Hone Health vs SiPhox Health

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Hone Health
SiPhox Health
Superpower Logo
Annual baseline test
50+ lab tests on Basic and Premium*
31 biomarkers per kit, up to 62 with the Ultimate 360 upgrade*
100+ biomarkers in one draw*
Cost
Premium $1,860/year ($155/month) plus a $65 initial test; Basic $300/year ($25/month) plus a $25 initial test and $25 onboarding fee; medication extra
$99 for the first kit, then $124 per kit plus $25 shipping, renewing monthly, quarterly, or every 6 months
$199/year
Testing locations
2,000+ partner labs, at-home GetLabs visit, or men's at-home kit
At-home upper-arm kit, no lab visit
2,000+ partner labs or at-home draw (+$119)
New York and New Jersey access
Not available in New Jersey; New York carries Basic and Premium
New Jersey served; New York not served
+$200 to cover state fees
Follow-up test
Retest every 3 months (Premium) or 6 months (Basic)
Another kit every month, quarter, or 6 months, as you choose
Not included
Care model
Physician consults included on Premium, $75 to $100 on Basic
Action plan and Sai AI assistant; 1:1 coaching sold as a $50 credit
AI and care team support on demand, year-round
Prescription access
Core to the product; medication priced separately
Heart and Metabolic Program members only, through an independent provider group
Through the marketplace, when clinically appropriate, priced separately
Access to peptides
Not included
Supplements
First-party storefront with nine own-brand products
Supplement recommendations inside the report
Curated marketplace with member-exclusive pricing
Biological age tracking
Not included
Results turnaround
About 10 business days at a lab, then 1 to 2 days of physician review
7 to 10 days after the sample reaches the lab
Within 10 days of the draw
Start testing

*Hone Health's count is the 50+ biomarkers it lists for Basic and Premium, retested every 6 months or every 3 months. SiPhox Health's counts are per kit: 31 on Longevity Essentials and 62 on Ultimate 360, a +$125 upgrade. Both include direct laboratory measurements and calculated metrics, and neither list includes urinalysis. Comparison based on publicly available information as of October 30, 2026.

Key takeaway:

Hone Health ($300 to $1,860/yr before medication) is a physician-led clinic where a lab draw leads into prescription care. SiPhox Health ($99 first kit, then $124) is at-home testing with a needle-free upper-arm device, on a schedule you pick. If you want more than a clinic or a kit in the mail, Superpower ($199/yr) goes beyond biomarker testing to be a true home for health. It adds a 100+ biomarker lab draw and a member marketplace, with Superpower AI turning every result into a full action plan.
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What is Hone Health, and what is SiPhox Health?

Hone Health is a telehealth clinic. Lab testing feeds physician consults, and the plan can include prescription medication shipped to you.

SiPhox Health runs its tests at home. Its homepage promises "No needles," "No lab visits," and "No monthly fees," and a kit arrives on whatever schedule you set.

They differ most on who is in the room when the blood comes out. At Hone it is usually lab staff or a visiting phlebotomist, and at SiPhox it is you.

What does Hone Health include?

Hone sells three tiers. The men's Plus tier is a hormone program built on a small at-home kit, while Premium and Basic both test 50+ biomarkers at a partner lab. Plus covers 8 to 11 biomarkers and bills $135 a month after a $45 start.

Premium follows a four-stage path:

  1. Measure what matters — A comprehensive biomarker test at a lab starts things off.
  2. Consult with a licensed physician — You review labs, symptoms, and goals on a private video call.
  3. Ongoing personalized care — Repeat labs and clinician support carry on, alongside medication and supplements.
  4. Optimize your health — A retest and clinician meeting come around every 3 months.

Basic runs a lighter path of three stages: review your results on a dashboard, build a longevity protocol from the data, and monitor changes over time. Basic charges for each physician consult: $75 for men and $100 for women.

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What does SiPhox Health include?

A SiPhox membership covers an at-home kit with a choice of four included panels, a health report with an action plan, supplement recommendations, and the Sai AI assistant. You can also upload outside lab results without limit, and the app includes a body composition scan.

SiPhox lays out a four-step process:

  1. Join SiPhox Health — You pick a testing pace: monthly, quarterly, or every 6 months.
  2. Select your health focus — Longevity Essentials, Heart & Metabolic, Hormone Focus, and Thyroid Focus are each open to you, and you can switch later.
  3. Test at home, painlessly — The EasyDraw device takes a small upper-arm sample in about 5 minutes, with live 1:1 support as you collect.
  4. Get insights & optimize — Results come with analysis, recommendations, and an action plan, and Sai answers follow-up questions.

Every plan also reports BioAge and Heart & Metabolic Age scores.

What biomarkers do Hone Health and SiPhox Health measure in 2026?

Hone Health lists 50+ biomarkers on one comprehensive panel. SiPhox Health's panel comparison page gives 31 biomarkers on Longevity Essentials and 62 on Ultimate 360, each counted per kit.

Hone HealthSiPhox Health
Initial draw63 biomarkers listed across both sexes (51 distinct and 12 calculated)31 biomarkers (19 distinct and 12 calculated) on Longevity Essentials; 62 biomarkers (42 distinct and 20 calculated) on Ultimate 360
Follow-up drawRetest every 3 months (Premium) or 6 months (Basic)Another kit on your chosen cadence, with the panel swappable
Headline count50+ lab tests31 to 62 biomarkers per kit

SiPhox's other included panels are narrower: Heart & Metabolic at 28, Thyroid Focus at 21, and Hormone Focus at 14. Hone's list is longer than any of them, and the Ultimate 360 upgrade, at 62 per kit, brings SiPhox close to Hone's count. Neither list carries urinalysis, so the counts share a basis.

SiPhox's optional extras attach to a kit:

Hone's scan add-ons:

What are the official 2026 membership prices for Hone Health and SiPhox Health?

Hone Health's Premium plan is a $1,860-a-year program billed monthly, and Basic is $300, both before medication. SiPhox Health charges $99 for every new member's first kit, then $124 per kit plus $25 shipping.

SiPhox's annual cost depends on the pace you choose. Monthly, quarterly, and twice-yearly cadences mean 12, 4, or 2 kits a year. The $125 figure belongs to the Ultimate 360 upgrade, not to the base kit.

Hone's $65 initial test lifts Premium's first year to $1,925, and a $25 test plus a $25 onboarding fee lift Basic's to $350. SiPhox says all of its products are HSA/FSA eligible, and Hone provides receipts for plan submissions.

How does each company collect your blood?

Hone's default is a lab draw. A GetLabs phlebotomist can visit your home or workplace, free for initial labs on the Optimization programs, and men on the hormone plan can use an at-home kit. Women test at a lab.

SiPhox's EasyDraw device collects from the upper arm, and the sample leaves by prepaid FedEx label the same day. SiPhox says its lab results show a 95% to 99% correlation with standard venous draws. Canadian members use a finger-prick method instead.

Who guides you after the results, and what do they sell?

Hone's physicians interpret results and write prescriptions, with programs spanning hormones, thyroid, weight, heart health, sexual health, and longevity. Its storefront sells nine own-brand supplements, and medication is priced separately. A man starting hormone therapy also pays for a confirmatory lab, $25 at a lab on Premium, or $45 at a lab and $80 at home on Plus.

SiPhox's guidance is a report and Sai. Results go through expert review, and the assistant answers questions in the app. A $50 coaching credit buys a 30-minute video call or a written plan, and SiPhox says coaching is not medical advice. SiPhox itself does not prescribe: members of its Heart and Metabolic Program can get medication management from an independent provider group. Supplements arrive as recommendations, and its shop sells none.

How often can you test, and how fast do results arrive?

SiPhox lets you choose the pace, and Hone sets it by tier. Premium retests every 3 months and Basic every 6.

Hone needs about 10 business days to process a lab draw, then a 1 to 2 business day physician review. SiPhox quotes 7 to 10 days counted from lab receipt, and ships the kit within 3 days of your order.

Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

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Where are Hone Health and SiPhox Health tests available?

Hone's availability table shows no plan in 13 states and Washington, D.C., New Jersey included. New York carries every plan except men's Plus.

SiPhox serves every state except Hawaii and New York, and it serves Canada. Its footer calls the service wellness-only.

Who is Hone Health best for, and who is SiPhox Health best for?

Hone Health is best for:

  • People who want a physician-led plan with prescription medication available.
  • People who want to test at a lab or with a visiting phlebotomist.
  • People who live in a state where Hone has a plan.

SiPhox Health is best for:

  • People who want a needle-free kit at home and no lab visit.
  • People who want to pick a testing pace and swap panels over time.
  • People in states where Hone has no plan, such as New Jersey or Pennsylvania.

The bottom line

Hone Health fits people who want a physician and medication behind their labs. SiPhox Health fits people who want a needle-free kit at home, on a pace they set.

Both bill the next step separately. SiPhox's plan arrives as recommendations, with coaching sold as a $50 credit, while Hone bills medication on top of its monthly fee.

At $199 a year in most states, Superpower costs less than Hone Basic at $300 a year. Members book one draw of 100+ biomarkers at a partner lab, or at home for an added fee. Wearable data and medical records join those results in one Superpower AI. That AI drafts your Superpower Protocol and keeps coaching through AI and care team support. Prescriptions are available through the marketplace when clinically appropriate, priced separately. The same marketplace discounts supplements for members by up to 20% and lists add-on tests and scans. 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.

Frequently asked questions

References

  1. Hone Health. (2026). How it works. Hone Health.
  2. Hone Health. (2026). Biomarkers. Hone Health.
  3. Hone Health. (2026). Supplements for men. Hone Health Shop.
  4. Hone Health. (2026). Hone Health membership overview: Compare Basic, Plus, and Premium plans. Hone Health Help Center.
  5. Hone Health. (2026). Hone Basic membership: Longevity support without hormone therapy. Hone Health Help Center.
  6. Hone Health. (2026). Hone Premium membership: Full clinical insight for men. Hone Health Help Center.
  7. Hone Health. (2026). Hone Plus membership: Men's hormone replacement therapy with labs. Hone Health Help Center.
  8. Hone Health. (2026). Hone Men's Premium membership overview and payment breakdown. Hone Health Help Center.
  9. Hone Health. (2026). When will my results be available? Hone Health Help Center.
  10. Hone Health. (2026). How to complete your blood draw with Hone Health. Hone Health Help Center.
  11. Hone Health. (2026). Timely return of your at-home hormone lab panel. Hone Health Help Center.
  12. Hone Health. (2026). Lab process overview and FAQs. Hone Health Help Center.
  13. Hone Health. (2026). Hone Health service availability by state. Hone Health Help Center.
  14. Hone Health. (2026). Hone Prenuvo patient FAQ. Hone Health Help Center.
  15. Hone Health. (2026). BodySpec DEXA scans through Hone. Hone Health Help Center.
  16. SiPhox Health. (2026). At-home health testing. SiPhox Health.
  17. SiPhox Health. (2026). SiPhox Health vs Rythm Health. SiPhox Health.
  18. SiPhox Health. (2026). How it works. SiPhox Health.
  19. SiPhox Health. (2026). Panels. SiPhox Health.
  20. SiPhox Health. (2026). Panel comparison. SiPhox Health.
  21. SiPhox Health. (2025, November 13). How much does SiPhox Health cost? SiPhox Health.
  22. SiPhox Health. (2026). Frequently asked questions. SiPhox Health.
  23. SiPhox Health. (2026). Expert health coaching. SiPhox Health.
  24. SiPhox Health. (2026). Terms of service. SiPhox Health.
  25. SiPhox Health. (2026). State coverage. SiPhox Health.

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Chief Longevity Officer, Superpower

Dr. Leigh Erin Connealy

Dr. Leigh Erin Connealy, MD

Clinician & Founder of The Centre for New Medicine

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Physician & UCLA Medical School Professor, NYT bestselling author

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TestosteroneFree T4Vitamin DApoBHbA1cThyroid (TSH)hs-CRPFerritinCortisolFasting insulin

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We test 100+ biomarkers from a single blood draw each year. Your baseline test paints a comprehensive picture of your health, and your dashboard shows what’s working, what needs attention, and what to do next. Superpower AI and your care team help you take action across lifestyle, supplements, and treatments.

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Book your draw at any of 2,000+ partner labs or at-home. Results are typically ready in about a week and land in the Superpower app.