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Albumin Test

Albumin Test

January 21, 2026
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Do I need an Albumin test?

Feeling unusually tired, noticing swelling in your legs or ankles, or concerned about unexplained weight changes? Could low albumin be affecting your body's ability to maintain fluid balance and transport vital nutrients?

Albumin is the most abundant protein in your blood, playing a crucial role in maintaining fluid balance, transporting hormones and nutrients, and supporting overall tissue health. Low levels can signal liver or kidney issues, malnutrition, or inflammation.

Testing your albumin gives you a vital snapshot of your liver function, nutritional status, and protein balance. It's a key first step to understanding what's behind your fatigue or swelling and personalizing your nutrition and lifestyle to restore balance.

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Get tested with Superpower

If you’ve been postponing blood testing for years or feel frustrated by doctor appointments and limited lab panels, you are not alone. Standard healthcare is often reactive, focusing on testing only after symptoms appear or leaving patients in the dark.

Superpower flips that approach. We give you full insight into your body with over 100 biomarkers, personalized action plans, long-term tracking, and answers to your questions, so you can stay ahead of any health issues.

With physician-reviewed results, CLIA-certified labs, and the option for at-home blood draws, Superpower is designed for people who want clarity, convenience, and real accountability - all in one place.

Key benefits of Albumin testing

  • Measures your liver's ability to produce essential protein for health.
  • Spots early liver stress before symptoms like fatigue or swelling appear.
  • Flags malnutrition or protein loss that weakens immunity and healing.
  • Explains unexplained swelling in legs, ankles, or abdomen.
  • Guides treatment for chronic kidney disease by tracking protein loss.
  • Tracks recovery after surgery, infection, or critical illness.
  • Best interpreted with liver enzymes, total protein, and your symptoms.

What is Albumin?

Albumin is the most abundant protein in your blood, made continuously by your liver and released into circulation. It's a small, sturdy molecule that accounts for roughly half of all the protein floating in your plasma.

Your blood's multitasking workhorse

Albumin serves as the body's master transporter and fluid regulator. It ferries hormones, vitamins, drugs, and fatty acids to tissues that need them. At the same time, it acts like a sponge, holding water inside your blood vessels through osmotic pressure. Without enough albumin, fluid leaks into tissues, causing swelling.

A window into liver and kidney health

Because albumin is produced only by the liver and filtered carefully by the kidneys, its blood level reflects how well both organs are functioning. It also responds to inflammation, nutrition, and chronic illness. Measuring albumin gives clinicians a snapshot of your body's protein balance and overall physiological resilience.

Why is Albumin important?

Albumin is the most abundant protein in your blood, manufactured exclusively by your liver and released into circulation to hold fluid inside your vessels, ferry hormones and nutrients to tissues, and buffer acids throughout your body. When albumin levels fall outside the typical range of roughly 3.5 to 5.5, it signals that your liver, kidneys, nutritional state, or inflammatory burden may be compromised. Optimal values usually sit in the mid-to-upper portion of the range, reflecting robust liver synthesis and minimal protein loss.

When albumin drops, fluid escapes

Low albumin means your blood cannot hold water effectively, so fluid leaks into tissues and body cavities, causing swelling in the legs, abdomen, or lungs. This happens with chronic liver disease, kidney damage that spills protein into urine, severe malnutrition, or prolonged inflammation from infection or autoimmune conditions. Fatigue, poor wound healing, and susceptibility to infection often follow because albumin also transports immune molecules and micronutrients.

High albumin usually reflects dehydration

Elevated albumin is rarely a primary disease but instead points to concentrated blood from dehydration or severe fluid loss. It can also appear transiently during acute stress or hemoconcentration.

The big picture

Albumin integrates liver function, kidney integrity, nutritional reserves, and systemic inflammation into a single number. Persistent abnormalities predict higher risks for hospitalization, slower recovery from illness, and poorer long-term outcomes across cardiovascular, metabolic, and immune health.

What do my Albumin results mean?

Low albumin usually reflects reduced production or increased loss

Low values usually reflect either inadequate synthesis by the liver or excessive loss through the kidneys or gut. Chronic liver disease, malnutrition, and inflammatory states all suppress albumin production. Protein-losing conditions such as nephrotic syndrome or protein-losing enteropathy drain albumin from circulation. Low albumin reduces oncotic pressure, which can lead to fluid shifts into tissues and contribute to edema or ascites. It also impairs nutrient transport and drug binding, affecting how medications behave in the body.

Optimal albumin suggests healthy liver function and protein balance

Being in range suggests that your liver is synthesizing protein efficiently and that you are not losing excessive albumin through kidneys or intestines. Optimal values typically sit in the mid to upper portion of the reference range and reflect stable hydration, adequate protein intake, and low systemic inflammation. This supports normal fluid distribution, nutrient transport, and overall metabolic resilience.

High albumin usually reflects dehydration

High values usually reflect dehydration or hemoconcentration rather than true overproduction. When plasma volume contracts, albumin concentration rises. This is common with inadequate fluid intake, vomiting, diarrhea, or diuretic use.

Context matters for accurate interpretation

Albumin declines naturally with age and during acute illness or surgery due to inflammation. Pregnancy lowers albumin through hemodilution. Results should always be interpreted alongside hydration status, liver function, kidney health, and inflammatory markers.

Method: FDA-cleared clinical laboratory assay performed in CLIA-certified, CAP-accredited laboratories. Used to aid clinician-directed evaluation and monitoring. Not a stand-alone diagnosis.

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Frequently Asked Questions

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How it works
What should I expect during a blood draw?
  • A trained phlebotomist will guide you through the process.
  • A tourniquet is placed on your arm, the site is cleaned, and a small needle is used to collect blood into one or more tubes.
  • Results are usually ready in about a week.
  • Most people feel only a quick pinch.
  • The needle is removed, gentle pressure is applied, and a bandage is placed.
How do I prepare for a blood draw?
  • Drink plenty of water beforehand — hydration makes veins easier to find.
  • Wear loose sleeves so your arm is easy to access.
  • Follow any fasting instructions you’ve been given.
  • Let us know if you’re on medications, have fainted before, or have needle anxiety.
What should I do after my blood draw?
  • Press gently on the site for a few minutes.
  • Keep the bandage on for 4-6 hours.
  • Skip heavy lifting or strenuous exercise for the rest of the day.
  • Drink extra water to rehydrate.
  • Monitor the site for redness, swelling, or pain.
How do I book a blood draw with Superpower?

Your membership includes:

  • An annual full body test and report across 100+ biomarkers
  • A personalized action plan to optimize your biomarkers and reach your health goals
  • A dashboard to centralize your health data and track changes across a lifetime
  • Access to a health concierge for questions on your plan and help scheduling
  • Plus a marketplace of curated health products and services cheaper than amazon

Many concierge clinics charge $10k – $100k for their services, we’ve built technology to make the world’s best healthcare as accessible as possible via an all-in-one membership.

Where can I take my blood test?

Superpower is currently available in the following US states:

  • Alabama
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Our testing
Does Superpower replace my primary care provider?

Superpower specializes in prevention-based testing and treatments and is not intended for emergency or immediate health issues.

While you will have a Superpower care team, your annual membership is designed to complement a primary care doctor if you have one, not replace them.

We are happy to help you share any test results with an outside provider to ensure you receive well-rounded medical care.

How fast are blood test results and how do I read them?

Your annual lab test panel takes about a week to process. We will text you as soon as they become available in your dashboard. Other types of tests may have different testing windows. The Superpower concierge is your own health assistant who helps answer your questions on your results, ensure smooth scheduling, coordination of any office-based tests, specialist referrals as needed, and navigating you to interface with your care team.

Does Superpower accept health insurance?

Superpower membership and products are all eligible for HSA/FSA funding.

We see Superpower like a gym membership for those committed to prevention and performance. Superpower is a bridge between wellness and healthcare. Health insurance traditionally focuses on reactive care whereas, at Superpower, we believe it’s never too early to start looking out for your long-term health.

What if I want more than 1 blood test per year?

Absolutely — you're not limited to just one. Your membership includes one comprehensive 100+ biomarker blood test each year, but if you'd like to track your progress more closely, you can add extra tests at any time. Each additional full-panel test costs $179. You can order as many as you'd like throughout the year.

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Frequently Asked Questions about Albumin Test

What is albumin in a blood test and what does it do in the body?

Albumin is the most abundant protein in your blood plasma, making up roughly half of circulating protein. It’s made exclusively by the liver and released continuously. Albumin’s key jobs are maintaining fluid balance (keeping water inside blood vessels to prevent leakage into tissues) and transporting “cargo” like hormones, fatty acids, vitamins, and many medications. It also helps buffer pH and supports overall tissue repair and resilience.

Why would my doctor order an albumin test for liver, kidney, or nutrition concerns?

Albumin testing helps assess your liver’s ability to produce essential protein, detect early liver stress before symptoms, and flag malnutrition or protein loss that can weaken immunity and wound healing. It can also help explain swelling (legs, ankles, abdomen) and guide chronic kidney disease monitoring by tracking protein loss. Results are best interpreted alongside liver enzymes, total protein, and your symptoms for a clearer clinical picture.

What is the normal albumin range and what do albumin levels outside 3.5–5.5 g/dL mean?

Typical albumin reference ranges are roughly 3.5–5.5 g/dL. Levels below range often suggest reduced liver production, increased protein loss (kidneys or gut), inflammation, or dilution from fluid retention. Levels above range are uncommon and usually reflect dehydration (hemoconcentration), not true overproduction. Because lab methods and health status can affect results, trends over time and related tests (liver enzymes, total protein) are often more informative than one value.

What are the most common causes of low albumin (hypoalbuminemia) in adults?

Low albumin usually reflects one or more of: decreased liver synthesis (chronic liver disease), poor protein intake or severe malnutrition, inflammation or acute illness suppressing production, protein loss through damaged kidneys (proteinuria), or loss through the gut (protein-losing enteropathy). Fluid overload can also “dilute” albumin. Low albumin reduces oncotic pressure, making swelling more likely, and can impair transport of hormones, nutrients, and drugs throughout the body.

How does low albumin cause swelling in legs, ankles, or the abdomen (edema/ascites)?

Albumin acts like a sponge that helps hold water inside blood vessels by maintaining oncotic pressure. When albumin is low, fluid is more likely to leak from blood vessels into surrounding tissues or body cavities. This can show up as leg or ankle swelling (edema) or abdominal fluid buildup (ascites). Low albumin can also accompany conditions that cause fluid retention, making swelling more noticeable and sometimes appearing before other symptoms.

Can dehydration cause high albumin results, and does high albumin mean disease?

Yes - high albumin is most often due to dehydration or hemoconcentration, where reduced plasma volume makes albumin appear elevated. Vomiting, diarrhea, or inadequate fluid intake can cause mild increases. True overproduction of albumin does not occur. Rehydration typically normalizes the value. If albumin stays high, it’s usually a cue to reassess hydration and overall fluid balance and consider related kidney function evaluation.

How should albumin results be interpreted with liver enzymes and total protein?

Albumin is most meaningful when interpreted with liver enzymes, total protein, and symptoms because it reflects multiple systems: liver production, kidney and gut protein loss, and inflammation or fluid status. Normal albumin alongside abnormal liver enzymes can still indicate liver stress, while low albumin with proteinuria points more toward kidney loss. Total protein helps contextualize whether low albumin is part of broader protein changes. Monitoring trends improves accuracy versus relying on a single lab value.

How can pregnancy, aging, surgery, or infection affect albumin levels on lab tests?

Albumin can decrease modestly with aging and commonly drops during pregnancy due to plasma volume expansion (a dilution effect). Acute illness, infection, surgery, and inflammation can temporarily suppress albumin synthesis, lowering results even without chronic liver disease or malnutrition. Because these are common, short-term influences, repeating the test and watching trends over time can provide a better signal of true nutritional status, organ reserve, and recovery progress than one isolated measurement.

Does low albumin affect medications, calcium, or thyroid hormones in bloodwork?

Yes. Albumin binds and carries many medications as well as hormones and nutrients. When albumin is low, the transport and “bound vs. free” balance of certain substances can shift, which may influence drug effectiveness and interpretation of labs that interact with albumin. The context notes albumin binding with thyroid hormone and calcium, meaning low albumin can indirectly affect energy, bone-related markers, and medication handling. Clinicians often interpret related tests with albumin in mind.

How is albumin testing used to track recovery after surgery or critical illness and guide long-term risk?

Albumin can help track recovery after surgery, infection, or critical illness because inflammation and stress can lower synthesis and increase losses. Persistently low albumin correlates with higher hospitalization risk, slower healing, and higher long-term mortality, reflecting reduced organ reserve, nutrition gaps, or ongoing inflammation. Tracking albumin over time helps reveal whether your body is rebuilding protein reserves and maintaining fluid balance - especially when reviewed with symptoms and complementary labs.

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