Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time. Derived from laboratory results. This score or index is not an FDA-cleared test. It aids clinician-directed assessment and is not a stand-alone diagnosis.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Hexa-LPS index testing
- Pro-inflammatory lipopolysaccharide burden tracking
- gut-driven systemic inflammation assessment
What is Hexa-LPS index?
The Hexa-LPS index is a derived metric estimating the relative abundance of gut bacteria producing pro-inflammatory hexa-acylated lipopolysaccharides (LPS) - a potent form of bacterial endotoxin. Calculated from metagenomically identified bacteria with pro-inflammatory LPS profiles.
Why is Hexa-LPS index important?
Hexa-acylated LPS is the most pro-inflammatory form of bacterial endotoxin. Gut bacteria with high hexa-LPS content may contribute to low-grade systemic inflammation when gut barrier integrity is compromised. Monitoring this index may provide a proxy for gut-derived inflammatory burden.
What insights will I get?
Your Hexa-LPS index may indicate the inflammatory potential of your gut microbial community. Elevated scores alongside indicators of gut barrier disruption may suggest a microbiome profile associated with increased endotoxin-driven inflammatory burden.
.svg)
.avif)
.avif)
