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Sex Hormones

Cardio IQ Insulin Biomarker Test

Measure your Cardio IQ Insulin to detect hidden insulin resistance before glucose or A1c rise, gauge cardiometabolic and fertility risk, and guide targeted lifestyle changes.

With Superpower, you have access to a comprehensive range of biomarker tests.

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Sample type:
Blood
HSA/FSA:
Accepted
Collection method:
In-person at the lab, or at-home

Key Benefits

  • Understand your insulin level to uncover hidden insulin resistance early.
  • Spot early metabolic imbalance before glucose or HbA1c show prediabetes.
  • Guide targeted nutrition, activity, and weight strategies to improve insulin sensitivity.
  • Flag cardiometabolic risk tied to high insulin, including unhealthy cholesterol patterns.
  • Protect fertility by identifying insulin resistance common in PCOS and ovulatory issues.
  • Support pregnancy planning by assessing risk for gestational diabetes.
  • Track progress by trending insulin alongside glucose to gauge therapy response.
  • Interpret results best when fasting with glucose, HbA1c, and HOMA-IR for insulin resistance.

What is Cardio IQ Insulin?

Cardio IQ Insulin is a blood test that measures the amount of insulin in your bloodstream. Insulin is a short protein hormone (peptide) made by the beta cells of the pancreas (islets of Langerhans). It is built from a precursor (proinsulin) and released when blood sugar rises after a meal, aided by signals from the gut (incretins).

Insulin’s central job is to move fuel into cells and coordinate storage. It tells muscle and fat to take up glucose, helps the liver and muscle store it as glycogen, suppresses the liver’s output of new glucose, and shifts the body toward building and storing (lipogenesis, protein synthesis) while slowing fat breakdown (antilipolysis). A blood insulin value reflects how strongly the pancreas is signaling to control blood sugar and manage energy use. Because insulin shapes many metabolic pathways, its level also speaks to the body’s broader metabolic state (glucose homeostasis, hepatic glucose production, lipid handling) that ties everyday energy balance to cardiometabolic health.

Why is Cardio IQ Insulin important?

Insulin is the body’s fuel-partitioning hormone, directing glucose into cells, storing energy in fat and liver, and signaling blood vessels, kidneys, ovaries/testes, and the brain. Cardio IQ Insulin measures fasting insulin to show how hard the pancreas must work to keep glucose normal—an early window into insulin sensitivity and cardiometabolic risk, often changing years before glucose or A1c.

In general, fasting insulin is reported within a broad reference range; for most adults, metabolic “sweet spot” tends to sit toward the low-normal end, reflecting efficient insulin signaling without overproduction.

When insulin is low and glucose is normal, it usually reflects high insulin sensitivity or a prolonged fasting state—cells take up glucose readily, energy is steady, and fat storage signals are quiet. When insulin is very low with high glucose, it suggests inadequate production (autoimmune diabetes, pancreatic injury), with thirst, frequent urination, weight loss, and possible ketones. In children and teens, very low insulin with hyperglycemia warrants urgent evaluation. During pregnancy, unusually low insulin with rising glucose is atypical and suggests beta-cell strain.

Higher fasting insulin indicates insulin resistance: the pancreas is compensating. This drives liver fat formation, higher triglycerides, lower HDL, higher blood pressure, endothelial dysfunction, and inflammation. People may notice post-meal sleepiness, cravings, abdominal weight gain, or acanthosis nigricans. In women it can underlie polycystic ovary syndrome; in men, low testosterone is more common. Puberty raises insulin needs; persistently high values signal future diabetes, fatty liver, and cardiovascular disease. In pregnancy, markedly elevated insulin with rising glucose aligns with gestational diabetes physiology.

Big picture: fasting insulin integrates with glucose, A1c, C‑peptide, lipids, liver enzymes, and blood pressure to map metabolic health. Keeping insulin demand low-normal signals resilient mitochondria, healthier vessels, and reduced long-term cardiometabolic risk.

What Insights Will I Get?

Cardio IQ Insulin measures the amount of insulin circulating in your blood, usually in the fasting state. It reflects how much work your pancreas (beta-cells) must do to keep glucose stable and is a window into insulin sensitivity. Because insulin coordinates energy use, lipid handling, vascular tone, inflammation, reproductive hormone balance, and brain signaling, fasting insulin is a core marker of cardiometabolic health and future cardiovascular risk.

Low values usually reflect efficient insulin sensitivity or prolonged fasting, meaning the body needs little insulin to keep glucose in range. In children and lean, active adults, lower-normal levels are common. If insulin is low despite high glucose, it suggests impaired beta‑cell output (insulin deficiency), as in autoimmune diabetes or pancreatic disease. In pregnancy, unusually low insulin with hyperglycemia is concerning.

Being in range suggests balanced insulin secretion and clearance, steady glucose delivery to tissues, and lower cardiometabolic stress. Many experts view the lower end of the fasting reference interval as a marker of good insulin sensitivity when glucose is normal and there are no hypoglycemic symptoms.

High values usually reflect insulin resistance—the tissues respond poorly, so the pancreas compensates by secreting more. This hyperinsulinemia drives atherogenic lipids, endothelial dysfunction, higher blood pressure, visceral fat storage, fatty liver, and pro‑inflammatory signaling. In women it often accompanies ovulatory dysfunction or polycystic ovary syndrome. Levels tend to run higher in puberty and with aging. Persistently high insulin, even with normal glucose, indicates elevated cardiometabolic risk.

Notes: Fasting status, recent meals, acute stress/illness, and vigorous exercise influence levels. Pregnancy and puberty raise insulin needs. Kidney or liver impairment can elevate insulin by reducing clearance. Corticosteroids, some antipsychotics, insulin secretagogues, and incretin therapies alter results. Assay methods vary; interpret against the lab’s reference interval.

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Superpower Chief Longevity Officer, Harvard MD & MBA

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Clinician & Founder of The Centre for New Medicine

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Founder & Medical Director of Concierge MD

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UCLA Medical Professor, NYT Bestselling Author

membership

$17

/month
Billed annually at $199
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Your membership includes one comprehensive blood draw each year, covering 100+ biomarkers in a single collection
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Frequently Asked Questions

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How it works
What should I expect during a blood draw?
  • A trained phlebotomist will guide you through the process.
  • A tourniquet is placed on your arm, the site is cleaned, and a small needle is used to collect blood into one or more tubes.
  • Results are usually ready in about a week.
  • Most people feel only a quick pinch.
  • The needle is removed, gentle pressure is applied, and a bandage is placed.
How do I prepare for a blood draw?
  • Drink plenty of water beforehand — hydration makes veins easier to find.
  • Wear loose sleeves so your arm is easy to access.
  • Follow any fasting instructions you’ve been given.
  • Let us know if you’re on medications, have fainted before, or have needle anxiety.
What should I do after my blood draw?
  • Press gently on the site for a few minutes.
  • Keep the bandage on for 4-6 hours.
  • Skip heavy lifting or strenuous exercise for the rest of the day.
  • Drink extra water to rehydrate.
  • Monitor the site for redness, swelling, or pain.
How do I book a blood draw with Superpower?

Your membership includes:

  • An annual full body test and report across 100+ biomarkers
  • A personalized action plan to optimize your biomarkers and reach your health goals
  • A dashboard to centralize your health data and track changes across a lifetime
  • Access to a health concierge for questions on your plan and help scheduling
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Many concierge clinics charge $10k – $100k for their services, we’ve built technology to make the world’s best healthcare as accessible as possible via an all-in-one membership.

Where can I take my blood test?

Superpower is currently available in the following US states:

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Our testing
Does Superpower replace my primary care provider?

Superpower specializes in prevention-based testing and treatments and is not intended for emergency or immediate health issues.

While you will have a Superpower care team, your annual membership is designed to complement a primary care doctor if you have one, not replace them.

We are happy to help you share any test results with an outside provider to ensure you receive well-rounded medical care.

How fast are blood test results and how do I read them?

Your annual lab test panel takes about 10 days to process. We will text you as soon as they become available in your dashboard. Other types of tests may have different testing windows. The Superpower concierge is your own health assistant who helps answer your questions on your results, ensure smooth scheduling, coordination of any office-based tests, specialist referrals as needed, and navigating you to interface with your care team.

Does Superpower accept health insurance?

Superpower membership and products are all eligible for HSA/FSA funding.

We see Superpower like a gym membership for those committed to prevention and performance. Superpower is a bridge between wellness and healthcare. Health insurance traditionally focuses on reactive care whereas, at Superpower, we believe it’s never too early to start looking out for your long-term health.

What if I want more than 1 blood test per year?

Absolutely — you're not limited to just one. Your membership includes one comprehensive 100+ biomarker blood test each year, but if you'd like to track your progress more closely, you can add extra tests at any time. Each additional full-panel test costs $179. You can order as many as you'd like throughout the year.

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Frequently Asked Questions about Cardio IQ Insulin

What is the Cardio IQ Insulin test and what does it measure?

The Cardio IQ Insulin test is a blood test that measures the amount of insulin circulating in your bloodstream, typically in a fasting state. Insulin is a hormone produced by the pancreas that helps regulate blood sugar by signaling cells to absorb glucose. This test provides insight into how hard your pancreas must work to keep glucose levels stable and serves as an early indicator of insulin sensitivity or resistance. By assessing fasting insulin, the Cardio IQ Insulin test helps uncover hidden metabolic imbalances, guides targeted lifestyle interventions, and flags cardiometabolic risks before changes in glucose or HbA1c appear.

How does the Cardio IQ Insulin test help detect early insulin resistance?

The Cardio IQ Insulin test can reveal elevated insulin levels even when glucose and HbA1c are still normal, making it a valuable tool for detecting early insulin resistance. Insulin resistance occurs when the body’s tissues respond poorly to insulin, causing the pancreas to produce more to maintain normal blood sugar. Early detection allows for timely interventions in diet, exercise, and weight management to improve insulin sensitivity and prevent progression to prediabetes, type 2 diabetes, and related cardiometabolic conditions.

Why is fasting required for the Cardio IQ Insulin test?

Fasting is required for the Cardio IQ Insulin test because recent food intake can significantly raise insulin levels, making it difficult to interpret results accurately. Fasting ensures that the measured insulin reflects your baseline metabolic state, not a temporary response to a meal. This allows for a more reliable assessment of insulin sensitivity, pancreatic function, and overall metabolic health. For best results, the test is often paired with fasting glucose, HbA1c, and HOMA-IR calculations.

What are the benefits of knowing your fasting insulin level?

Knowing your fasting insulin level offers several benefits: it helps identify early insulin resistance, guides personalized nutrition and exercise strategies, flags increased cardiometabolic risk, and supports fertility and pregnancy planning. Tracking fasting insulin over time can also monitor the effectiveness of lifestyle or medical interventions. Lower-normal fasting insulin typically indicates efficient insulin sensitivity, while higher levels suggest the pancreas is compensating for resistance, increasing the risk for diabetes, fatty liver, and cardiovascular disease.

How does high fasting insulin relate to cardiometabolic risk?

High fasting insulin, or hyperinsulinemia, is a marker of insulin resistance and is closely linked to increased cardiometabolic risk. Elevated insulin drives the formation of liver fat, raises triglycerides, lowers HDL cholesterol, increases blood pressure, and promotes inflammation and endothelial dysfunction. Over time, these changes contribute to the development of atherosclerosis, fatty liver disease, and type 2 diabetes. Monitoring fasting insulin helps identify individuals at risk before overt glucose abnormalities develop.

Can the Cardio IQ Insulin test help with fertility and pregnancy planning?

Yes, the Cardio IQ Insulin test is valuable for fertility and pregnancy planning. Insulin resistance is common in women with polycystic ovary syndrome (PCOS) and can cause ovulatory dysfunction, impacting fertility. During pregnancy, elevated insulin levels with rising glucose may indicate gestational diabetes risk. Early identification of insulin resistance allows for targeted interventions to improve reproductive health and reduce complications during pregnancy.

What do low fasting insulin levels indicate?

Low fasting insulin levels, when glucose is normal, usually reflect high insulin sensitivity or a prolonged fasting state, meaning the body efficiently uses insulin to regulate blood sugar. In children, lean, and active adults, lower-normal insulin is common. However, if insulin is low despite high glucose, it may indicate impaired pancreatic function, such as in autoimmune diabetes or pancreatic injury. In pregnancy, unusually low insulin with hyperglycemia is concerning and warrants further evaluation.

How should Cardio IQ Insulin results be interpreted alongside other tests?

Cardio IQ Insulin results are best interpreted in conjunction with fasting glucose, HbA1c, and HOMA-IR to assess insulin resistance. Integrating these markers with C-peptide, lipid panels, liver enzymes, and blood pressure provides a comprehensive view of metabolic health. This approach helps identify early metabolic imbalances, guides therapy, and tracks progress over time. Always compare results to the lab’s reference interval and consider factors like fasting status, recent illness, or medications.

What factors can affect Cardio IQ Insulin test results?

Several factors can influence Cardio IQ Insulin test results, including recent meals, acute stress, illness, vigorous exercise, pregnancy, and puberty. Certain medications—such as corticosteroids, antipsychotics, insulin secretagogues, and incretin therapies—can also alter insulin levels. Kidney or liver impairment may elevate insulin by reducing its clearance. It’s important to follow fasting instructions and inform your healthcare provider about any medications or health conditions before testing.

What are common misconceptions about fasting insulin and insulin resistance?

A common misconception is that normal glucose or HbA1c levels always mean healthy insulin function. In reality, insulin resistance can develop years before glucose or HbA1c become abnormal, making fasting insulin a more sensitive early marker. Another misconception is that only overweight individuals develop insulin resistance; in fact, lean people can also be affected, especially with genetic predisposition or certain lifestyle factors. Understanding fasting insulin helps uncover hidden risks and supports proactive health management.

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