Get tested with Superpower

If you’ve been postponing blood testing for years or feel frustrated by doctor appointments and limited lab panels, you are not alone. Standard healthcare is often reactive, focusing on testing only after symptoms appear or leaving patients in the dark.

Superpower flips that approach. We give you full insight into your body with over 100 biomarkers, personalized action plans, long-term tracking, and answers to your questions, so you can stay ahead of any health issues.

With physician-reviewed results, CLIA-certified labs, and the option for at-home blood draws, Superpower is designed for people who want clarity, convenience, and real accountability - all in one place.

Key benefits of Gamma-Glutamyl Transferase (GGT) testing

• Spot early liver stress before symptoms appear or other tests turn abnormal.
• Flag bile duct blockage when paired with elevated alkaline phosphatase levels.
• Clarify whether high alkaline phosphatase comes from liver or bone disease.
• Track alcohol-related liver damage and monitor progress during recovery or treatment.
• Detect medication side effects that quietly strain your liver over time.
• Guide decisions about imaging or biopsy when liver disease is suspected.
• Explain fatigue, jaundice, or abdominal pain tied to bile flow problems.
• Best interpreted with ALT, AST, and alkaline phosphatase for complete liver assessment.

What is Gamma-Glutamyl Transferase (GGT)?

Gamma-glutamyl transferase is an enzyme found in the membranes of cells throughout your body, with the highest concentrations in the liver, bile ducts, kidneys, and pancreas. It belongs to a family of proteins that help move molecules across cell boundaries and break down larger compounds into usable parts.

GGT guards the gateway to your cells

GGT sits on the outer surface of cells, where it plays a key role in managing glutathione, one of your body's most important antioxidants. It breaks down glutathione in the bloodstream so that its building blocks, especially the amino acid cysteine, can be absorbed and recycled by cells.

A window into liver and bile duct health

Because GGT is especially abundant in liver and bile duct cells, it spills into the bloodstream when these tissues are stressed, inflamed, or damaged. This makes it a sensitive marker of liver cell activity and bile flow.

It responds to more than just alcohol

While GGT rises with alcohol consumption, it also increases with medications, obesity, oxidative stress, and various forms of liver or bile duct irritation.

Why is Gamma-Glutamyl Transferase (GGT) important?

Gamma-glutamyl transferase is an enzyme found primarily in the liver, bile ducts, and kidneys that helps process glutathione, your body's master antioxidant. Elevated GGT signals stress on the liver and biliary system, often appearing before other liver enzymes rise. It's especially sensitive to alcohol use, fatty liver, and bile flow obstruction, making it a key early-warning marker for metabolic and hepatic health.

When GGT stays in the normal range

Typical values generally fall between 10 and 50, though optimal levels tend to sit toward the lower end of this range. Lower GGT reflects efficient liver detoxification, healthy bile flow, and minimal oxidative stress. Very low values are uncommon and rarely clinically significant, though they may appear in individuals with excellent metabolic health and minimal liver burden.

What rising GGT reveals about your liver and metabolism

Elevated GGT most often points to liver cell stress, bile duct inflammation, or alcohol-related damage, even in the absence of symptoms. It rises with fatty liver disease, chronic alcohol use, medication toxicity, and biliary obstruction. High levels correlate with increased cardiovascular and metabolic disease risk, independent of other liver markers.

The bigger metabolic picture

GGT connects liver health to oxidative stress, inflammation, and insulin resistance across multiple organ systems. Persistently elevated levels predict long-term risks including diabetes, heart disease, and chronic liver disease, making it a valuable window into whole-body metabolic resilience.

What do my Gamma-Glutamyl Transferase (GGT) results mean?

Low GGT values

Low values usually reflect minimal enzyme activity in the bile ducts and liver cells, which is generally favorable. GGT is not typically elevated by muscle or bone turnover, so low levels simply indicate an absence of biliary stress or hepatocellular injury. Very low values have no known clinical significance and are not associated with disease states.

Optimal GGT values

Being in range suggests that bile flow is unobstructed and that liver cells are not under oxidative or toxic stress. Optimal values tend to sit toward the lower end of the reference range, as even high-normal GGT can reflect subclinical inflammation or alcohol exposure. Stable, low-normal GGT supports healthy hepatobiliary and metabolic function.

High GGT values

High values usually reflect increased enzyme production in response to bile duct obstruction, liver cell injury, or oxidative stress. GGT rises with alcohol use, fatty liver disease, cholestasis, and certain medications. It is more sensitive than other liver enzymes to biliary tract disease and can be elevated in metabolic syndrome, even when other liver markers remain normal. Men typically have slightly higher baseline GGT than women.

Notes on interpretation

GGT is influenced by alcohol intake, obesity, diabetes, and medications including phenytoin and barbiturates. It rises during acute illness and can remain elevated in chronic liver conditions. Pregnancy does not significantly affect GGT, unlike alkaline phosphatase.