Hundred Health vs SiPhox Health

What is Hundred Health, and what is SiPhox Health?

Hundred Health bills itself as a platform where everyone has a health strategy. Lab results, medical records, and wearable data go in, and a 100-day protocol comes out.

SiPhox Health leads with "At-Home Health Testing. Fast. Painless." Members collect a sample from the upper arm at home, send it off the same day, and get a report with an action plan.

Both pair testing with a plan, and both are HSA/FSA eligible. Where they split is the draw itself: a venous draw once a year at Hundred, and a self-collected kit at SiPhox on the schedule you choose.

What does Hundred Health include?

Hundred's membership pays for a single annual panel, 100+ lab tests in all, together with imported records, synced wearables, a biological age score, and the clinician-built protocol.

Hundred describes three steps:

1. We build your complete health record — Blood is drawn at a partner lab or at home, and past records, labs, and imaging are gathered alongside your devices.
2. Your health results, finally explained — Labs and wearable data are read as one picture, compared with peers, and explained with physician-led insights.
3. Get your 100-day action plan — A clinician-built protocol covers nutrition, supplements, exercise, and lifestyle.

Its FAQ says members do not currently work with a physician directly inside the app. Clinicians shape the protocol and the AI behind it instead.

Join 150,000+ others building better health

Get the science behind better health, every week.

SubscribeSigning up...

By clicking “Subscribe” you agree to our Terms of Service and Privacy Policy.

Thanks for signing up!

Check your inbox — your first issue is on the way. We send clinically reviewed health science, never spam.

What does SiPhox Health include?

A SiPhox membership includes the kit, a health report with an action plan, scores for BioAge and Heart & Metabolic Age, and Sai, an AI health assistant.

SiPhox publishes a four-step process:

1. Join SiPhox Health — Choose a cadence of monthly, quarterly, or every 6 months when you sign up.
2. Select your health focus — Pick a panel aimed at longevity, hormones, thyroid, or heart and metabolism.
3. Test at home, painlessly — Collect a small sample from your upper arm with the EasyDraw device, with live support on the call.
4. Get insights & optimize — Read your report, then chat with Sai about the numbers.

The membership also takes in an in-app body composition scan and unlimited uploads of outside lab reports. Members can buy one coaching credit for $50, which pays for a 30-minute video call or a written action plan.

What biomarkers do Hundred Health and SiPhox Health measure in 2026?

Hundred Health publishes 100+ lab tests for one annual draw. SiPhox Health lists 31 on Longevity Essentials, 62 on Ultimate 360 (+$125), with every panel counted per test, not per year.

Counted off each published list by the same rule, the two sit far apart. Hundred's total includes about 30 urine items, and no SiPhox panel carries urinalysis.

Hundred's list tags some markers as add-ons:

• Heart and lipids — Lipoprotein(a), ApoA1, LDL particle number, and oxidized LDL.
• Nutrients and toxins — Omega fatty acids, homocysteine, zinc, and heavy metals.
• Thyroid and stress — Thyroid antibodies, free T3, cortisol, and DHEA sulfate.

SiPhox's optional add-ons cost $45 for a complete blood count and $70 for IGF-1, or $100 for both. Its shop also sells an advanced gut health test, a 295-allergen panel, a cortisol test, and a Prenuvo whole-body MRI bundle.

What are the official 2026 membership prices for Hundred Health and SiPhox Health?

Hundred Health costs $199 a year. SiPhox Health's entry price is $99 for the first kit; every renewal after it costs $124, with $25 shipping on top.

SiPhox's annual cost depends on cadence, since a year is 2, 4, or 12 kits when testing every 6 months, quarterly, or monthly. Swapping in Ultimate 360 costs $125 more, and the FAQ confirms no insurance is accepted. Both accept HSA/FSA cards.

At Hundred, optional add-on tests can carry separate fees. Hundred adds a lab fee of up to $248 a year for members in New York and New Jersey.

How does each one collect your blood?

Hundred draws venous blood, and SiPhox has you collect a small upper-arm sample yourself.

Hundred offers in-lab and in-home phlebotomy. SiPhox's EasyDraw kit needs no needles and no lab visit, and the sample goes to a CLIA-certified lab by same-day pickup.

SiPhox kits ship within 3 days and arrive in 3 to 5 days. SiPhox says to expect results 7 to 10 days after its lab receives the sample. Hundred's first results can appear in the app inside 24 hours, with the complete panel taking roughly two weeks.

One annual panel or a health focus you choose

Hundred runs one panel, and SiPhox lets members swap panels at no extra cost.

All four core SiPhox panels come with membership, from Hormone Focus at 14 markers up to Longevity Essentials at 31, with Thyroid Focus at 21 and Heart & Metabolic at 28 between them. A member who wants thyroid markers this quarter and heart markers the next can switch.

Hundred keeps one set annual list, with the 100-day protocol built after every result arrives. Its FAQ recommends a full retest every 100 days.

Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

Book your testLoading...

Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

Book your testLoading...

Who reviews your results, and what about prescriptions and supplements?

Hundred's protocol is clinician-built, while SiPhox describes its review as expert and medically overseen. SiPhox's Sai assistant says it is not a medical doctor.

Hundred prescribes weight-loss medication through a separately billed care program from $99 a month, after a consultation, in every state but Alaska, Illinois, Mississippi, and New Jersey. SiPhox members in its Heart and Metabolic Program can reach an independent provider group through its terms of service, and SiPhox itself does not provide clinical services.

Hundred sells supplements at up to 20% off retail through its member marketplace. SiPhox gives personalized supplement recommendations and sells none in its shop.

Where are Hundred Health and SiPhox Health tests available?

SiPhox serves every state except Hawaii and New York, and it also serves Canada, where members use a finger-prick method.

Hundred Health operates only in the U.S., with 5,000+ partner labs. In-lab visits are unavailable in Hawaii, North Dakota, South Dakota, and West Virginia.

Who is Hundred Health best for, and who is SiPhox Health best for?

Hundred Health is best for:

• People who want a wide annual panel and a clinician-built protocol.
• People who want supplement discounts and prescriptions on one platform.
• People who prefer a standard blood draw at a lab or from a phlebotomist.

SiPhox Health is best for:

• People who want no needles and no lab visits.
• People who want to choose a focus and a testing cadence themselves.
• People who want to connect 300+ devices or upload outside lab reports.

The bottom line

Hundred Health is the one-panel-a-year choice, with a clinician-built plan, a members-only supplement store, and a separately priced prescription program. SiPhox Health is the home-collection choice, where members pick the panel and the testing rhythm.

Both leave pieces outside the report. SiPhox recommends supplements but sells none, and SiPhox itself provides no clinical services. Hundred bills prescriptions through a separate care program from $99 a month.

Superpower's $199 a year in most states matches Hundred's, and one draw, at a lab or at home for an added $119, covers 100+ biomarkers. Superpower AI reads those results with your wearables and records and writes a Superpower Protocol, and AI and care team support takes questions on demand. Supplements come at up to 20% off in the marketplace, beside add-on tests and scans and prescriptions available when clinically appropriate, priced separately. Superpower says 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.