Superpower vs Empirical Health

Superpower vs Empirical Health, compared

Superpower and Empirical Health both start with an annual biomarker panel at a similar price. Superpower is $199 a year and includes 100+ health metrics, a personalized action plan, on-demand care-team access, and a supplement and prescription marketplace.

Empirical Health is about $190 for a cardiovascular-focused panel, plus an ongoing physician-led primary-care relationship (insurance-billable visits, billed separately) with Apple Watch monitoring.

What these services actually are

A biomarker testing company offers blood-based testing on a membership basis, measuring your biomarkers at set intervals. Biomarkers are measurable signals in your blood: things like cholesterol, blood sugar, and inflammation.

Two questions separate these services: how much do they measure, and what do they help you do next? It's worth noting the two answer differently.

Empirical extends into ongoing primary care. Superpower extends into a protocol plus a supplement and prescription marketplace.

What Superpower includes

Superpower follows a simple path:

1. Join for $199 a year.
2. Give one blood draw at a lab, or at home for an added fee.
3. Receive 100+ health metrics in your dashboard.
4. Get a personalized action plan.
5. Message your care team on demand.

Testing reaches 2,000+ partner locations across 40+ states. Results arrive in 5-10 business days. You can shop a supplement marketplace with member-exclusive pricing, and prescription and peptide access is available in the marketplace (medications priced separately).

A biological-age score is built into every Superpower membership, with an optional OrganAge add-on for a deeper organ-level view. Gut microbiome testing is also available as an add-on.

What Empirical Health includes

Empirical Health is a physician-led primary-care practice, not just a testing company. Its single in-lab draw covers a cardiovascular-focused panel, and an in-house physician reviews an AI-generated action plan.

From there, you get insurance-billable video visits and doctor messaging, billed separately from the panel. Continuous Apple Watch, Fitbit, and Samsung data (ECG, HRV, sleep) feeds those care plans.

Results return in about 3-7 business days. There's no supplement marketplace, no gut testing, and prescriptions come through the care relationship.

What you actually measure

This is the most scrutinized comparison point, so precision matters. Both market "100+." The two count on different bases, though.

• Headline count — Superpower: 100+ health metrics*; Empirical Health: 100+ biomarkers (~85 measured)**
• Counted from — Superpower: One blood draw; Empirical Health: One blood draw
• Focus — Superpower: Whole-body; Empirical Health: Cardiovascular / metabolic

*Superpower's 100+ combines direct lab measurements with calculated ratios like LMR, MLR, and Ferritin:Albumin.
**Third-party breakdowns list ~85 measured markers, skewed to heart and metabolic panels (ApoB, Lp(a), hs-CRP, lipids, HbA1c). Empirical's depth on cardiovascular markers is real; Superpower's strength is breadth across more body systems.

Support and next steps

This is where the two diverge most. Superpower includes on-demand access to a care team you can message about your results, plus a curated supplement marketplace and prescription access (GLP-1, TRT, and clinically appropriate peptides), all in one membership.

Empirical works differently. Its strength is an ongoing, insurance-billable physician relationship: video visits, referrals, and prescriptions through the practice.

Superpower complements your primary-care doctor rather than replacing one. The trade-off is real: a doctor relationship versus a testing-to-action loop under one roof.

Value for money

Superpower costs $199 a year. Empirical Health's panel is about $190, so on testing alone the prices are close. But the panel is only the entry point.

Empirical's physician visits are an additional cost on top of the panel, though they bill to insurance, so the all-in cost depends on how much you use the care relationship. Superpower's $199 already bundles more than data: a protocol, a supplement marketplace, and prescription access, with no add-on.

Both are HSA/FSA eligible, so pre-tax dollars can cover either. The honest read: panel prices are comparable, so the choice comes down to what's bundled around them, and what you pay on top.

Best fit for you

Superpower is best for:

• People who want broad whole-body testing, not just heart markers.
• People who want a protocol plus supplements and Rx at member-exclusive pricing in one membership.
• People who want gut-microbiome or OrganAge add-ons.
• People optimizing health alongside their existing doctor.

Empirical Health is best for:

• People who want an ongoing, insurance-billable physician-led primary-care relationship.
• People whose main focus is cardiovascular risk.
• People who want continuous Apple Watch monitoring reviewed by a doctor.

The final word

At a similar panel price, both give a serious baseline. Empirical Health is a genuine physician-led primary-care relationship with Apple Watch monitoring, a real strength if you want an ongoing doctor.

But two things separate them. Empirical's panel is concentrated in cardiovascular and metabolic health, while Superpower spans 100+ whole-body metrics, so you see heart and metabolism in context with everything else. And Empirical's physician visits are billed separately on top of the panel, where Superpower bundles a protocol, on-demand care, and a supplement and prescription marketplace into one flat $199 a year.

A good doctor relationship still needs a complete picture to work from. Superpower hands you one on day one, with no per-visit meter running, and in its member data 60% spotted something a previous doctor had missed or overlooked. Breadth first, then the plan to act on it.