Lifeforce vs OneTwenty

What is Lifeforce, and what is OneTwenty?

Lifeforce sells longevity medicine as a program: blood work, a clinician consult, a written health plan, and retests, with prescription access for members. The Core Annual plan pairs two draws a year with one consult, and the Monthly plan pairs four draws with four.

OneTwenty calls itself "a health optimization membership, not a medical practice." It starts with a 101-marker baseline, adds a targeted panel each quarter, and syncs device data in between. The company is still enrolling founding members ahead of its public launch.

Both promise a year of repeat measurement rather than a single snapshot. They split on who guides you through the numbers: a clinician on a scheduled call at Lifeforce, a coach and an AI assistant at OneTwenty.

What does Lifeforce include?

A Lifeforce membership includes scheduled blood draws, clinician consults, a personalized health plan, and access to prescription medications, in quantities that depend on the plan you pick.

Lifeforce lays the program out as a four-step process:

1. Schedule your blood draw — A phlebotomist collects the sample, at home or at a lab.
2. Meet 1:1 with your clinician — A health questionnaire comes first, then a virtual visit covers results and goals.
3. Get your custom plan — A health coach supports the program, and the Monthly plan lists unlimited coaching.
4. Retest and refine — A draw every 3 to 6 months shows what moved and adjusts the plan.

Results take 10-14 business days from the test date. Members also get 30% off Lifeforce's own supplements, and medications are priced as separate products.

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What does OneTwenty include?

OneTwenty's membership bundles quarterly draws, a coach, an AI health assistant, and device syncing, with supplements and medications billed on top.

OneTwenty describes a five-step process:

1. Sign up — One annual membership at founding-member pricing.
2. Schedule labs — A walk-in draw costs nothing extra, and an independent licensed provider orders the panel.
3. Connect devices and past labs — Link your wearables and upload earlier results.
4. Results plus action plan — Each marker gets an explanation, followed by a protocol.
5. Retest quarterly — Focused panels every 90 days cover the markers worth watching.

Results typically arrive in about a week. Its AI assistant monitors device and lab data as it arrives, and it sends you back to your own doctor for anything medical. The membership's headline number is One Health Score, a 0 to 100 reading built on the American Heart Association's Life's Essential 8 rather than on biological age.

What biomarkers do Lifeforce and OneTwenty measure in 2026?

Lifeforce advertises 50+ biomarkers per draw, while OneTwenty opens with 101 markers and then narrows to 20 to 40 each quarter.

Lifeforce's published list runs to 60 biomarkers with no urinalysis. OneTwenty's list includes 21 urine results.

OneTwenty's baseline is the longer list, and its quarterly panels are targeted retests rather than repeats of all 101. Lifeforce reruns its whole panel at every draw, apart from Lp(a), which it considers genetically determined.

Lifeforce adds add-on panels at extra cost:

• Blood panels — Heavy Metals, Metabolic Health, and Cardiovascular Health, $200 each.
• Brain Protection — $850 for the initial test and $700 for a follow-up.

OneTwenty keeps its extras inside the retest loop:

• Quarterly panels — 20 to 40 markers each, picked from your baseline and included in the membership.
• Device metrics — 22 readings streaming from your wearables, kept apart from lab results.
• Medication markers — a prescription adds the markers its prescriber watches to your next quarterly panel, and the brand sells no standalone add-on test.

What are the official 2026 membership prices for Lifeforce and OneTwenty?

Lifeforce's Core Annual plan is $599, and its Monthly plan opens at $199 for the first month, then $149 a month. OneTwenty costs $499 a year at founding-member pricing, which ends at public launch.

Paying Lifeforce's Monthly plan month by month adds up to $1,838 in the first year. Prepaying that plan costs $1,449 for the year.

OneTwenty charges $749 in New York and New Jersey, bills annually, and renews at the rate in force at renewal. Lifeforce's first at-home visit on Core Annual is free, while an at-home draw at OneTwenty is $99.

Both are HSA/FSA eligible. Lifeforce works through Truemed and a Letter of Medical Necessity, and OneTwenty says final eligibility depends on your plan.

How do the draw schedules and collection options differ?

Lifeforce schedules two or four draws a year depending on the plan, while OneTwenty builds four into its single membership.

Lifeforce lets members pick a walk-in lab or an at-home phlebotomist, though residents of New York, New Jersey, and Rhode Island get in-home draws only. Core Annual makes the first at-home visit free, with the second draw at a lab. Service covers the 48 contiguous states, and North Dakota is excluded from testing.

OneTwenty books every draw through a national lab network, with a walk-in at no extra cost or a phlebotomist at your door. Membership is open in 49 states, all except Rhode Island. New York and New Jersey fall outside that network under state collection laws, so the higher price there covers the same four panels, with at-home draws required.

On the annual plans, OneTwenty includes four draws and Lifeforce two, so cadence is the practical difference if you want to watch markers move through the year.

Who explains your results at Lifeforce and OneTwenty?

Lifeforce puts a clinician on a booked call, and OneTwenty pairs you with a coach backed by independent providers.

Lifeforce's consult is a 45-minute visit by telehealth. Before it, a clinician's first look posts to the portal inside 48 hours of the lab report. Between visits, medication and protocol questions go to a medical operations team that replies in 1-2 business days.

OneTwenty assigns a dedicated health coach who walks you through each panel. Independent licensed providers order the labs and handle anything clinical, since OneTwenty positions itself as a membership rather than a medical practice.

If you want a dated appointment with a clinician, Lifeforce is built for it. If you want a standing channel that follows your data, OneTwenty is.

What do supplements and prescriptions cost at each?

Both sell supplements and medications, and both charge for them on top of the membership.

Lifeforce members get 30% off its own supplements, though one-time orders cost 20% more than subscription orders. Its pharmaceuticals collection prices each medication as its own product, open to members only and contingent on blood test results and a clinician video consult. Orders run on a recurring subscription only.

OneTwenty's Custom Packs deliver one daily pack formulated from your newest panel, from $67 a month. Medications and hormone therapy start at $49 a month. The brand ranks lifestyle and supplements first, "and only then medication if your data and a provider support it."

The membership figure on either site therefore understates a year that includes supplements or medications.

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Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

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Who is Lifeforce best for, and who is OneTwenty best for?

Lifeforce is best for:

• People who want a booked 45-minute clinician consult after each round of results.
• People who want a phlebotomist to come to them, with the first at-home visit free on Core Annual.
• People who want access to hormone therapy alongside their testing.

OneTwenty is best for:

• People who like a retest every quarter, narrowed to the markers that matter.
• People who want device data streaming in beside their labs.
• People comfortable joining early at founding-member pricing.

The bottom line

Lifeforce fits someone who wants a clinician conversation on the calendar and a phlebotomist at the door. OneTwenty fits someone who wants four draws a year, a coach, and a retest that narrows to the markers worth watching.

Both models also keep extra testing narrow. Lifeforce sells four add-on panels, from $200 each, and OneTwenty's extra markers come only through its quarterly retests.

Superpower costs $199 a year in most states, which is lower than both Lifeforce's $599 and OneTwenty's $499 founding-member price. That one membership measures 100+ biomarkers in a single draw. Results, wearable data, and medical records all flow into one Superpower AI, which drafts your Superpower Protocol and revises it as new data arrives. Inside the marketplace, supplements run up to 20% off and add-on tests and scans are bookable, with prescriptions available when clinically appropriate, priced separately. 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.