Get tested with Superpower

If you’ve been postponing blood testing for years or feel frustrated by doctor appointments and limited lab panels, you are not alone. Standard healthcare is often reactive, focusing on testing only after symptoms appear or leaving patients in the dark.

Superpower flips that approach. We give you full insight into your body with over 100 biomarkers, personalized action plans, long-term tracking, and answers to your questions, so you can stay ahead of any health issues.

With physician-reviewed results, CLIA-certified labs, and the option for at-home blood draws, Superpower is designed for people who want clarity, convenience, and real accountability - all in one place.

Key benefits of Apolipoprotein B (ApoB) testing

• Counts the actual number of cholesterol-carrying particles that damage your arteries.
• Spots cardiovascular risk missed by standard cholesterol panels alone.
• Guides precision treatment decisions for heart disease and stroke prevention.
• Tracks how well diet, medication, or lifestyle changes lower your risk.
• Clarifies risk in people with diabetes, metabolic syndrome, or family history.
• Flags hidden danger even when LDL cholesterol looks normal.
• Best interpreted with lipid panel, blood sugar, and cardiovascular symptoms.

What is Apolipoprotein B (ApoB)?

Apolipoprotein B (ApoB) is a large structural protein that sits on the surface of particles that carry fats and cholesterol through your bloodstream. It is made primarily in your liver and intestines. Each particle of LDL (low-density lipoprotein), VLDL (very-low-density lipoprotein), and several other lipoproteins contains exactly one ApoB molecule.

Every particle carries one ApoB molecule

Because each atherogenic particle has one ApoB, measuring ApoB tells you the total number of cholesterol-carrying particles in your blood. This is different from measuring LDL cholesterol, which tells you the amount of cholesterol inside those particles. More particles mean more opportunities for cholesterol to be deposited in artery walls.

ApoB reflects your true particle burden

ApoB is considered a more accurate marker of cardiovascular risk than LDL cholesterol alone. It captures all the potentially harmful particles circulating in your system, including small dense LDL that standard cholesterol tests may underestimate. Elevated ApoB indicates a higher particle count and greater risk for plaque buildup in arteries.

Why is Apolipoprotein B (ApoB) important?

Apolipoprotein B is the structural protein found on every particle that can deposit cholesterol into artery walls - including LDL, VLDL, and remnants. It offers a direct count of atherogenic particles circulating in your blood, making it one of the most accurate predictors of cardiovascular risk. Unlike standard cholesterol tests, ApoB reveals particle number, not just cholesterol content, giving a clearer picture of plaque-building potential.

It counts the particles that matter most

General reference ranges span roughly 40 to 125 mg/dL, but optimal values sit well below 90, and ideally under 80, to minimize long-term arterial damage. Lower ApoB reflects fewer atherogenic particles and reduced cardiovascular threat.

Very low values are uncommon outside of rare genetic conditions or severe malnutrition, where fat absorption or lipoprotein assembly is impaired. These situations may cause fat-soluble vitamin deficiencies and digestive symptoms, though they're clinically rare.

High levels silently accelerate plaque formation

Elevated ApoB means more particles are available to infiltrate vessel walls, even when LDL cholesterol appears normal. This mismatch is common in insulin resistance, metabolic syndrome, and diabetes. Over time, high ApoB drives atherosclerosis in coronary, carotid, and peripheral arteries, raising risk for heart attack and stroke without obvious symptoms until disease is advanced.

A window into lifelong cardiovascular trajectory

ApoB integrates lipid metabolism, insulin sensitivity, and inflammatory tone. It predicts events more reliably than LDL cholesterol alone and helps identify hidden risk in women, younger adults, and those with normal cholesterol but high particle counts.

What do my Apolipoprotein B (ApoB) results mean?

Low ApoB levels

Low values usually reflect reduced production or increased clearance of lipoproteins that carry cholesterol into tissues. This is uncommon and may occur with genetic conditions affecting lipoprotein assembly, severe malnutrition, malabsorption syndromes, or advanced liver disease. Very low ApoB can impair fat-soluble vitamin transport and cellular lipid delivery.

Optimal ApoB levels

Being in range suggests balanced production and clearance of atherogenic lipoproteins. ApoB reflects the total number of LDL, VLDL, and remnant particles capable of entering the arterial wall. Optimal values tend toward the lower end of the reference range, as lower particle counts are associated with reduced cardiovascular risk across populations.

High ApoB levels

High values usually reflect an increased number of cholesterol-carrying particles in circulation, driven by overproduction, reduced clearance, or both. This occurs with insulin resistance, metabolic syndrome, familial hypercholesterolemia, and diets high in saturated fat or refined carbohydrates. Elevated ApoB indicates greater atherogenic burden regardless of LDL cholesterol concentration, as each ApoB molecule represents one potentially harmful particle.

Factors that influence ApoB

ApoB rises with age, obesity, and pregnancy. It is influenced by thyroid function, kidney disease, and medications including statins and PCSK9 inhibitors. ApoB provides a more accurate particle count than calculated LDL cholesterol, especially when triglycerides are elevated or particle size is small.