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Heart & Vascular Health

Blood Testing for Dyslipidemia

Dyslipidemia blood testing reveals how your lipid transport system manages atherosclerosis risk. Superpower offers in-clinic and at‑home testing of LDL, HDL, Triglycerides, ApoB, LDL‑P, HDL‑P, LDL Size, and HDL Size. At‑home Dyslipidemia testing is available in selected states. See FAQs below for more information.

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What are Dyslipidemia biomarkers

Dyslipidemia biomarkers are the measurable fats and the proteins that carry them in blood, revealing how your body transports and disposes of lipids every day. Core measures capture the main cargo (cholesterol and triglycerides) and the vehicles that move it—low-density, high-density, and very-low-density lipoproteins (LDL, HDL, VLDL). The liver builds and recycles most of these particles, while the intestine contributes after meals (chylomicrons). As VLDL sheds triglyceride, it becomes LDL, a particle that can enter artery walls; HDL helps ferry cholesterol back to the liver (reverse cholesterol transport). Protein “tags” on particles add precision: apolipoprotein B reflects the number of artery-entering particles (apoB-containing lipoproteins), apolipoprotein A-I reflects major HDL scaffolding (apoA-I), and a genetically influenced variant, lipoprotein(a), adds a pro-atherogenic component (Lp(a)). Together, these tests map the balance between lipid delivery, storage, and clearance. They enable clinicians to identify harmful traffic patterns in the bloodstream, personalize nutrition and medication choices, and track whether the body’s lipid flow is moving toward arterial safety.

Why is blood testing for Dyslipidemia important?

  • Understand your cholesterol balance and artery-clogging particle load to gauge risk.
  • Spot high ApoB or LDL-P that flags higher heart attack and stroke risk.
  • Reveal hidden risk when LDL looks normal by uncovering small, dense LDL or excess particles.
  • Flag high triglycerides that signal insulin resistance and raise pancreatitis risk.
  • Clarify HDL quality with HDL-P and size to avoid false reassurance from HDL-C.
  • Guide and track therapy using ApoB or LDL-P targets over time.
  • Protect fertility and pregnancy by spotting lipid patterns linked to complications.
  • Prioritize ApoB or LDL-P over particle size when making treatment decisions.

What insights will I get?

Dyslipidemia blood testing provides a window into how your body manages fats, which are essential for energy, hormone production, cell structure, and brain function. Imbalances in blood lipids can disrupt cardiovascular health, metabolism, and even immune and reproductive systems. At Superpower, we measure LDL, HDL, Triglycerides, ApoB, LDL-P, HDL-P, LDL Size, and HDL Size to give a comprehensive view of your lipid profile.

LDL (low-density lipoprotein) is often called “bad cholesterol” because high levels can deposit cholesterol in artery walls, increasing cardiovascular risk. HDL (high-density lipoprotein), or “good cholesterol,” helps remove cholesterol from the bloodstream. Triglycerides are the main form of fat in the blood, reflecting how your body stores and uses energy. ApoB is a protein found on LDL and other atherogenic particles, serving as a direct count of particles that can contribute to plaque buildup. LDL-P and HDL-P measure the number of LDL and HDL particles, while LDL Size and HDL Size describe the average size of these particles, which can influence their behavior in the body.

A stable and healthy lipid profile—characterized by optimal levels and particle sizes—supports resilient blood vessels, efficient energy use, and balanced hormone production. Dyslipidemia, or abnormal lipid levels, can signal increased risk for atherosclerosis, metabolic syndrome, and other systemic imbalances.

Interpretation of these biomarkers can be influenced by factors such as age, sex, pregnancy, acute illness, certain medications, and laboratory methods. These variables are important to consider when assessing lipid health.

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Frequently Asked Questions About

What is Dyslipidemia blood testing?

It measures how fats are carried in your blood and whether those particles promote or protect against artery plaque. Beyond basic cholesterol, it looks at particle number and size, which reflect cardiovascular burden and metabolic health. Superpower tests your blood for LDL, HDL, Triglycerides, ApoB, LDL-P, HDL-P, LDL Size, and HDL Size. LDL and ApoB indicate atherogenic load (particle count). HDL and HDL-P reflect reverse cholesterol transport. Triglycerides signal remnant lipoproteins and insulin resistance. Particle sizes show how triglyceride-rich your system is and whether LDL skews smaller and denser.

Why should I get Dyslipidemia blood testing?

It clarifies your true atherogenic burden and metabolic pattern, not just total cholesterol. ApoB and LDL-P quantify the number of artery-entering particles, the key engine of plaque. Triglycerides and particle sizes uncover insulin resistance and remnant lipoproteins. HDL measures add context for cholesterol efflux. Together, these markers show how your lipid transport system is functioning and refine cardiovascular risk estimation, enabling earlier detection of risk patterns that basic lipids can miss.

Can I get a blood test at home?

Yes. With Superpower, our team member can organize a professional blood draw in your home.

How often should I test?

Get a baseline, then recheck at intervals that track stability or change. Many adults repeat testing annually if stable. When results are changing—after medication changes, major weight shifts, or new diagnoses—testing every 3–12 months is common until the pattern is clear. Advanced markers like ApoB or LDL-P are useful for confirming sustained improvement or detecting silent risk despite “normal” LDL-C. Frequency ultimately depends on overall cardiovascular risk and clinical context.

What can affect biomarker levels?

Recent meals (especially refined carbs and alcohol) raise triglycerides and shift LDL smaller. Acute illness, inflammation, pregnancy, and intense exercise transiently alter values. Medications (statins, fibrates, omega-3s, niacin, steroids, some diuretics), thyroid status, diabetes, kidney or liver disease, and smoking influence particle numbers and composition. Weight change and menopause matter. Genetics (e.g., familial hypercholesterolemia, elevated Lp(a), hypertriglyceridemia variants) can dominate patterns regardless of lifestyle.

Are there any preparations needed before the blood test for LDL, HDL, Triglycerides, ApoB, LDL-P, HDL-P, LDL Size, HDL Size?

Fasting 8–12 hours is recommended (water is fine), especially to stabilize triglycerides and particle metrics, though non‑fasting panels are acceptable in many settings. Avoid alcohol for 24 hours. Take routine medications unless your clinician advises otherwise. Try to test when you’re not acutely ill. Superpower will guide scheduling and collection so your LDL, HDL, Triglycerides, ApoB, LDL-P, HDL-P, LDL Size, and HDL Size are measured under consistent conditions.

Can lifestyle changes affect my biomarker levels?

Yes. Weight change, dietary pattern, alcohol intake, physical activity, sleep, stress, and smoking status can shift triglycerides, HDL, LDL size, and—over time—ApoB/LDL‑P. These inputs influence hepatic lipoprotein production, clearance, and triglyceride exchange, which determines particle number and size. The magnitude and direction vary by genetics and comorbidities.

How do I interpret my results?

Think particle burden first. Higher ApoB or LDL‑P means more atherogenic particles, even if LDL‑C looks “normal.” Triglycerides track remnant lipoproteins and insulin resistance. Smaller, denser LDL and larger VLDL suggest a triglyceride‑rich state; particle number outweighs size for risk. Higher HDL‑P and larger HDL size can indicate stronger reverse cholesterol transport, but function matters more than HDL‑C alone. Integrate these with age, blood pressure, glucose status, smoking, family history, and Lp(a) to understand overall cardiovascular risk.

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