Function Health vs OneTwenty

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Function Health
OneTwenty
Superpower Logo
Annual baseline test
160+ lab tests across two draws*
161 to 221 lab results a year across four draws*
100+ biomarkers in one draw*
Cost
$365/year
$499/year founding-member pricing ahead of public launch, with supplements and medications billed on top
$199/year
Testing locations
2,000+ partner labs or at-home draw (fee varies by location)
2,000+ partner labs or at-home draw (+$99)
2,000+ partner labs or at-home draw (+$119)
New York and New Jersey access
Charged at the facility on the day of the draw
$749 per year founding-member pricing, at-home draws required
+$200 to cover state fees
Prescription access
Not offered
Medications and hormone therapy through independent licensed providers, from $49 a month
Through the marketplace, when clinically appropriate, priced separately
Access to peptides
Not included
Supplements
SuppCo guidance tied to your biomarker data, no member-priced storefront
Custom Packs built from your labs, from $67 a month
Curated marketplace with member-exclusive pricing
Follow-up test
Partial redraw retesting ~60 biomarkers, included
Targeted panel of 20 to 40 markers each quarter, included
Not included
Action plan
Clinician-reviewed analysis and action plan
Health coach and AI health assistant, with independent providers handling anything clinical
Superpower Protocol, built from labs, wearables, and medical records
Wearable integration
Data synced via connected apps
Oura and Withings connect directly, other devices through Apple Health or Google Fit
Direct integration with Apple Health, Whoop, Oura, and more
Results speed
First results typically within 48 hours of testing
About one week
Within 10 days of the draw
Start testing

*Includes direct laboratory measurements and calculated health metrics. Function Health's count combines an initial draw with a partial follow-up draw that repeats around 60 of the same markers. OneTwenty's range is a 101-marker baseline plus three targeted panels of 20 to 40 markers each. Comparison based on publicly available information as of October 30, 2026.

Key takeaway:

Function Health ($365/yr) bundles two draws, 160+ lab tests, and a clinician-reviewed action plan into one yearly fee. OneTwenty ($499/yr founding-member pricing ahead of public launch) leads with "See everything. Change what matters.": quarterly panels, daily device sync, and a health coach, with supplements and medications billed on top. If you want scans and add-on tests in the same membership as your supplements and compounded prescriptions (like peptides), Superpower ($199/yr) goes beyond biomarker testing to be a true home for health. Its single draw covers 100+ biomarkers, which Superpower AI combines with your wearables and records into one action plan.
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What is Function Health, and what is OneTwenty?

Function Health and OneTwenty both sell blood testing as a yearly membership, and they differ in how often they test and what the membership can prescribe.

Function Health runs two draws a year and has its clinicians turn the results into an analysis and action plan. It does not offer prescriptions.

OneTwenty brands its membership "The Full Forever Physical": bloodwork every quarter, devices syncing every day, and a protocol that updates with both. It is selling founding-member pricing ahead of its public launch.

They diverge on prescriptions: OneTwenty offers medications and hormone therapy through independent providers, and Function does not.

What does Function Health include?

The $365 Function Health fee buys two draws with 160+ lab tests between them, a plan that clinicians review, and a results dashboard.

The brand lists four stages:

  1. Schedule tests — You share a health history, and a first draw gets booked.
  2. Get insights — Clinicians check the numbers against your history and call out what deserves attention.
  3. Take action — Another test 3 to 6 months later shows whether things moved.
  4. Monitor for life — A running record brings out patterns and early signs.

An annual draw of about 115 biomarkers comes first, then a mid-year draw that repeats roughly 60 of them at no added cost. Function also runs a private AI chat for questions about results, and its SuppCo arm offers supplement guidance rather than a store.

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What does OneTwenty include?

OneTwenty's membership includes a baseline panel, quarterly targeted retests, a dedicated health coach, an AI health assistant, and an action plan built from labs and device data.

OneTwenty's five steps are:

  1. Sign Up → Schedule Labs — Baseline blood work at home or at a nearby lab, ordered by an independent licensed provider.
  2. Wearables — You connect the device you already own.
  3. Connect Your Scale and Blood Pressure Monitor — Body composition and heart readings flow in on their own.
  4. Get Your Action Plan — Labs and body data become a protocol covering training, sleep, nutrition, and supplements.
  5. Track in Real Time + Get Adjusted — A daily dashboard updates, and the protocol changes with it.

OneTwenty describes itself as "a health optimization membership, not a medical practice." Providers handle anything clinical, and the AI assistant points you to your own doctor when something needs medical attention.

What biomarkers do Function Health and OneTwenty measure in 2026?

OneTwenty's baseline panel is close in size to one Function draw, and the difference between them lies in what follows it.

Function HealthOneTwenty
Initial draw116-118 biomarkers (102-103 distinct and 14-15 calculated)94-97 biomarkers (86-89 distinct and 8 calculated)
Follow-up drawRetests ~60 markers already on the annual panel, includedThree targeted panels of 20 to 40 markers each, included
Headline count160+ lab tests across two draws161 to 221 lab results a year

OneTwenty's range of 161 to 221 depends on which markers your baseline flags for retesting. Both counts include urinalysis and calculated values.

Function's add-ons include:

  • Heart, thyroid, and autoimmunity — Thyroid, celiac, and autoimmunity extensions alongside heart and metabolic panels.
  • Hormones, toxins, and nutrients — Extended hormone health, heavy metals, PFAS, and extended vitamins.
  • Cancer, brain, and allergies — The GRAIL cancer test, Alzheimer's detection, and ApoE risk.
  • Scans — Heart CT, lung CT, and MRI through Ezra.

OneTwenty sells no add-on tests. Its add-ons are medications, supplements, and devices, each billed on top of the annual membership:

  • Custom Packs — A daily supplement pack with 63 ingredients across eight categories, re-formulated each quarter.
  • Medications — Prescribed by independent providers, with the markers they track added to your next quarterly panel.
  • Devices — Extra monitors sold at discounted member pricing.

What are the official 2026 membership prices for Function Health and OneTwenty?

Function Health costs $365 a year. OneTwenty lists $499 a year as founding-member pricing, and its pricing card says that rate ends at public launch.

Function is the lower of the two annual prices, though OneTwenty's fee covers four panels to Function's two draws.

New York and New Jersey members pay $749 a year in founding-member pricing at OneTwenty, which covers the at-home draws required there. Function collects its state fee at the facility on draw day. Elsewhere, OneTwenty's walk-in draw is free and an at-home phlebotomist adds $99, where Function's at-home option is limited to select locations at fees that vary. Both memberships are HSA/FSA reimbursement eligible, with conditions at OneTwenty.

Prescriptions and supplements on top of the membership

OneTwenty offers medications and hormone therapy, and Function Health does not.

OneTwenty prices medications from $49 a month on top of the membership, across eight areas that run from mental health to skin and hair. The brand puts lifestyle first, then supplements, "and only then medication if your data and a provider support it." Medications bill monthly or quarterly and ship from independent licensed pharmacies.

Supplements follow the same pattern. OneTwenty's Custom Packs from $67 a month are its own pack, cut from your latest panel. Function's SuppCo links supplement advice to your results without a pack or a store.

Four quarterly panels versus two draws

OneTwenty tests every 90 days, and Function Health tests twice a year.

OneTwenty's retests are focused panels every 90 days on the markers that need watching, and device data arrives between them. Function's second draw rechecks about 60 markers around mid-year.

More frequent draws catch change sooner. Fewer draws suit people who retest when they change something.

Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

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How do Function Health and OneTwenty turn results into a plan?

Function Health's plan comes from clinician review, and OneTwenty's comes from a coach, an AI assistant, and your device data.

Function's first results typically arrive within 48 hours of testing. Function gives no timeline for its analysis and action plan, though one review site cites three to four weeks.

OneTwenty's results typically take about a week. The AI assistant monitors incoming data and flags anything worth a closer look, and your coach walks you through the panel. OneTwenty condenses every marker and device reading into a 0-to-100 One Health Score, modeled on the American Heart Association's Life's Essential 8.

Where are Function Health and OneTwenty tests available?

Function Health operates 2,000+ draw locations in 48 states, with Hawaii, Rhode Island, and Puerto Rico the exceptions.

OneTwenty covers 49 states, skipping only Rhode Island. A higher fee applies in New York and New Jersey, where collection laws rule out its usual national lab network.

Who is Function Health best for, and who is OneTwenty best for?

Function Health is best for:

  • People who pay $365 for two draws a year.
  • People who want biological age measured with each draw.
  • People who want first results within 48 hours of testing.

OneTwenty is best for:

  • People who want quarterly retests and daily device data.
  • People who want a coach and prescriptions through independent providers.
  • People who want devices such as Oura and a smart scale feeding the same plan.

The bottom line

Function Health and OneTwenty both build a plan from repeated blood work. Function does it with two draws, a Biological Age test, and clinician review for $365. OneTwenty does it with quarterly panels, daily device data, a coach, and access to prescriptions through independent providers, at founding-member pricing of $499 ahead of its public launch.

Both models bill the extras separately. Function's add-on panels and scans, and OneTwenty's packs from $67 a month and medications from $49 a month, all sit outside the annual fee.

Superpower folds the next steps into $199 a year in most states, to Function's $365 and OneTwenty's $499 founding rate, the lowest of the three. Supplements sit in the marketplace at up to 20% off, rather than a pack billed monthly, next to add-on scans such as DEXA, VO2 max, and whole-body MRI, plus brain, genome, and gut tests. Prescriptions are available there when clinically appropriate, priced separately. Superpower AI builds your Superpower Protocol from your labs, wearables, and medical records, and revises it as new data arrives, with AI and care team support whenever questions come up. Superpower reports that 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.

Frequently asked questions

References

  1. Function Health. (2026). Pricing. Function Health.
  2. Function Health. (2026). Frequently asked questions. Function Health.
  3. Function Health. (2026). How it works. Function Health.
  4. Function Health. (2026). What we test. Function Health.
  5. Function Health. (2026). SuppCo. Function Health.
  6. OneTwenty. (2026). OneTwenty: Longevity powered by data. OneTwenty.
  7. OneTwenty. (2026). How it works. OneTwenty.
  8. OneTwenty. (2026). What we test. OneTwenty.
  9. OneTwenty. (2026). Payment policy. OneTwenty.
  10. OneTwenty. (2026). Medications. OneTwenty.
  11. OneTwenty. (2026). Supplements. OneTwenty.
  12. Crown Counseling. (2026, September 26). Function Health vs Superpower. Crown Counseling.
  13. Blood Test Comparison. (2026, September). Function Health review. Blood Test Comparison.

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Clinician & Founder of The Centre for New Medicine

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Physician & UCLA Medical School Professor, NYT bestselling author

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Superpower health membership

Find early signs of 1,000+ conditions from a single blood draw - then act on what you find.

$199

/year*

100+ biomarkers from a single blood draw

Personalized plan that turns results into action

Superpower AI and on-demand care team

Results in 10 days or less

At-home or 2,000+ labs nationwide**

Yearly membership$0.55 / dayHSA/FSA eligible

*Pricing may vary for members in New York and New Jersey

**At-home labs for an additional cost

What we test

TestosteroneFree T4Vitamin DApoBHbA1cThyroid (TSH)hs-CRPFerritinCortisolFasting insulin

60%

found something a doctor missed

93%

rated it more useful than their checkup

77%

found something new in their results

Superpower member survey, 90 days post action plan (n=143).

How does the Superpower membership work?

We test 100+ biomarkers from a single blood draw each year. Your baseline test paints a comprehensive picture of your health, and your dashboard shows what’s working, what needs attention, and what to do next. Superpower AI and your care team help you take action across lifestyle, supplements, and treatments.

Can I cancel anytime?

Yes. You can cancel anytime, no fees. Your membership stays active through the end of your paid year.

How often should I test?

Your membership includes two blood tests per year: one to establish your baseline, and one to see whether your plan improved biomarkers that were out of range or not yet optimized. You can add other diagnostics anytime through the app or with help from your care team.

When will I get my results?

Book your draw at any of 2,000+ partner labs or at-home. Results are typically ready in about a week and land in the Superpower app.