Phosphatidyl Choline

Support your brain health and cellular function with Phosphatidyl Choline as part of your daily wellness routine.

December 5, 2025
Author
Superpower Science Team
Reviewed by
Julija Rabcuka
PhD Candidate at Oxford University
Creative
Jarvis Wang

Key Facts

  • Phosphatidyl choline is a phospholipid that forms the structural backbone of cell membranes throughout your body
  • Supports liver cell renewal and fat digestion by maintaining healthy hepatocyte membranes
  • Works as a building block for acetylcholine, a neurotransmitter involved in cognitive function and memory
  • Available in gel cap form for consistent absorption and ease of use

Ingredients

Phosphatide complex (phosphatidylcholine) 420 mg, gelatin (bovine), purified water, and vegetable-source glycerin.

Why We Chose This

Your liver cells are constantly replacing their outer membranes, and phosphatidyl choline is the primary material they use for that job. Without adequate phosphatidyl choline, this renewal process slows down, which can compromise liver function and your body's ability to process dietary fats efficiently. Thorne's formulation delivers a clinically relevant dose in a bioavailable gel cap form, ensuring your hepatocytes get the structural support they need to keep working optimally. This aligns with a longevity-focused approach to cellular health, where maintaining membrane integrity is foundational to sustained organ function.

Frequently Asked Questions About Phosphatidyl Choline

What is the supporting research for the benefits of phosphatidyl choline?
  • A PC preparation is associated with improved remission rates in ulcerative colitis. (ulcerative colitis trial)
  • Oral phosphatidylcholine may restore neuronal plasticity in neural stem cells. (neural stem cell study)
  • Phosphatidylcholine supplementation may attenuate non-alcoholic fatty liver disease onset. (NAFLD model)
How do I take phosphatidyl choline?

Take 1-2 capsules daily with a meal to support liver health and cellular function.

Start with the lower dose for 6-12 weeks, then adjust based on your individual needs.

Can I take phosphatidyl choline with other supplements or medications?

Phosphatidyl choline has no known interactions with most supplements or medications. However, it may increase acetylcholine levels, so check with your doctor if you're taking glaucoma or Alzheimer's medications.

Who might benefit from taking phosphatidyl choline?

People looking to support liver health and fat digestion, as well as those interested in cognitive function and cellular membrane integrity, may find phosphatidyl choline beneficial. Those with liver stress from toxins or alcohol, and pregnant individuals seeking fetal brain development support, represent key populations exploring this supplement.

How long does it typically take to notice effects of phosphatidyl choline?

Most people notice gradual improvements over 6 to 12 weeks of consistent use, though some experience benefits within the first few weeks. Individual timelines vary based on your baseline health status and how your body processes the supplement.