Key takeaway:
What is Empirical Health, and what is Rythm?
Empirical Health is a heart-focused panel with a doctor attached. You visit a lab once, and a physician-interpreted report arrives with your risk scores.
Rythm calls itself "the world's easiest blood test." A kit arrives at your door each month, you collect a sample at home, and results follow in the app.
They differ most on where the blood is drawn, and on how often.
What does Empirical Health include?
The $190 panel includes 100+ biomarkers from one lab visit, heart risk scores in the app, and Empirical Pro for tracking trends.
Empirical describes its approach in three steps:
- Measure — Track 100+ biomarkers, including ApoB and Lp(a), at one of 2,200 testing sites.
- Predict — Estimate how your lifetime risk of heart disease responds to lifestyle changes.
- Prevent — Follow a custom nutrition plan and exercise routine built from your numbers.
Most results arrive within 3-5 business days. The $399 Advanced program stretches the offer across 12 months. Two retests, at 3 and 9 months, come with it, along with a video appointment with a board-certified doctor.
What does Rythm include?
Rythm is a monthly subscription at $79 a test. Each kit comes with free pick-up, biomarker explanations, an AI Coach with no usage limit, and a Rythm Score once your first test is complete.
Rythm's homepage lists three steps:
- At-Home Test — Collect a small capillary sample at home with a Tasso+ device.
- Send — Mail the sample back, or use the complimentary FedEx pick-up.
- Results — Receive them within 2 days of the sample reaching the lab.
The lab is Rythm's own, CLIA-certified and CAP-accredited. Before results are released, a state-licensed physician signs off. That is a lab release step and does not put a physician on call.
What biomarkers do Empirical Health and Rythm measure in 2026?
A single Empirical draw measures far more markers than a single Rythm kit, and Rythm repeats its kit up to twelve times a year. Empirical's count includes 26 urine items, while Rythm's list carries no urinalysis.
| Empirical Health | Rythm | |
|---|---|---|
| Initial draw | 85 lab biomarkers (72 distinct and 13 calculated) | 27-28 biomarkers (21-22 distinct and 6 calculated) |
| Follow-up draw | Repeat testing at 3 and 9 months, Advanced program only | A new kit each month by default |
| Headline count | 100+ biomarkers on one draw | 25+ biomarkers per kit |
Rythm's published list names 30 biomarkers across six categories, split into separate men's and women's panels because one collection limits how many markers fit.
Beyond the base panels, the two differ:
- Empirical Health — The Advanced program adds repeat testing and the doctor visit.
- Rythm — No add-on tests yet, with an add-on option on its roadmap.
What are the official 2026 membership prices for Empirical Health and Rythm?
Empirical Health costs $190 once, or $399 for the Advanced program. Rythm costs $79 a month, plus shipping and tax. Twelve kits at $79 come to $948 before shipping and tax.
Rythm renews every 30 days. Members can skip up to 90 days without being charged, and first-test discounts change from page to page. A 90-day money-back guarantee applies to first-time purchases.
Residents of New York and New Jersey pay Empirical an extra $99 lab fee, which makes the panel $289.
Both are HSA/FSA eligible.
Collection method: a lab visit or a kit at home
Empirical Health sends you to a lab, walk-in or booked same-day or next-day. Draws run at a national lab network, and a different partner serves New York and New Jersey.
Rythm collects at home, with no lab visit. The device takes a capillary sample into the same tubes clinics use, and the lab processes it. Collection is self-administered.
For someone who dislikes lab waiting rooms, Rythm removes the errand. For someone who wants a venous draw, Empirical keeps it.
Prescriptions and next steps
Empirical Health ties prescriptions to the doctor visit in its $399 program, where the doctor reviews results and discusses a care plan, prescriptions, or referrals.
Rythm says it does not prescribe, and its FAQ points members to their own doctor. Guidance comes from dashboard insights and the AI Coach, including supplement and dietary suggestions in the app. Members can share results by PDF, CSV, or link.
Rythm includes a biological age score, which unlocks after the second test. Empirical Health does not offer one.
Get 100+ biomarkers tested, in-lab or at home
One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.
Get 100+ biomarkers tested, in-lab or at home
One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.
Testing cadence and results speed
Rythm recommends testing every month, and suggests at least three tests before skipping, to establish a baseline. Empirical suggests testing annually at minimum, and every 3 to 6 months for anyone actively changing habits.
Rythm's results are quicker once the sample reaches the lab. It reports results within 2 days of the sample reaching the lab, a pace that comes with its much smaller panel, and kits take 2-3 business days to arrive. Empirical's results take 3-5 business days for most markers, and the full set takes 2-3 weeks.
Where are Empirical Health and Rythm tests available?
Rythm is available in all 50 states, to any U.S. address FedEx can reach. Empirical Health lists 2,200+ testing sites, though its medical services cover people in over 30 states.
Who is Empirical Health best for, and who is Rythm best for?
Empirical Health is best for:
- People who want heart-specific markers such as ApoB and Lp(a) in one draw.
- People who want a physician report, and a doctor visit for prescriptions.
- People who prefer a single draw to a monthly subscription.
Rythm is best for:
- People who want to test at home, every month, without a lab visit.
- People who value fast turnaround once the lab has the sample.
- People who want a biological age score and an AI Coach.
The bottom line
Empirical Health is built for people who want one deep heart read and a doctor to take it further. Rythm is built for people who want a small panel on a monthly rhythm, collected at home.
Both stop at the panel and the plan. Empirical's $190 buys one draw, with prescriptions reserved for the $399 program. Rythm's $79 kits come with suggestions in the app, no prescriptions, and no add-on tests yet.
Superpower costs $199 a year in most states, set against Empirical's $190 one-time panel and the $948 that 12 Rythm kits add up to before shipping and tax. Rythm samples monthly where Superpower draws once. One draw of 100+ biomarkers, your wearable data, and your medical records all feed one Superpower AI, which builds your Superpower Protocol and coaches you as readings arrive. Supplements at up to 20% off sit in the marketplace beside add-on tests and scans. Prescriptions are available there when clinically appropriate, priced separately. Superpower says 93% of members found their action plan more useful, even life-changing, than a yearly checkup.
Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.
Frequently asked questions
References
- Empirical Health. (2026). Home. Empirical Health.
- Empirical Health. (2026). Frequently asked questions. Empirical Health.
- Empirical Health. (2026). Advanced Heart Health program. Empirical Health.
- Empirical Health. (2026). Testing locations. Empirical Health.
- Rythm. (2026). Home. Rythm.
- Rythm. (2026). Product. Rythm.
- Rythm. (2026). Biomarkers. Rythm.
- Rythm. (2026). Frequently asked questions. Rythm.
- Rythm. (2026). Where Rythm is available. Rythm.



















