Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time. Derived from laboratory results. This score or index is not an FDA-cleared test. It aids clinician-directed assessment and is not a stand-alone diagnosis.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Hydrogen sulfide index testing
- Gut hydrogen sulfide production capacity tracking
- colonic gas and potential mucosa-relevant compound monitoring
What is Hydrogen sulfide index?
The Hydrogen sulfide index is a derived metric estimating the capacity of your gut microbiome to produce hydrogen sulfide (H2S) gas. Calculated from the abundance of sulfate-reducing bacteria and H2S-producing genes detected by shotgun sequencing.
Why is Hydrogen sulfide index important?
Hydrogen sulfide is a gut-produced gas with complex effects - at low levels it may have signaling roles, but at higher levels it may have cytotoxic effects on colonocytes and contribute to intestinal inflammation in some contexts. Monitoring H2S production capacity provides a functional metabolic snapshot.
What insights will I get?
Your Hydrogen sulfide index may indicate the degree to which your gut microbiome is set up for H2S production. Elevated levels alongside other inflammation markers may be worth reviewing with your care team in the context of any bowel symptoms.





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