Get tested with Superpower

If you’ve been postponing blood testing for years or feel frustrated by doctor appointments and limited lab panels, you are not alone. Standard healthcare is often reactive, focusing on testing only after symptoms appear or leaving patients in the dark.

Superpower flips that approach. We give you full insight into your body with over 100 biomarkers, personalized action plans, long-term tracking, and answers to your questions, so you can stay ahead of any health issues.

With physician-reviewed results, CLIA-certified labs, and the option for at-home blood draws, Superpower is designed for people who want clarity, convenience, and real accountability - all in one place.

Key benefits of Platelet-to-WBC Ratio testing

• Flags immune system imbalance that may signal inflammation or bone marrow stress.
• Spots early shifts in blood cell production before symptoms become obvious.
• Clarifies unexplained fatigue, bruising, or frequent infections alongside complete blood counts.
• Tracks response to treatment in autoimmune, inflammatory, or hematologic conditions over time.
• Guides decisions about infection risk or clotting concerns in chronic disease management.
• Best interpreted with CBC, CRP, and your clinical symptoms for full context.

What is Platelet-to-WBC Ratio?

The platelet-to-white blood cell ratio is a calculated index that compares the number of platelets to the number of white blood cells (leukocytes) circulating in your bloodstream. Platelets are tiny cell fragments made in the bone marrow that help form clots and stop bleeding. White blood cells are immune cells that defend against infection and inflammation.

Two cell types, one snapshot of balance

This ratio reflects the balance between your clotting system and your immune system. Both cell lines are produced in the bone marrow and released into circulation in response to injury, infection, or stress.

A window into inflammation and immune activation

Changes in this ratio can signal shifts in how your body is responding to illness or injury. A rising white blood cell count during infection or inflammation will lower the ratio, while conditions affecting platelet production or destruction can shift it in the opposite direction.

The ratio offers a simple way to track how these two critical systems are behaving relative to each other over time.

Why is Platelet-to-WBC Ratio important?

The platelet-to-white blood cell ratio offers a window into how your immune system and clotting machinery are balanced. It reflects whether your bone marrow is producing blood cells in healthy proportion and whether inflammation, infection, or immune dysregulation is tipping that balance. A typical ratio ranges from about 15 to 40, with values in the middle suggesting steady-state production and immune calm.

When the ratio drops below normal

A low ratio means white cells are rising faster than platelets, or platelets are falling. This pattern appears during acute infections, autoimmune flares, or bone marrow stress when the body ramps up immune cell production. You may feel fatigued, feverish, or notice easy bruising if platelet counts are also declining.

When the ratio climbs above normal

A high ratio signals that platelets are elevated relative to white cells, often seen in chronic inflammation, iron deficiency, or after spleen removal. It can also reflect a muted immune response or recovery from infection. Elevated platelets may increase clotting risk, though symptoms are often subtle until a clot forms.

The bigger picture of immune and clotting balance

This ratio connects bone marrow health, immune activation, and thrombotic risk into a single snapshot. Persistent imbalance may point to underlying inflammatory disease, nutritional deficits, or hematologic disorders. Tracking it over time helps reveal whether your body is maintaining equilibrium or signaling a need for deeper investigation.

What do my Platelet-to-WBC Ratio results mean?

Low platelet-to-WBC ratio

Low values usually reflect either a drop in platelet production or a rise in white blood cell count. This pattern is common during active infection, inflammation, or immune activation when the bone marrow ramps up white cell output. It can also occur when platelet production is suppressed by medications, nutritional deficiencies, or bone marrow disorders. In chronic inflammatory states or autoimmune conditions, both processes may coexist, driving the ratio downward.

Optimal platelet-to-WBC ratio

Being in range suggests balanced bone marrow output and stable immune-inflammatory tone. Most healthy adults maintain a ratio between 20 and 50, reflecting steady platelet turnover and a baseline white cell population appropriate for routine immune surveillance. This balance supports normal clotting capacity without excessive inflammatory signaling.

High platelet-to-WBC ratio

High values usually reflect elevated platelet counts or reduced white blood cell numbers. Reactive thrombocytosis from iron deficiency, tissue injury, or chronic inflammation can push the ratio upward. Conversely, a low white cell count due to viral suppression, certain medications, or bone marrow fatigue will have the same effect. Rarely, primary bone marrow disorders cause disproportionate platelet elevation.

Factors that influence platelet-to-WBC ratio

Pregnancy, acute illness, recent surgery, and corticosteroid use all shift this ratio. Age-related changes in marrow reserve and chronic low-grade inflammation also play a role. Interpretation requires context from absolute platelet and white cell counts, not the ratio in isolation.