Superpower vs Empirical Health

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Superpower Logo
Empirical Health
Annual baseline test
150+ lab tests across two draws*
100 biomarkers on one draw, sold as a heart health program*
Testing locations
2,000+ partner labs or at-home draw (+$119)
2,000+ partner labs
New York and New Jersey access
+$250 to cover state fees
+$99 lab fee
Follow-up test
Partial redraw retesting ~60 biomarkers, included
Repeat testing at 3 and 9 months on the $399 program; none on the $190 panel
Results turnaround
Within 10 days of the draw
Most results in 3-5 business days, complete results in 2-3 weeks
Action plan
Superpower Protocol, built from labs, wearables, and medical records
Physician-interpreted report, plus custom nutrition and exercise plans
AI insights
Personalized insights, recommendations, and guidance based on labs, wearables, and more
AI-powered food recognition for meal logging, with DASH-aligned meal suggestions
AI + care team support
Wearable integration
Curated supplement marketplace with member-exclusive pricing
Not included
Access to prescription medications
Through the marketplace, when clinically appropriate
Through the doctor visit in the $399 Advanced program
Lp(a) testing
Add-on
Included
Cost
$349$199
$190 one-time panel, or $399 for the 12-month Advanced program
Start testing

*Includes direct laboratory measurements and calculated health metrics. Superpower's count combines an initial draw with a partial follow-up draw that repeats around 60 of the same markers. Empirical Health's count is its own published list for one draw, which places 85 lab results alongside heart-attack risk estimates, dietary-intake metrics, and app scores. Comparison based on publicly available information as of 10/2/2026.

IMPORTANT: For a limited time, a Superpower membership is only $199 per year. Get the same value - 150+ blood tests, an AI companion, supplement marketplace, and more - at an even lower price point.

Key takeaway:

Empirical Health ($190 one-time) is a heart health company that tests 100 biomarkers, including ApoB and Lp(a), in a single lab visit, with heart-attack risk estimates and nutrition and exercise plans. If you want more than a heart check, Superpower ($349/yr) goes beyond biomarker testing to be a true home for health. Alongside 150+ lab tests across two draws, it adds a member marketplace for supplements, prescriptions, and add-on tests. Superpower's AI works from all of that data, returning personalized insights, health coaching, and a complete action plan.
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What is Superpower, and what is Empirical Health?

Built to be a home for health, Superpower is an all-in-one health platform. Your yearly membership covers AI health coaching, wearable data tracking, biomarker testing, and a personalized action plan, plus a marketplace of member-exclusive supplements and add-on tests, with prescriptions available when clinically appropriate, priced separately.

Empirical Health is a heart health company. Its homepage leads with "Don't die of heart disease," and its model runs on three words: "measure," "predict," and "prevent." Its testing starts with a $190 panel of 100 biomarkers, drawn in one lab visit.

Both start from a wide blood panel. They diverge on how much of your health the membership is built around, and on where you act on the results.

What does Superpower include?

Your $349 yearly membership includes 150+ lab tests across two draws, AI + care team support, a personalized action plan, wearable and medical record integration, and a marketplace of member-exclusive supplements and add-on tests.

Here is the simple path from joining to results:

  1. Join for $349 a year.
  2. Sync your wearables and add AI chats, earlier lab results, and any medical records you already have.
  3. Book your first blood draw at a lab, or pay an extra $119 for a home visit.
  4. Your results appear as health metrics in the dashboard within 10 days.
  5. After that, your first Superpower Protocol turns those metrics into an action plan that covers lifestyle changes, supplements, and more.
  6. Whenever you need help, AI + care team support is there.
  7. Partway through the year, the follow-up draw already built into your membership retests around 60 key trackable markers.

Your dashboard builds a digital twin from that data, a 3D model of your metrics. Records, wearable data, and earlier lab results you upload begin producing insights before your first draw is even processed.

Every membership comes with two scores. Your Superpower Score tracks how close you are to optimal across every biomarker, while your biological age rolls your whole body up into a single number. Both update after each follow-up draw, so you can see what is moving.

Whatever the results show, you can act on them in that same place. The member marketplace carries add-on panels and scans, plus supplements at up to 20% off and prescriptions available when clinically appropriate, priced separately.

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What does Empirical Health include?

Empirical Health sells two heart health programs. The Comprehensive Heart Health panel costs $190, paid once, and includes 100 biomarkers in a single lab visit, in-app heart health risk scores and monitoring, and full access to Empirical Pro, with premium metric tracking and historical data. The 12-Month Advanced Heart Health Program costs $399 and adds custom repeat testing at 3 and 9 months and a video visit with a board-certified doctor.

Empirical Health publishes a three-step process:

  1. "Measure" — Drop into a testing site to track 100+ high-signal biomarkers, such as ApoB, Lp(a), and cholesterol.
  2. "Predict" — See how your risk of heart disease will change over your lifetime, based on your biomarkers, and toggle lifestyle choices to see the effect.
  3. "Prevent" — Get a nutrition and exercise plan tailored to you, and snap a picture of your food to track it.

Results arrive with a physician-interpreted report that explains what your numbers mean and what actions you can take. Through the app and web app, members can also message Empirical's doctors and upload past blood test results to compare against new ones.

What biomarkers do Superpower and Empirical Health measure in 2026?

Superpower's membership opens with 150+ lab tests across two draws, a targeted set. Empirical Health publishes 100 biomarkers on one draw. Its list counts 85 lab results alongside two heart-attack risk estimates, nine dietary-intake metrics, and four app scores, such as a sleep apnea screen.

SuperpowerEmpirical Health
Initial draw87 biomarkers (75 distinct and 12 calculated)85 lab biomarkers (72 distinct and 13 calculated)
Follow-up drawRetests ~60 markers already on the initial panel, includedCustom repeat testing at 3 and 9 months on the $399 program; none on the $190 panel
Headline count150+ lab tests across two draws100 biomarkers in a single draw

Empirical's list does not say which markers are calculated, so we counted them. There are 13, including non-HDL cholesterol and the ApoB/ApoA1 ratio. Both lab counts include urinalysis, and on that basis the two initial draws are close.

Empirical's list includes a handful of markers missing from Superpower's initial draw, such as Lp(a), ApoA1, vitamin B12, and folate. Superpower's initial draw adds insulin, cortisol, and sex hormones such as testosterone and estradiol. Length alone does not make testing better. Measuring the right markers for you is what changes your decisions.

On top of the membership, Superpower's marketplace sells these add-ons:

  • Advanced scans — DEXA body composition and DEXA bone density, along with a heart calcium scan, VO2 max, and a whole-body MRI from Prenuvo.
  • Brain and cognitive health — Testing for amyloid plaque and tau protein, along with ApoE genetic risk screening.
  • Specialty screening — Whole genome sequencing and gut microbiome analysis, along with an organ age panel.
  • Hormone and reproductive health — Egg reserve and active testosterone testing, plus prostate screening and sperm analysis.
  • Toxins and nutrition — Tests for environmental toxins, heavy metals, and mycotoxins, along with methylation, mineral, vitamin, and organic acids panels.

What are the official 2026 membership prices for Superpower and Empirical Health?

Superpower costs $349 a year. Empirical Health's panel costs $190, paid once, and its 12-month Advanced program costs $399.

For a single draw, Empirical's $190 panel is the lower price, with no built-in retest. Superpower's $349 includes both draws and the action plan.

State fees apply in New York and New Jersey, which puts membership at $599 a year. An at-home draw adds $119 on Superpower. Empirical adds a $99 lab fee in New York and New Jersey, for $289 in total.

Superpower add-on panels, tests, and scans carry an extra cost. Pre-tax HSA or FSA dollars work for either company, as both are eligible.

How do Superpower and Empirical Health cover heart health?

Empirical Health is built around your heart, while Superpower includes the core heart markers in a broader panel. Heart depth is Empirical's real strength.

Empirical's single draw carries ApoB, Lp(a), hs-CRP, and HbA1c, a full lipid panel with four cholesterol ratios, and ApoA1 with the ApoB/ApoA1 ratio. It also estimates your 10-year and lifetime heart-attack risk, and its nutrition tracking follows sodium, potassium, fiber, and saturated fat.

Superpower's initial draw includes the core heart and metabolic markers: ApoB, hs-CRP, HbA1c, insulin, and a lipid panel with ratios. The follow-up draw repeats the lipid panel, HbA1c, and hs-CRP later in the year, inside the price. Lp(a) is a separate marketplace purchase, the Lipoprotein (a) Add-on. A Heart Calcium Scan can be booked the same way.

Superpower reads heart health alongside hormones, thyroid, kidney and liver function, and blood counts, so one protocol draws on all of it.

Superpower vs Empirical Health: care, coaching, and AI

Empirical Health's care runs through physicians.

Every Empirical result comes with a physician-interpreted report. The $399 Advanced program adds a video consultation with a board-certified doctor, who reviews your results, creates a personalized care plan, and discusses any prescriptions or referrals you may need. If a doctor visit is what you want, that program is built for it.

Empirical's AI works on daily habits. Its app logs meals with AI-powered food recognition, suggests DASH-aligned meals, and builds exercise plans. Its supported wearables include Apple Watch, Google Pixel Watch, Samsung Galaxy Watch, and Fitbit devices, though a wearable is optional.

The plan comes straight from Superpower AI, which writes and revises your protocol against lab results, wearable data synced from Apple Health, Whoop, Oura, and more, medications, medical history, and any context you add. Personalized AI health coaching is available on demand, with no visit to book.

Get 150+ lab tests, in-lab or at home

One membership, two built-in draws. Get a full picture of your health and the action plan you need to improve it.

Book your test

Where are Superpower and Empirical Health tests available?

Members in 41 states and Washington, D.C. can test through 2,000+ partner lab locations, with at-home draws offered in most regions. Launch is still ahead in Alaska, Arkansas, Hawaii, Louisiana, Mississippi, North Dakota, Rhode Island, South Dakota, and Wyoming.

Empirical Health also draws at 2,000+ partner labs, where members can walk in or book ahead. Its app can be used anywhere, while its medical services reach people in over 30 states.

Comparing member marketplaces

Joining unlocks a member-exclusive marketplace of add-on tests and supplements, where supplements are discounted up to 20% and prescriptions are available when clinically appropriate, priced separately.

Empirical Health does not offer a supplement marketplace. Prescriptions come through the doctor visit in the $399 Advanced program.

Who is Superpower best for, and who is Empirical Health best for?

Superpower is best for:

  • People who want one all-in-one health platform instead of a heart check alone.
  • People who want hormone, thyroid, and metabolic markers alongside core heart markers, with a follow-up draw included.
  • People who want AI-powered coaching that personalizes insights from every metric they track.
  • People who want add-on tests, scans, supplements, and prescription access all within one membership.

Empirical Health is best for:

  • People whose main focus is heart disease risk, with Lp(a) and lifetime heart-attack risk estimates in one panel.
  • People who want a one-time panel without a yearly membership.
  • People who want a video visit with a board-certified doctor and repeat testing at 3 and 9 months, through the $399 Advanced program.
  • People in New York and New Jersey who want a smaller state surcharge, $99 against Superpower's $250.

Empirical Health vs Superpower: the bottom line

Each company hands you real data. Empirical Health's $190 panel puts ApoB, Lp(a), and lifetime heart-risk estimates into one lab visit, and its $399 Advanced program adds repeat testing and a doctor visit. But its testing is built around your heart. Superpower includes a member-priced supplement marketplace; Empirical Health does not offer one.

One $349 membership lets Superpower close that loop. Superpower AI reads your wearable data and medical records alongside 150+ lab tests across two draws, and delivers a protocol plus coaching between draws. At member pricing, the marketplace holds the supplements your protocol calls for, and prescriptions are available when clinically appropriate, priced separately. Superpower says 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.

Frequently asked questions

References

  1. Empirical Health. (2026). Don't die of heart disease. Empirical Health.
  2. Empirical Health. (2026). On-demand heart health lab test. Empirical Health.
  3. Empirical Health. (2026). 12-Month Advanced Heart Health Program. Empirical Health.
  4. Empirical Health. (2026). Frequently asked questions. Empirical Health.
  5. Empirical Health. (2026). Find labs and blood tests near you. Empirical Health.
  6. Empirical Health. (2026). Function Health vs Empirical Health. Empirical Health.
  7. Empirical Health. (2026, February 17). Empirical Health for web: Now available on desktop. Empirical Health.
  8. Empirical Health. (2026). Which wearables do Empirical Health and Sleep support? Empirical Health Knowledge Base.
  9. Empirical Health. (2026). Where do I go for my blood draw? Empirical Health Knowledge Base.

Put your health in trusted hands

  • Harvard Medical School
  • University of Chicago Pritzker School of Medicine
  • UCLA
  • Tufts School of Medicine
Dr. Anant Vinjamoori

Dr. Anant Vinjamoori, MD

Chief Longevity Officer, Superpower

Dr. Leigh Erin Connealy

Dr. Leigh Erin Connealy, MD

Clinician & Founder of The Centre for New Medicine

Dr. Abe Malkin

Dr. Abe Malkin, MD

Founder & Medical Director of Concierge MD

Dr. Robert Lufkin

Dr. Robert Lufkin, MD

Physician & UCLA Medical School Professor, NYT bestselling author

4.5 out of 5Trustpilot

Transforming 150,000+ lives and counting

Camelia, 29

Camelia, 29

“I left the appointment feeling like I was being dramatic. I wasn't being dramatic. I was being responsible.”

Doctors refused to test her fertility, so she took control of her health

Thach, 37

Thach, 37

“They told me I was overthinking my genetic risk of diabetes but when I tested with Superpower I found my A1c was really high.”

His Superpower test caught diabetes risk that two doctors missed

Carissa, 38

Carissa, 38

“I spent almost a year thinking something was wrong with me. Turns out a simple blood test could have told me in a week.”

Uncovered the hormone imbalances behind bloating and weight gain

Teva, 28 and Cole, 29

Teva, 28 and Cole, 29

“I got my boyfriend a Superpower blood test. And it opened his eyes to things that seriously needed to change.”

The gift that changed how they think and talk about health

Ron, 53

Ron, 53

“I was putting in so much effort to improve my health. But nothing was working, until I got testing that actually showed me what to focus on.”

Superpower gave him a supplement plan that saved him time and money

1 / 5
Biological age 32 — a Superpower member portraitA health system built around you — test, understand, optimize150+ biomarkers across 2 blood drawsWhat to expect with Superpower — week 1 to month 3Trusted by 64,000+ customers — member reviewsBetter than the status quo — Superpower vs the old way60% of members found something a doctor missed — member survey
Daniel OSuperpower memberDavid LSuperpower memberRachel DSuperpower memberCamelia VSuperpower member

4.6 · 64,000+ members

Superpower health membership

Find early signs of 1,000+ conditions - then act, retest, and see what changed.

$199

$349

/year*

Limited time: $150 off

150+ biomarkers annually across baseline + retest

Personalized plan that turns results into action

Superpower AI and on-demand care team

Results in 10 days or less

At-home or 2,000+ labs nationwide**

Yearly membership$0.55 / dayHSA/FSA eligible

*Pricing may vary for members in New York and New Jersey

**At-home labs for an additional cost

What we test

TestosteroneFree T4Vitamin DApoBHbA1cThyroid (TSH)hs-CRPFerritinCortisolFasting insulin

60%

found something a doctor missed

93%

rated it more useful than their checkup

77%

found something new in their results

Superpower member survey, 90 days post action plan (n=143).

How does the Superpower membership work?

We test 150+ biomarkers annually across two blood draws. Your baseline test paints a comprehensive picture of your health, and your dashboard shows what’s working, what needs attention, and what to do next. Superpower AI and your care team help you take action across lifestyle, supplements, and treatments. Then we retest to track your progress and continue refining your plan.

Can I cancel anytime?

Yes. You can cancel anytime, no fees. Your membership stays active through the end of your paid year.

How often should I test?

Your membership includes two blood tests per year: one to establish your baseline, and one to see whether your plan improved biomarkers that were out of range or not yet optimized. You can add other diagnostics anytime through the app or with help from your care team.

When will I get my results?

Book your draw at any of 2,000+ partner labs or at-home. Results are typically ready in about a week and land in the Superpower app.

What the 100+ panel measures

All 101 markers in your annual baseline draw, organized by system. Nothing here is an upsell.

Heart & Vascular Health

26

  • Apolipoprotein B
  • Atherogenic Coefficient
  • Atherogenic Index of Plasma
  • Castelli Risk Index I
  • Castelli Risk Index II
  • HDL Cholesterol
  • LDL Cholesterol
  • LDL/HDL Ratio
  • Cholesterol, Total
  • Non-HDL Cholesterol
  • Cholesterol/HDL Ratio
  • Carbon Dioxide, Total
  • High-sensitivity CRP
  • hsCRP-to-Albumin Ratio (CAR)
  • GGT-to-HDL Cholesterol Ratio
  • LDL-C to Apolipoprotein B Ratio (LDL-C/ApoB)
  • LDL Cholesterol / Total Cholesterol (Mass Ratio)
  • Monocyte-to-HDL Ratio (MHR)
  • Neutrophil-to-HDL Cholesterol Ratio (NHR)
  • Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB)
  • NON-HDL Total Cholesterol Ratio
  • Triglyceride HDL Molar Ratio
  • Triglycerides
  • Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB)
  • TyG Index
  • Uric Acid

Metabolic Health

4

  • Estim. Avg Glu (eAG)
  • Eag (mmol/l)
  • Glucose
  • Hemoglobin A1c

Energy

1

  • Cortisol

Liver Health

15

  • Albumin/Globulin Ratio
  • Albumin
  • Alkaline Phosphatase (ALP)
  • Alanine Aminotransferase (ALT)
  • Aspartate Aminotransferase (AST)
  • Bilirubin Direct
  • Bilirubin Indirect
  • Bilirubin, Total
  • Bilirubin-to-Albumin Ratio
  • Ferritin
  • Ferritin-to-Albumin Ratio
  • y-Glutamyl Transferase (GGT)
  • Globulin, Total
  • Indirect-to-Direct Bilirubin Ratio
  • Protein, Total

Kidney

11

  • Calcium
  • Chloride
  • Corrected Calcium (Albumin-adjusted)
  • Creatinine
  • Estimated Glomerular Filtration Rate (eGFR)
  • Potassium
  • Sodium
  • BUN/Creatinine Ratio
  • Blood Urea Nitrogen (BUN)
  • Urea-to-Creatinine Ratio
  • Uric Acid-to-HDL Cholesterol Ratio (UHR)

Sex Hormones

7

  • DHEA-Sulfate (DHEA-S)
  • Free Androgen Index
  • Sex Hormone Binding Globulin (SHBG)
  • Free Testosterone
  • Testosterone, Bioavailable
  • Testosterone, Total
  • Testosterone-to-Estradiol Ratio (T/E₂)

Thyroid Health

4

  • Free Thyroxine Index
  • T3 Uptake
  • T4 (thyroxine) Total
  • Thyroid-Stimulating Hormone (TSH)

Nutrients

13

  • Vitamin D
  • Red Cell Dist Width (RDW)
  • Hematocrit
  • Hemoglobin
  • Total Iron Binding Capacity (TIBC)
  • Iron
  • Iron Saturation
  • Mean Cell Hemoglobin (MCH)
  • Mean Corpuscular Hemoglobin Concentration (MCHC)
  • Mean Cell Volume (MCV)
  • Platelet-to-WBC Ratio (PWR)
  • Red Blood Cells
  • RDW MCV Ratio

Immune System

12

  • Basophils
  • Baso (Absolute)
  • Eosinophils
  • Eos (Absolute)
  • Lymphocytes
  • Lymphs (Absolute)
  • Monocytes
  • Monocytes (Absolute)
  • Neutrophils
  • Neutrophils (Absolute)
  • Mean Platelet Volume
  • Platelet Count

Inflammation

8

  • Lymphocyte-to-Monocyte Ratio (LMR)
  • Monocyte-to-Lymphocyte Ratio (MLR)
  • Neutrophil-to-Lymphocyte-Platelet Ratio (NLPR)
  • Neutrophil-to-Lymphocyte Ratio (NLR)
  • Platelet-to-Lymphocyte Ratio (PLR)
  • Systemic Immune-Inflammation Index
  • Systemic Inflammation Response Index (SIRI)
  • White Blood Cells
Get my health baseline

The full list of 100+ markers and 8 specialty add-ons available at superpower.com/biomarkers.