Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time. Derived from laboratory results. This score or index is not an FDA-cleared test. It aids clinician-directed assessment and is not a stand-alone diagnosis.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of GABA breakdown testing
- Gut microbial GABA degradation capacity tracking
- gut-brain axis GABA net availability assessment
What is GABA breakdown?
This metric estimates your gut microbiome's functional capacity to degrade GABA, derived from the abundance of GABA transaminase and related catabolic enzyme-encoding genes detected by shotgun metagenomic sequencing.
Why is GABA breakdown important?
GABA degradation capacity complements GABA production capacity to provide a net picture of gut GABA metabolism. A high breakdown capacity relative to production may indicate reduced net gut GABA availability from microbial sources.
What insights will I get?
Your GABA breakdown capacity - interpreted alongside GABA production capacity - may provide a view of net gut microbial GABA metabolism. This emerging area of gut-brain research may become more interpretively rich as the field develops.
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