Hundred Health vs OneTwenty

What is Hundred Health, and what is OneTwenty?

Hundred Health sells a health strategy built from your own data. Blood work, imported medical records, and wearable streams feed a protocol that runs for 100 days.

OneTwenty brands its membership "The Full Forever Physical". Bloodwork repeats every quarter, devices sync daily, and the protocol shifts as the numbers do. The company is still in a founding-member phase, and its site says founding pricing ends at public launch.

Both pair labs with wearables and a plan, and both offer prescriptions and supplements. The difference is rhythm: one annual panel at Hundred, four draws at OneTwenty.

What does Hundred Health include?

A Hundred Health membership covers 100+ lab tests each year, medical-record import, connected wearables, a dashboard that shows biological age, and the 100-day protocol.

Hundred lays out its model in three steps:

1. We build your complete health record — Blood is drawn at a partner lab or at home, and Hundred gathers older records, labs, and imaging while your devices connect.
2. Your health results, finally explained — Labs and wearable readings are analyzed together and benchmarked against peers, with physician-led insights.
3. Get your 100-day action plan — A clinician-built protocol covers nutrition, supplements, exercise, and lifestyle.

Records come in from 450+ health systems. According to the FAQ, members do not currently talk to a physician inside the app, though clinicians train and audit the AI behind it.

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What does OneTwenty include?

OneTwenty's annual fee buys four panels, daily device syncing, a dedicated health coach, an AI assistant, and a 0-to-100 One Health Score built on the American Heart Association's Life's Essential 8. Supplements and medications are billed on top.

The company describes five steps:

1. Sign Up → Schedule Labs — An independent licensed provider orders a comprehensive baseline panel, drawn at home or at a lab near you.
2. Wearables — Connect the device you already own.
3. Connect Your Scale and Blood Pressure Monitor — Body composition and heart readings flow in automatically.
4. Get Your Action Plan — Labs and body data combine into a protocol covering training, sleep, nutrition, and supplements.
5. Track in Real Time + Get Adjusted — The dashboard refreshes daily and the protocol follows it.

Members can import their full history from any lab, including Function Health. OneTwenty calls itself a health optimization membership rather than a medical practice, and independent licensed providers handle anything clinical.

What biomarkers do Hundred Health and OneTwenty measure in 2026?

Hundred Health publishes 100+ lab tests for one annual draw. OneTwenty lists 101 markers at baseline, then a custom panel of 20 to 40 markers each quarter, for 161 to 221 lab results a year.

Counted off each company's published list, both sides include urinalysis, and both counts mix direct measurements with calculated values.

Hundred's first draw lists more markers than OneTwenty's baseline. OneTwenty's quarterly panels retest only what needs watching, so its yearly total depends on the baseline. Hundred tags some markers as add-ons:

• Heart and lipids — Lipoprotein(a), ApoA1, LDL particle number, and oxidized LDL.
• Nutrients and toxins — Omega fatty acids, homocysteine, zinc, and heavy metals.
• Thyroid and stress — Thyroid antibodies, free T3, cortisol, and DHEA sulfate.

Neither membership sells scans today. Hundred's FAQ lists Galleri, Prenuvo, and DEXA as planned for 2026. OneTwenty keeps no add-on test catalog at all; its extras are its own supplement pack, medications, and devices.

What are the official 2026 membership prices for Hundred Health and OneTwenty?

Hundred Health costs $199 a year. OneTwenty charges founding members $499 a year, rising to $749 in New York and New Jersey, and the brand says that pricing ends at public launch.

At Hundred, optional add-on tests can carry separate fees, and New York and New Jersey members pay up to $248 a year toward the lab. OneTwenty's walk-in draw is included, an at-home phlebotomist costs $99, and its Custom Packs start at $67 a month.

OneTwenty renews at the then-current rate. Its payment policy allows cancellation within 7 days of purchase, less a 3% processing fee, if no services have started. HSA/FSA funds work with both, Hundred's care program included, and OneTwenty says final eligibility depends on your plan.

How often does each one test?

Hundred tests once a year, and OneTwenty tests four times.

Hundred's membership includes its lab tests annually, and the FAQ recommends a full retest every 100 days. OneTwenty's How It Works page promises focused panels every 90 days on the markers that need watching.

For a member watching one change closely, such as a new supplement, OneTwenty's schedule produces data sooner. Hundred's single panel reads 113 to 116 markers in one draw.

Who walks you through the results?

Hundred's protocol is clinician-built, and members read it in the app. OneTwenty assigns a dedicated health coach, and its AI assistant answers questions instantly and flags anything worth a closer look.

Hundred shows early results within 24 hours, though the full panel takes about two weeks. OneTwenty's results typically arrive in about a week.

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One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

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Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

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What do prescriptions and supplements cost at each?

Hundred offers discounts on supplements and a separately priced prescription program, and OneTwenty bills monthly on top.

Hundred's member marketplace sells supplements at up to 20% off retail. Its care program handles weight-loss medication from $99 a month, priced apart from the membership. A consultation has to come first, and Alaska, Illinois, Mississippi, and New Jersey sit outside its reach.

OneTwenty sells a personalized daily pack built from your latest panel. Its medications and hormone therapy start at $49 a month through independent licensed providers, and the brand ranks them last: lifestyle, then supplements, "and only then medication if your data and a provider support it." A prescription opens at its lowest dose, is reviewed monthly, and adds its tracked markers to the next quarterly panel.

Where are Hundred Health and OneTwenty tests available?

Hundred Health draws blood at 5,000+ partner labs or at home. In-lab visits are unavailable in Hawaii, North Dakota, South Dakota, and West Virginia.

OneTwenty is available in 49 states, all but Rhode Island. In New York and New Jersey, collection laws raise the fee, and the membership costs $749 there.

Who is Hundred Health best for, and who is OneTwenty best for?

Hundred Health is best for:

• People who want a lower flat price and one broad annual panel.
• People who want to import records from 450+ health systems.
• People who want supplement discounts rather than a monthly pack.

OneTwenty is best for:

• People who want a draw every quarter and a coach to talk to.
• People who want a scale and blood pressure monitor feeding the same dashboard.
• People comfortable paying a founding-member price before public launch.

The bottom line

Hundred Health is the lower-priced option, with one broad annual panel, supplement discounts, and a separately priced prescription program. OneTwenty tests four times a year and pairs the results with a coach, though its $499 is a founding-member price that ends at public launch.

Both bill extras outside the fee. Hundred's weight-loss care program starts at $99 a month, while OneTwenty adds Custom Packs from $67 and medications from $49 a month to its $499. Neither membership sells scans today.

Superpower's $199 a year in most states matches Hundred and costs less than OneTwenty's $499 founding price, which covers four draws to Superpower's one. Scans are on sale in its marketplace now, from DEXA to whole-body MRI, beside add-on tests, supplements at up to 20% off, and prescriptions available when clinically appropriate, priced separately. Superpower AI builds a Superpower Protocol from 100+ biomarkers in one draw, your wearables, and your records. Superpower says 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.