Progesterone Add-on

The Progesterone Add-on checks whether ovulation occurred this cycle and screens for a pattern of excess adrenal androgen production. Add it to your Superpower order and review your results with your care team or share them with your provider.

About the Progesterone Add-on

This add-on measures progesterone and 17-hydroxyprogesterone (17-OHP), two markers that clarify what's happening in the second half of your cycle and in your adrenal hormone production.

Progesterone rises after ovulation, so measuring it in the luteal phase confirms whether ovulation occurred that cycle. 17-OHP is an adrenal hormone precursor that can signal excess adrenal androgen production when elevated. Pair this add-on with your Superpower baseline for a fuller picture of your reproductive and adrenal hormone status.

This panel screens for hormonal patterns associated with common conditions. It does not diagnose any condition, and results should be interpreted by a qualified healthcare provider.

What's tested and why it matters

Progesterone

Progesterone confirms that ovulation occurred when measured in the luteal phase, and low luteal-phase progesterone may indicate anovulatory cycles or luteal phase insufficiency.

17-Hydroxyprogesterone (17-OHP)

An adrenal hormone precursor. Elevated 17-OHP may indicate excess adrenal androgen production, a pattern associated with late-onset congenital adrenal hyperplasia and, in some cases, with PCOS-like presentations. It is rarely included in standard hormone panels.

Reference ranges vary by lab, cycle phase, and individual. Your provider will interpret your results in the context of your timing, symptoms, and history.

Who benefits from testing

• Women with irregular, skipped, or unpredictable menstrual cycles who want to confirm whether ovulation occurred that month.
• Women with fertility concerns who want to confirm ovulation as a starting point for understanding their cycle.
• Women investigating suspected PCOS or wanting hormonal context for an existing PCOS diagnosis, since elevated 17-OHP can reflect a PCOS-like pattern of adrenal androgen production.
• Anyone whose provider is evaluating for late-onset congenital adrenal hyperplasia, a condition associated with elevated 17-OHP.
• Women who want a luteal-phase hormone baseline before starting, stopping, or changing a hormonal contraceptive or HRT regimen.

What your results reveal

Your results give you a read on two connected but distinct signals: whether ovulation occurred this cycle, and whether your adrenal hormone production shows a pattern associated with excess androgen output.

Low luteal-phase progesterone may indicate that ovulation did not occur that cycle, which is useful context if you're tracking fertility or investigating irregular cycles. Elevated 17-OHP may indicate excess adrenal androgen production, a pattern associated with late-onset congenital adrenal hyperplasia and, in some cases, with PCOS-like presentations. Your Superpower care team can walk you through what your results mean and flag what's worth a provider conversation.

How it works

1. Add the Progesterone Add-on to your Superpower order.
2. Schedule a blood draw at a local clinic, or book an optional at-home visit from a trained phlebotomist (+$119).
3. Your sample is processed in a CLIA-certified lab, and your results are delivered to your dashboard, typically within 10 days.
4. Review your results with your Superpower care team, or share them with your provider.

Frequently asked questions

This panel is for informational and screening purposes only. It does not constitute medical advice and does not diagnose PCOS, congenital adrenal hyperplasia, or any other medical condition. Reproductive and adrenal hormone levels vary significantly by cycle phase, age, and individual factors. Always consult a qualified healthcare provider to interpret your results in the context of your complete health history.