Key takeaway:
What is Superpower, and what is SiPhox Health?
Superpower and SiPhox Health are both biomarker testing companies. A biomarker testing company offers blood-based testing on a periodic basis. Biomarkers are measurable signals in your blood, things like cholesterol, blood sugar, and hormones.
Some platforms stop at data and a report. Others turn results into a plan you can act on. Two questions separate them: how much do they measure, and what do they help you do next?
Superpower and SiPhox answer those differently. One is a full membership with care built in; the other is a convenient self-serve tracker whose cost scales with how often you test.
What does Superpower include?
Superpower includes a full annual membership, from an initial venous draw through on-demand care-team access. Superpower follows a simple path:
- Join for $349 a year.
- Give your initial venous blood draw at a lab, or at home for an added fee.
- Receive ~90 health metrics in your dashboard.
- Get a personalized action plan.
- Give a built-in follow-up draw later, retesting ~60 biomarkers.
- Message your care team on demand.
Both draws happen at any of 2,000+ partner locations across 40+ states, or at home for an added fee. Results arrive in your dashboard 5 to 10 business days after each one.
Among those results is a biological-age score, included in every membership. It's a single number for your whole body, so an optional OrganAge add-on breaks it into nine organ-level scores, across systems like metabolism, inflammation, liver, and kidney health, showing you which ones are pulling the total up or down.
You can shop a supplement marketplace with member-exclusive pricing, and prescriptions are available through the marketplace, when clinically appropriate, priced separately.
What does SiPhox Health include?
SiPhox Health includes an at-home kit with needle-free capillary collection, processed through a CLIA-certified lab. SiPhox is built for convenience. You order a kit, collect a sample at home with its needle-free EasyDraw upper-arm device, then mail it to a CLIA-certified lab. There's no vein draw and no lab visit, which is its genuine edge.
Results come back in 7 to 10 days, paired with AI-generated insights and supplement recommendations. Its broadest tier, Ultimate 360, runs 59 biomarkers, against 29 on Longevity Essentials, and you can retest monthly, quarterly, or every six months. Human coaching is an optional paid add-on, not an included care team.
What biomarkers do the Superpower and SiPhox Health memberships measure in 2026?
Superpower reports 150+ tests across two draws — ~90 from an initial venous draw, plus a built-in follow-up retesting ~60 of those markers — while SiPhox Health measures 29 biomarkers on Longevity Essentials up to 59 on Ultimate 360 per at-home capillary kit. The two count on different bases. Superpower's headline is a two-draw total; SiPhox's is the size of a single panel. In both, repeat testing re-runs markers already on the panel rather than adding new ones.
| Superpower | SiPhox Health | |
|---|---|---|
| Counted from | Initial venous draw of ~90 biomarkers, plus a built-in follow-up that retests ~60 of those same markers | One at-home capillary kit: 29 biomarkers on Longevity Essentials up to 59 on Ultimate 360, with retests repeating that same panel |
| Accuracy vs. venous | Venous draw is the reference standard | Correlates well with venous methods for markers like HbA1c, glucose, and CRP, but research has found weaker correlation for some lipids |
*Superpower's 150+ combines direct lab measurements with calculated metrics like LMR, MLR, and Ferritin:Albumin, spanning an initial draw and a built-in follow-up retest of the same markers. Both run through CLIA-certified labs.
What support and next steps do Superpower and SiPhox Health offer?
This is where the two diverge most. Superpower includes on-demand access to a care team you can message about your results, plus prescriptions are available through the marketplace, when clinically appropriate, priced separately, including TRT. A curated supplement marketplace offers member-exclusive pricing.
SiPhox works differently. It gives you AI-generated insights and supplement recommendations, with human coaching as a paid add-on. There's no included clinician care team, and no prescription access.
SiPhox hands you data and suggestions; Superpower keeps testing and action under one roof. 93% of members rated their Superpower Health Action Plan as more useful or even life-changing compared to their yearly checkup.
What are the official 2026 membership prices for Superpower and SiPhox Health?
SiPhox can cost less at entry, with membership starting at $125 per testing period for one of four core panels.
- Superpower: $349/year, HSA/FSA eligible.
- SiPhox Health: membership starts at $125 per testing period; pricing scales with cadence and panel choice — the broader Ultimate 360 panel adds $125, and a GLP monitoring panel adds $75; also HSA/FSA eligible.
Who is Superpower best for, and who is SiPhox Health best for?
Superpower is best for:
- People who want a full venous baseline of ~90 health metrics, 150+ tests across two draws.
- People who want a protocol and on-demand care, not just data.
- People who want supplement and prescription access in one place.
- People who want their biological age broken out organ by organ.
SiPhox Health is best for:
- Budget self-trackers who want frequent at-home panels.
- People who want needle-free home collection with no lab visit.
- People who mainly want data and trend tracking over guidance.
Test 150+ biomarkers
Two draws included. Get a full picture of your health and the action plan you need to improve it.
Test 150+ biomarkers
Two draws included. Get a full picture of your health and the action plan you need to improve it.
The final word: does Superpower or SiPhox Health fit you?
SiPhox Health wins on entry convenience: needle-free at-home collection with flexible retesting, from $125 per testing period. If low-friction data tracking is all you want, it delivers.
But it stops there, at data and recommendations, and the needle-free format comes with a trade-off. SiPhox's broadest panel runs 59 biomarkers, against ~90 on Superpower's initial venous draw, and capillary samples correlate less well with venous methods for some lipids. Convenience answers what your numbers are; turning that into a next step is left to you.
Superpower: a fuller panel and built-in care vs. SiPhox's needle-free convenience
SiPhox Health's needle-free convenience leaves the next step up to you: track your numbers over time, then decide on your own what to do about a marker that moved or an insight its AI flagged. Superpower folds testing and action into one $349/year membership: ~90 health metrics from an initial venous draw, plus a built-in follow-up retesting ~60 of those same markers, 150+ tests across the two. Each round lands with a personalized action plan, and on-demand care-team messaging carries you between them. SiPhox's $125-per-testing-period model gives you the numbers and the recommendations, then leaves the deciding to you.
Starting with a full picture, not just a single data point, is the better place to begin a health journey. Start your Superpower blood test and see where your numbers actually stand.
Other companies you should compare
Frequently asked questions
References
- SiPhox Health. (2026). How much does SiPhox Health cost? SiPhox Health.
- SiPhox Health. (2026). Programs and pricing. SiPhox Health.
- SiPhox Health. (2026). How it works. SiPhox Health.
- SiPhox Health. (2026). At-home blood testing and personalized action plan. SiPhox Health.
- OptimizeBiomarkers. (2026). SiPhox Health review 2026. OptimizeBiomarkers.
- Lacher, D. A., et al. (2013). Comparison of dried blood spot to venous methods for hemoglobin A1c, glucose, total cholesterol, HDL cholesterol, and C-reactive protein. PubMed.
- Crimmins, E., Kim, J. K., McCreath, H., & Faul, J. (2014). Validation of blood-based assays using dried blood spots for use in large population studies. Biodemography and Social Biology. PubMed.
