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Digestive & weight

What should I know about BPC-157 dosage?

No standard BPC-157 dosage has been set for people. See the reported 200-500 mcg daily range, the doses studies tested, and what to check on a product.

EvidenceLimited research
ClassSynthetic pentadecapeptide (gastric-derived)

Quick answer

No standard BPC-157 dosage has been established for people. Reported off-label protocols commonly cite 200-500 mcg per day by subcutaneous injection or by mouth, a range extrapolated informally from rodent doses. These are reported practice patterns rather than a standardized dose. Animal safety studies spanned 6 mcg/kg to 20 mg/kg. Three small peer-reviewed human studies covering 30 people tested fixed doses of 2-20 mg. BPC-157 is not an FDA-approved drug, has no established labeled route, and is prohibited in sport under WADA rules.

Published
November 4, 2026
Last updated
November 4, 2026

At a glance

ClassSynthetic pentadecapeptide (gastric-derived)
TakenUnder the skin/oral
In the USNot FDA-approved; PCAC voted favorably (Jul 2026) for 503A compounding, final FDA rule pending
EvidenceLimited research

Is there a standard BPC-157 dose?

No standard BPC-157 dosage has been established for people. Validated human dosing and long-term safety data1 are not yet available. Most BPC-157 findings come from laboratory and animal research. Peer-reviewed human research includes three small studies covering 30 people2. They reported symptom improvement in most participants, with no treatment-related adverse events.

BPC-157 is not part of any FDA-approved drug3 and has no USP or NF monograph, the official quality standard for a drug ingredient. No drug label sets a BPC-157 dose, route, or schedule.

Without a label, BPC-157 dose figures come from what users report.

What BPC-157 doses are reported?

Reported off-label BPC-157 protocols commonly cite 200-500 mcg per day4, given by subcutaneous (under-the-skin) injection or by mouth. These are reported practice patterns rather than a standardized dose.

The reported BPC-157 range was extrapolated informally from rodent doses4, without formal scaling between species. Dosing frequency and duration have not been established5, so the prescribing clinician sets the schedule.

Study-tested BPC-157 doses add a second record.

What BPC-157 doses have studies tested?

Most BPC-157 dosing studies gave animals doses by body weight6, while three peer-reviewed human studies used fixed doses of 2-20 mg.

Animal safety studies of BPC-157 spanned 6 mcg/kg to 20 mg/kg6 across intramuscular, intraperitoneal (into the abdominal cavity), intravenous, and oral routes. Musculoskeletal animal studies usually gave BPC-157 once daily, from a single dose up to 90 days of dosing7. FDA called the human BPC-157 doses it reviewed likely exploratory3, with short courses and small groups.

StudySpecies or populationRouteDose and unitDuration
Achilles tendon studyRatsIntraperitoneal (into the abdominal cavity)10 mcg/kg, 10 ng/kg, or 10 pg/kg8 body weightOnce daily, up to 14 days
Pharmacokinetic studyRats and dogsIntravenous and intramuscularSingle doses of 20-500 mcg/kg in rats9 and 6-150 mcg/kg in dogs; repeat doses of 100 mcg/kg in rats and 30 mcg/kg in dogsSingle dose, or once daily for 7 days
Preclinical safety program10Rats and dogsIntramuscular0.2, 1, or 4 mg/kg per day3 in rats; 0.1, 0.5, or 2 mg/kg per day in dogsDaily for 28 days
Knee pain chart review1116 people with knee pain followed up (17 charts reviewed)Intra-articular (into the joint) injection2-4 mg31-2 injections
Bladder pain pilot12 women with interstitial cystitisInjection into the bladder wall during cystoscopy10 mg total121 procedure
Intravenous safety pilot2 healthy adultsIntravenous infusion10 mg on day 1, then 20 mg13 on day 22 days
Rotator cuff repair pilot trialAdults after arthroscopic rotator cuff repairSubcutaneousDose amount not listed in the registryPlanned once daily for 90 days14; not yet recruiting, no results posted as of November 2026
Oral tablet trial, Phase 142 healthy volunteers (planned enrollment)Oral tabletPlanned single doses of 1, 3, or 6 mg15, then 3 mg every 8 hoursPlanned 2 weeks; status unknown since 2015, no results posted

Per-kilogram BPC-157 doses in animals do not translate directly into human doses4, so no weight chart for people follows from them. BPC-157 products add another variable, since they differ in form and strength.

What forms does BPC-157 come in?

BPC-157 is sold as injections, capsules, oral sprays, and nasal sprays3. FDA found no human absorption data3 for oral, subcutaneous, nasal, or skin use of BPC-157.

BPC-157 product strengths show what is sold, not a tested dose. A different route can change how much BPC-157 is absorbed. Research or experience with one route does not automatically describe another.

What to check on a BPC-157 product depends on its form.

FormWhat to check
InjectionIdentity, purity, and concentration1; vial strength (freeze-dried 6 mg and 10 mg vials3); sterility, bacterial endotoxins, and particles3; storage; and who prepared the product
Capsule or oral sprayThe exact BPC-157 form (free base or acetate salt), the strength in micrograms (500 mcg products sold3), and what supports its stability and absorption
Nasal sprayWhether the research being cited used a nasal route or a different product

Reconstitution means mixing freeze-dried BPC-157 with a specified amount of bacteriostatic water. A prescribing clinician sets the target dose, which the vial's strength and water volume turn into syringe units. Anti-doping rules add a separate limit on BPC-157 for competitive athletes.

The 2026 Prohibited List from the World Anti-Doping Agency (WADA) names BPC-157 as a non-approved substance (class S0), banned at all times16. Athletes subject to drug testing can face sanctions for BPC-157 use and should check current WADA and league rules.

Getting BPC-157 in 2026

Superpower will offer BPC-157 formulated in FDA-registered facilities in the US, backed by third-party lab testing, and distributed from US-licensed pharmacies. A licensed clinician will decide whether BPC-157 belongs in each person's health care. The Superpower peptide waitlist is open now.

BPC-157 has not been approved by FDA as a drug. In October 2026, the Department of Health and Human Services announced it does not intend to take enforcement action17 against state-licensed pharmacies compounding six peptides, BPC-157 among them, while the 503A Bulks List (the list of ingredients pharmacies may use in compounding) is finalized. Conditions of the interim policy18 include a patient-specific prescription and ingredients from FDA-registered facilities. A July 2026 FDA advisory committee recommendation to add BPC-157 to the list19 came first, and the rulemaking continues.

About BPC-157

More answers about BPC-157