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LDL P Test

LDL P Test

January 21, 2026
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Do I need a LDL P test?

Struggling with high cholesterol despite eating well, or worried about your heart health even when your standard cholesterol numbers look normal?

LDL P measures the actual number of LDL particles in your blood, not just the cholesterol they carry. This gives you a more accurate picture of your cardiovascular risk than standard cholesterol tests alone.

Testing your LDL P offers a precise snapshot that reveals hidden heart risks standard tests might miss, empowering you to personalize your nutrition, exercise, and treatment plan to truly protect your heart and address those lingering concerns.

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If you’ve been postponing blood testing for years or feel frustrated by doctor appointments and limited lab panels, you are not alone. Standard healthcare is often reactive, focusing on testing only after symptoms appear or leaving patients in the dark.

Superpower flips that approach. We give you full insight into your body with over 100 biomarkers, personalized action plans, long-term tracking, and answers to your questions, so you can stay ahead of any health issues.

With physician-reviewed results, CLIA-certified labs, and the option for at-home blood draws, Superpower is designed for people who want clarity, convenience, and real accountability - all in one place.

Key benefits of LDL P testing

  • Reveals the actual number of LDL particles carrying cholesterol in your blood.
  • Spots cardiovascular risk missed by standard cholesterol panels alone.
  • Explains why some people with normal LDL cholesterol still develop heart disease.
  • Guides precision treatment decisions for statin therapy and lifestyle changes.
  • Tracks how well diet, exercise, or medication reduce your particle burden.
  • Clarifies discordance when LDL cholesterol and non-HDL cholesterol don't align.
  • Best interpreted alongside ApoB and standard lipid panel for complete risk assessment.

What is LDL P?

LDL P (low-density lipoprotein particle number) is a measure of how many LDL particles are circulating in your blood, regardless of how much cholesterol each one carries. Think of it as counting the number of delivery trucks on the road, not just the total cargo they're hauling.

The particle count matters more than you think

Each LDL particle is a tiny sphere that transports cholesterol and fats through your bloodstream to cells that need them. The outer shell is made of proteins and phospholipids, while the core holds cholesterol esters and triglycerides.

More particles mean more chances for trouble

LDL P reflects your actual exposure to atherogenic particles - the ones that can infiltrate artery walls and trigger plaque formation. Two people can have identical LDL cholesterol levels but very different particle counts.

Why counting particles changes the picture

A high particle number means more opportunities for LDL to lodge in arterial walls, even when total cholesterol looks normal. This makes LDL P a more direct marker of cardiovascular risk than cholesterol content alone.

Why is LDL P important?

LDL particle number (LDL P) counts the actual number of LDL cholesterol carriers in your blood, offering a more direct measure of cardiovascular risk than standard cholesterol tests. Each particle can lodge in artery walls and trigger plaque formation, so a higher particle count means more opportunities for damage - even when total LDL cholesterol looks normal. This biomarker reveals how efficiently your liver packages and clears fat, how your vessels respond to injury, and your long-term risk for heart attack and stroke.

More particles mean more risk

Optimal LDL P sits well below 1,000 nmol/L, with lower values strongly linked to healthier arteries. When particle counts rise above 1,200 to 1,400, cardiovascular risk climbs steeply, especially if particles are small and dense. High counts often appear alongside insulin resistance, metabolic syndrome, and inflammation, accelerating plaque buildup in coronary, carotid, and peripheral arteries.

Low counts protect your vessels

Very low LDL P - below 700 nmol/L - reflects efficient lipid clearance and minimal arterial threat. People in this range typically have lower inflammation, better insulin sensitivity, and reduced lifetime cardiovascular events. There are no adverse effects from having too few LDL particles.

The bigger picture

LDL P integrates signals from metabolism, liver function, and vascular health. It predicts heart disease more accurately than LDL cholesterol alone and helps identify hidden risk in people with normal lipid panels. Tracking particle number over time offers insight into how diet, weight, and metabolic health shape your arterial future.

What do my LDL P results mean?

Low LDL particle number

Low values usually reflect reduced production or increased clearance of LDL particles and are generally associated with lower cardiovascular risk. Very low levels may occur with genetic lipid disorders, severe malnutrition, hyperthyroidism, or malabsorption. In most contexts, lower LDL P is considered favorable for vascular health.

Optimal LDL particle number

Being in range suggests balanced lipoprotein metabolism with efficient cholesterol transport and clearance. For cardiovascular risk assessment, optimal typically sits toward the lower end of the reference range. Most evidence supports LDL P below 1000 nmol/L as associated with reduced atherosclerotic risk, though individual targets depend on overall metabolic and inflammatory context.

High LDL particle number

High values usually reflect increased hepatic production of VLDL particles that convert to LDL, reduced LDL receptor activity, or insulin resistance driving overproduction of apoB-containing lipoproteins. Elevated LDL P is strongly associated with increased cardiovascular risk, often more predictive than LDL cholesterol alone. High particle counts frequently accompany metabolic syndrome, type 2 diabetes, and familial hypercholesterolemia.

Factors that influence LDL P levels

LDL particle number rises with age and varies by sex, with premenopausal women typically showing lower values than men. Pregnancy, acute illness, and certain medications including statins and PCSK9 inhibitors significantly alter LDL P. Assay methodology differs across labs, so serial monitoring should use the same platform when possible.

Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.

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Similar biomarker tests from Superpower

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Frequently Asked Questions

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How it works
What should I expect during a blood draw?
  • A trained phlebotomist will guide you through the process.
  • A tourniquet is placed on your arm, the site is cleaned, and a small needle is used to collect blood into one or more tubes.
  • Results are usually ready in about a week.
  • Most people feel only a quick pinch.
  • The needle is removed, gentle pressure is applied, and a bandage is placed.
How do I prepare for a blood draw?
  • Drink plenty of water beforehand — hydration makes veins easier to find.
  • Wear loose sleeves so your arm is easy to access.
  • Follow any fasting instructions you’ve been given.
  • Let us know if you’re on medications, have fainted before, or have needle anxiety.
What should I do after my blood draw?
  • Press gently on the site for a few minutes.
  • Keep the bandage on for 4-6 hours.
  • Skip heavy lifting or strenuous exercise for the rest of the day.
  • Drink extra water to rehydrate.
  • Monitor the site for redness, swelling, or pain.
How do I book a blood draw with Superpower?

Your membership includes:

  • An annual full body test and report across 100+ biomarkers
  • A personalized action plan to optimize your biomarkers and reach your health goals
  • A dashboard to centralize your health data and track changes across a lifetime
  • Access to a health concierge for questions on your plan and help scheduling
  • Plus a marketplace of curated health products and services cheaper than amazon

Many concierge clinics charge $10k – $100k for their services, we’ve built technology to make the world’s best healthcare as accessible as possible via an all-in-one membership.

Where can I take my blood test?

Superpower is currently available in the following US states:

  • Alabama
  • Arizona
  • California
  • Colorado
  • Connecticut
  • Delaware
  • District of Columbia
  • Florida
  • Georgia
  • Idaho
  • Illinois
  • Indiana
  • Kansas
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • South Carolina
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
Our testing
Does Superpower replace my primary care provider?

Superpower specializes in prevention-based testing and treatments and is not intended for emergency or immediate health issues.

While you will have a Superpower care team, your annual membership is designed to complement a primary care doctor if you have one, not replace them.

We are happy to help you share any test results with an outside provider to ensure you receive well-rounded medical care.

How fast are blood test results and how do I read them?

Your annual lab test panel takes about a week to process. We will text you as soon as they become available in your dashboard. Other types of tests may have different testing windows. The Superpower concierge is your own health assistant who helps answer your questions on your results, ensure smooth scheduling, coordination of any office-based tests, specialist referrals as needed, and navigating you to interface with your care team.

Does Superpower accept health insurance?

Superpower membership and products are all eligible for HSA/FSA funding.

We see Superpower like a gym membership for those committed to prevention and performance. Superpower is a bridge between wellness and healthcare. Health insurance traditionally focuses on reactive care whereas, at Superpower, we believe it’s never too early to start looking out for your long-term health.

What if I want more than 1 blood test per year?

Absolutely — you're not limited to just one. Your membership includes one comprehensive 100+ biomarker blood test each year, but if you'd like to track your progress more closely, you can add extra tests at any time. Each additional full-panel test costs $179. You can order as many as you'd like throughout the year.

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Frequently Asked Questions about LDL P Test

What is LDL P (LDL particle number) and how is it different from LDL cholesterol?

LDL P stands for low-density lipoprotein particle number. It measures the total count of LDL particles circulating in your blood, not the amount (weight) of cholesterol inside them like LDL-C does. Each LDL particle is a cholesterol-delivery “vehicle,” and more vehicles mean more chances for cholesterol to enter artery walls. This is why LDL P can reveal cardiovascular risk even when LDL cholesterol looks normal.

Why does LDL P testing reveal hidden cardiovascular risk that a standard lipid panel can miss?

A standard lipid panel focuses on cholesterol content (LDL-C, HDL-C, triglycerides), but it can miss situations where cholesterol is packed into many small particles. LDL P counts the actual number of atherogenic LDL particles that can penetrate artery walls and contribute to plaque. When LDL-C and LDL P are “discordant,” LDL P often better reflects true heart attack and stroke risk over time.

How can my heart risk be high if my LDL cholesterol is normal but LDL P is elevated?

You can have normal LDL-C yet high LDL P when each LDL particle carries less cholesterol, resulting in more particles overall. More LDL particles create more opportunities for arterial wall penetration and plaque formation, independent of cholesterol amount per particle. This pattern is common with insulin resistance, metabolic syndrome, and type 2 diabetes, where small, dense particles tend to circulate longer and raise cardiovascular risk.

What are the key benefits of LDL P testing for prevention and treatment decisions?

LDL P testing reveals your LDL particle burden, helping detect cardiovascular risk earlier than LDL cholesterol alone. It can explain persistent risk despite “normal” LDL-C, clarify discordance with non-HDL cholesterol, and guide precision decisions around statin therapy, lifestyle changes, and other interventions. It’s also useful for tracking how well diet, exercise, or medication lowers particle number over time.

How should LDL P be interpreted alongside ApoB and a standard lipid panel?

LDL P is best interpreted with ApoB and a standard lipid panel for a more complete risk assessment. LDL P counts LDL particles, ApoB reflects the number of atherogenic lipoprotein particles more broadly, and the lipid panel shows cholesterol content and triglyceride patterns. Looking at these together helps clarify metabolic drivers (like insulin resistance) and resolves mismatches between LDL-C, non-HDL cholesterol, and particle-related risk.

What does a high LDL P result mean, and what commonly causes LDL particle counts to climb?

High LDL P indicates an increased number of LDL particles circulating in blood, which raises the probability of plaque formation in artery walls. Common drivers include insulin resistance, metabolic syndrome, and type 2 diabetes, which can increase VLDL production and lead to more small, dense LDL particles. Reduced clearance by LDL receptors can also contribute. High LDL P often progresses silently for years without symptoms.

What does a low LDL P result mean, and is very low LDL P ever a problem?

Low LDL P generally reflects reduced LDL particle production or increased clearance and is often associated with lower cardiovascular risk. It can be seen with very low carbohydrate intake, genetic variants that increase LDL receptor activity, or malabsorption states. Very low LDL P is uncommon; potential underlying causes can include severe malnutrition, advanced liver disease, or rare genetic conditions. Many people with low LDL P have no symptoms.

How do pregnancy, acute illness, and inflammation affect LDL P test results?

LDL P can shift with physiological states. Pregnancy often lowers LDL P early and raises it in the third trimester. Acute illness and inflammation can transiently suppress LDL P, potentially making results look lower than typical baseline. Because these changes can be temporary, LDL P is most informative when interpreted in context with current health status and alongside other lipid markers and metabolic indicators.

How do statins and PCSK9 inhibitors affect LDL P, and how can LDL P track treatment response?

Statins and PCSK9 inhibitors tend to lower LDL P by enhancing receptor-mediated clearance of LDL particles from the bloodstream. LDL P can help track whether treatment is reducing the actual number of atherogenic particles - not just the cholesterol content - over time. Monitoring LDL P alongside the standard lipid panel can show whether medication and lifestyle changes are effectively lowering particle burden and improving cardiovascular risk.

Why do LDL cholesterol and non-HDL cholesterol sometimes not match LDL P, and what is “discordance”?

“Discordance” means cholesterol measures (LDL-C or non-HDL-C) don’t align with particle measures like LDL P. This can happen when particles carry less cholesterol, leading to normal cholesterol numbers but a high particle count. In these cases, LDL P can better represent how many cholesterol-carrying particles are interacting with artery walls. LDL P testing helps clarify risk when standard markers send mixed signals.

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