is cleaned, and a small needle is used to collect blood into one or more tubes.
  • Results are usually ready in about a week.
  • Most people feel only a quick pinch.
  • The needle is removed, gentle pressure is applied, and a bandage is placed.
How do I prepare for a blood draw?
  • Drink plenty of water beforehand — hydration makes veins easier to find.
  • Wear loose sleeves so your arm is easy to access.
  • Follow any fasting instructions you’ve been given.
  • Let us know if you’re on medications, have fainted before, or have needle anxiety.
What should I do after my blood draw?
  • Press gently on the site for a few minutes.
  • Keep the bandage on for 4-6 hours.
  • Skip heavy lifting or strenuous exercise for the rest of the day.
  • Drink extra water to rehydrate.
  • Monitor the site for redness, swelling, or pain.
How do I book a blood draw with Superpower?

Your membership includes:

  • An annual full body test and report across 100+ biomarkers
  • A personalized action plan to optimize your biomarkers and reach your health goals
  • A dashboard to centralize your health data and track changes across a lifetime
  • Access to a health concierge for questions on your plan and help scheduling
  • Plus a marketplace of curated health products and services cheaper than amazon

Many concierge clinics charge $10k – $100k for their services, we’ve built technology to make the world’s best healthcare as accessible as possible via an all-in-one membership.

Where can I take my blood test?

Superpower is currently available in the following US states:

  • Alabama
  • Arizona
  • California
  • Colorado
  • Connecticut
  • Delaware
  • District of Columbia
  • Florida
  • Georgia
  • Idaho
  • Illinois
  • Indiana
  • Kansas
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • South Carolina
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
Our testing
Does Superpower replace my primary care provider?

Superpower specializes in prevention-based testing and treatments and is not intended for emergency or immediate health issues.

While you will have a Superpower care team, your annual membership is designed to complement a primary care doctor if you have one, not replace them.

We are happy to help you share any test results with an outside provider to ensure you receive well-rounded medical care.

How fast are blood test results and how do I read them?

Your annual lab test panel takes about a week to process. We will text you as soon as they become available in your dashboard. Other types of tests may have different testing windows. The Superpower concierge is your own health assistant who helps answer your questions on your results, ensure smooth scheduling, coordination of any office-based tests, specialist referrals as needed, and navigating you to interface with your care team.

Does Superpower accept health insurance?

Superpower membership and products are all eligible for HSA/FSA funding.

We see Superpower like a gym membership for those committed to prevention and performance. Superpower is a bridge between wellness and healthcare. Health insurance traditionally focuses on reactive care whereas, at Superpower, we believe it’s never too early to start looking out for your long-term health.

What if I want more than 1 blood test per year?

Absolutely — you're not limited to just one. Your membership includes one comprehensive 100+ biomarker blood test each year, but if you'd like to track your progress more closely, you can add extra tests at any time. Each additional full-panel test costs $179. You can order as many as you'd like throughout the year.

“Best health check of my entire life.”

Vinay Hiremath, Founder of Loom

“Life changing”

Jordi Hayes, Founder of Capital.xyz

Frequently Asked Questions about Progesterone Test

What is progesterone and what does it do in the menstrual cycle and pregnancy?

Progesterone is a steroid hormone made mainly by the ovaries after ovulation (by the corpus luteum), with smaller amounts from the adrenal glands and, in pregnancy, the placenta. Its primary role is to prepare and maintain the uterine lining (endometrium) for implantation and early fetal development. Across the menstrual cycle, progesterone rises after ovulation and falls before menstruation, helping regulate bleeding patterns and reproductive timing.

How does progesterone prepare the uterus for implantation and support early pregnancy?

Progesterone transforms the endometrium into a supportive environment for a fertilized egg by thickening the uterine lining, increasing blood flow, and creating conditions that favor implantation. If pregnancy occurs, progesterone remains elevated to maintain the uterine environment and support early development. If pregnancy does not occur, progesterone drops, which helps trigger menstruation. This is why progesterone is closely linked to implantation success and miscarriage risk.

Why is progesterone testing important for confirming ovulation and cycle timing?

Progesterone testing is a key way to confirm whether ovulation occurred in a given cycle because progesterone typically rises after an egg is released. It’s best interpreted alongside cycle timing and symptoms, since levels fluctuate dramatically across the month. A well-timed progesterone blood test can help distinguish between ovulatory and anovulatory cycles and guide next steps for irregular periods, missed cycles, or fertility planning.

When is the best time to test progesterone for accurate results?

Timing is critical for progesterone interpretation. In cycling women, progesterone is usually measured in the mid‑luteal phase - typically about seven days after suspected ovulation - when levels should be higher if ovulation occurred. Testing too early or too late can produce misleading “low” results. Pregnancy, hormone therapy, and certain medications can also alter progesterone levels, so results should be assessed in context with cycle phase and other hormones.

What do low progesterone test results mean if I’m trying to conceive or have irregular periods?

Low progesterone often reflects absent ovulation (anovulation) or weak corpus luteum function, which can contribute to irregular or heavy periods and difficulty conceiving. It may also point to a luteal phase defect that affects endometrial support for implantation. In pregnancy, low progesterone can signal higher miscarriage risk or placental insufficiency. Low progesterone may also contribute to “estrogen dominance” symptoms like mood changes and sleep disruption.

What do high progesterone levels mean, and when are they a concern?

High progesterone is commonly normal in pregnancy, especially in later trimesters when the placenta produces large amounts. Outside pregnancy or the luteal phase, elevated progesterone is less common and may be associated with ovarian cysts, adrenal tumors, congenital adrenal hyperplasia, or certain cancers. Symptoms of high progesterone can include fatigue, bloating, breast swelling, and mood changes. Unexplained high values typically warrant medical evaluation.

How can progesterone testing help with unexplained infertility or difficulty conceiving?

Progesterone testing can clarify whether infertility is related to missed ovulation, poor luteal phase function, or inadequate endometrial support for implantation. By confirming ovulation and assessing corpus luteum function, progesterone results can guide treatment decisions for luteal phase defects and cycle irregularities. Because progesterone works alongside estrogen and other reproductive hormones, it’s often most useful when interpreted with cycle timing, symptoms, and complementary hormone tests.

How is progesterone used to monitor early pregnancy and miscarriage risk?

Progesterone helps maintain the uterine environment needed for early pregnancy. Low progesterone during pregnancy may indicate increased risk of miscarriage, placental insufficiency, or other concerns requiring follow-up. Monitoring progesterone can help flag early pregnancy health issues and inform clinical decisions. However, interpretation depends on gestational timing and overall clinical context, since normal ranges vary by trimester and individual pregnancy dynamics.

Can progesterone affect mood, sleep, and bone health, and how does imbalance show up?

Progesterone influences more than fertility - it also affects mood, sleep architecture, and bone health, and helps balance estrogen’s effects. When progesterone is low, some people experience premenstrual mood swings, anxiety, insomnia, breast tenderness, bloating, and irregular bleeding, especially when estrogen is relatively unopposed. Chronic low progesterone may contribute to reduced bone density over time. Balanced progesterone supports emotional resilience and endocrine stability.

What are common misconceptions about progesterone results (and why context matters)?

A common misconception is that one progesterone number tells the whole story. Progesterone varies dramatically by cycle phase and pregnancy stage, so “low” may simply reflect testing at the wrong time. Another misconception is that progesterone alone explains symptoms; it works with estrogen, thyroid hormones, and cortisol. Stress, thyroid dysfunction, perimenopause, hormone therapy, and medications can all shift levels, so progesterone is best interpreted with timing, symptoms, and related hormones.

Finally, healthcare that looks at the whole you