Superpower vs Empirical Health

How do Empirical Health and Hundred Health compare?

One of these is a doctor's office that runs a panel, and the other is a yearly program built around reading one. Empirical Health is a licensed medical practice whose in-house physicians prescribe as part of clinical care, and it sells its comprehensive panel at $190, one time. Hundred Health is a membership marketed at $16 a month, billed annually at $199, covering 100+ lab tests analyzed once a year, a 100-day personalized plan, and its own supplement marketplace; a second tier runs $1.37 a day, or $499 a year. Hundred Health draws blood across 5,000 locations, offering both in-lab appointments and in-home phlebotomy, with a handful of states excluded from one option or the other.

Almost every other difference follows from that split. A practice can act on what a panel finds inside a single relationship, ordering the next test and writing what the finding calls for. A membership turns the panel into a protocol delivered on its own terms, with member pricing on the supplements that protocol might involve and clinician-guided therapies attached to it. The marker counts are close and the headline prices are close; the shape of what you are buying is not.

Can Empirical Health or Hundred Health end your results in a prescription?

Both can, and the difference is what the prescription is attached to. Empirical Health's physicians work inside its own medical practice, so a prescription is issued as clinical care rather than sold as a separate product.

• Empirical Health: the physician reading the panel is the physician who can also order imaging, make a referral, and write what is clinically appropriate — the whole sequence stays in one place.
• Hundred Health: the membership lists personalized prescription therapies among its features, described as clinician-guided metabolic, hormone and longevity therapies.

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Besides the panel, what do Empirical Health and Hundred Health each include in the price?

Hundred Health prices two things around the panel: a supplement marketplace and HSA/FSA eligibility. The membership includes discounts on supplements in Hundred Health's own marketplace, and the membership is HSA/FSA eligible. Empirical Health does not offer a supplement marketplace, but its plans are HSA/FSA eligible too.

Neither point is glamorous and both change the arithmetic. Paying with pre-tax dollars changes what a membership billed annually at $199 actually costs you, and a plan that recommends supplements is cheaper to follow when the supplements are discounted inside the same membership. If you expect to act on your results by changing what you take, that packaging is worth pricing out before you compare the headline numbers.

What do you get after the draw: Empirical Health's medical practice or Hundred Health's 100-day plan?

Empirical Health positions itself as proactive primary care, with in-house physicians covering diagnosis, treatment, lab orders, imaging, and specialist referrals, so the panel sits inside an ongoing clinical relationship. Hundred Health returns clinician insights and a 100-day personalized plan, with clinician review and ongoing guidance listed alongside them. After the draw, the two hand you very different things.

The fork is about how much of the next step you want structured for you, and by whom. A practice is the right shape when your results might need a diagnosis, a referral, or treatment, because the person interpreting the panel is the person who can act. A 100-day plan is the right shape when you mostly want direction: a defined stretch of habits, targets, and supplements to work through, with the next reading a year away.

What are the official 2026 membership prices for Empirical Health and Hundred Health?

Empirical Health's comprehensive panel is $190, charged once. Hundred Health's entry membership is $16 a month, billed annually at $199 — nine dollars apart over a first year — and a second tier is $1.37 a day, or $499 a year, billed annually. The two prices buy different structures.

Test 150+ biomarkers

Two blood draws a year. Get a full picture of your health and the action plan you need to improve it.

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Test 150+ biomarkers

Two blood draws a year. Get a full picture of your health and the action plan you need to improve it.

Book your testLoading...

Who is Empirical Health best for, and who is Hundred Health best for?

Empirical Health is best for:

• People who want the panel inside a licensed medical practice, where the physicians reading it can diagnose, refer, and prescribe.
• People who want one $190 comprehensive panel of 100+ high-signal biomarkers, ApoB and Lp(a) included, with no recurring fee.

Hundred Health is best for:

• People who want structure more than a primary care relationship: 100+ lab tests once a year and a 100-day plan to work through.
• People who want the year packaged, with personalized prescription therapies, described as clinician-guided metabolic, hormone and longevity care, supplement discounts, and HSA/FSA eligibility all stated up front.

The bottom line: does Empirical Health or Hundred Health fit you?

If you want a doctor attached to the numbers, Empirical Health fits. If you want a plan and a price you can budget, Hundred Health fits. Choose by what you want to happen after the results land. Empirical Health is a medical practice that runs a panel: $190 one time for 100+ high-signal biomarkers, read by in-house physicians who can diagnose, refer, and prescribe inside their own practice. Hundred Health is an annual membership: $16 a month, billed annually at $199, or $499 a year on its second tier, for 100+ lab tests analyzed once a year, a 100-day personalized plan, supplement discounts, HSA/FSA eligibility, and personalized prescription therapies, described as clinician-guided metabolic, hormone and longevity care.

Superpower: a question answered on the day you have it

Both models put the next step on somebody else's clock: an appointment when Empirical Health's practice has one, or the 100-day plan that follows Hundred Health's single annual analysis. Superpower runs the year on yours. $349 a year covers an initial complete draw returning ~90 health metrics and a built-in follow-up draw later in the year that repeats ~60 key trackable markers, and the support around them is a 24/7 care team you message the day something comes up — a result you cannot place, a symptom in week three, a supplement you want checked before you start it, a number that moved the wrong way — rather than a slot in a practice's calendar or a step inside a hundred-day sequence. The same membership turns the results into a personalized action plan, the kind of read that led 60% of members to say Superpower identified something previously missed or overlooked by a doctor.

A plan you cannot ask questions about is a plan you end up following alone. Start your health journey with Superpower and keep the care team in reach for the whole year.