Empirical Health vs Rythm

Published

Last updated

Empirical Health
Rythm
Superpower Logo
Annual baseline test
100+ biomarkers on a single draw*
25+ biomarkers per monthly kit*
100+ biomarkers in one draw*
Cost
$190 one-time panel, or $399 for the 12-month Advanced program
$79/month plus shipping and tax
$199/year
Testing locations
2,000+ partner labs, walk-in or booked
At-home kit with free pick-up, all 50 states
2,000+ partner labs or at-home draw (+$119)
New York and New Jersey access
$99 lab fee added ($289 total)
Available, with a New York approved lab
+$200 to cover state fees
Follow-up test
Repeat testing at 3 and 9 months, $399 Advanced program only
A new kit each month by default, skippable for up to 90 days
Not included
Clinician access
Physician-interpreted report; doctor video visit in the $399 program
Physician sign-off before release; guidance from an AI Coach
AI and care team support on demand, year-round
Prescriptions
Through the doctor visit in the $399 Advanced program
Not included
Through the marketplace, when clinically appropriate, priced separately
Access to peptides
Not included
Not included
Results speed
Most results in 3-5 business days
Within 2 days of the sample reaching the lab
Within 10 days of the draw
Biological age tracking
Not included
Start testing

*Empirical Health's 100+ counts 85 lab results from one draw, alongside two heart-attack risk estimates, nine dietary metrics, and four app scores. Rythm's 25+ is its homepage figure per kit, with separate panels for men and women. Comparison based on publicly available information as of October 30, 2026.

Key takeaway:

Empirical Health ($190 one-time) pairs a one-visit lab draw of 100+ biomarkers with a physician-interpreted report on your heart. Rythm ($79/mo) is an at-home blood test, mailed monthly, that returns 25+ biomarkers from a capillary sample. If you want more than a single heart panel or a stream of small kits, Superpower ($199/yr) goes beyond biomarker testing to be a true home for health. Its one draw reads 100+ biomarkers, and the marketplace adds supplements and add-on tests, with compounded prescriptions (like peptides) available when clinically appropriate, priced separately. Superpower AI writes the plan from your data.
Read more →

What is Empirical Health, and what is Rythm?

Empirical Health is a heart-focused panel with a doctor attached. You visit a lab once, and a physician-interpreted report arrives with your risk scores.

Rythm calls itself "the world's easiest blood test." A kit arrives at your door each month, you collect a sample at home, and results follow in the app.

They differ most on where the blood is drawn, and on how often.

What does Empirical Health include?

The $190 panel includes 100+ biomarkers from one lab visit, heart risk scores in the app, and Empirical Pro for tracking trends.

Empirical describes its approach in three steps:

  1. Measure — Track 100+ biomarkers, including ApoB and Lp(a), at one of 2,200 testing sites.
  2. Predict — Estimate how your lifetime risk of heart disease responds to lifestyle changes.
  3. Prevent — Follow a custom nutrition plan and exercise routine built from your numbers.

Most results arrive within 3-5 business days. The $399 Advanced program stretches the offer across 12 months. Two retests, at 3 and 9 months, come with it, along with a video appointment with a board-certified doctor.

Join 150,000+ others building better health

Get the science behind better health, every week.

By clicking “Subscribe” you agree to our Terms of Service and Privacy Policy.

What does Rythm include?

Rythm is a monthly subscription at $79 a test. Each kit comes with free pick-up, biomarker explanations, an AI Coach with no usage limit, and a Rythm Score once your first test is complete.

Rythm's homepage lists three steps:

  1. At-Home Test — Collect a small capillary sample at home with a Tasso+ device.
  2. Send — Mail the sample back, or use the complimentary FedEx pick-up.
  3. Results — Receive them within 2 days of the sample reaching the lab.

The lab is Rythm's own, CLIA-certified and CAP-accredited. Before results are released, a state-licensed physician signs off. That is a lab release step and does not put a physician on call.

What biomarkers do Empirical Health and Rythm measure in 2026?

A single Empirical draw measures far more markers than a single Rythm kit, and Rythm repeats its kit up to twelve times a year. Empirical's count includes 26 urine items, while Rythm's list carries no urinalysis.

Empirical HealthRythm
Initial draw85 lab biomarkers (72 distinct and 13 calculated)27-28 biomarkers (21-22 distinct and 6 calculated)
Follow-up drawRepeat testing at 3 and 9 months, Advanced program onlyA new kit each month by default
Headline count100+ biomarkers on one draw25+ biomarkers per kit

Rythm's published list names 30 biomarkers across six categories, split into separate men's and women's panels because one collection limits how many markers fit.

Beyond the base panels, the two differ:

  • Empirical Health — The Advanced program adds repeat testing and the doctor visit.
  • Rythm — No add-on tests yet, with an add-on option on its roadmap.

What are the official 2026 membership prices for Empirical Health and Rythm?

Empirical Health costs $190 once, or $399 for the Advanced program. Rythm costs $79 a month, plus shipping and tax. Twelve kits at $79 come to $948 before shipping and tax.

Rythm renews every 30 days. Members can skip up to 90 days without being charged, and first-test discounts change from page to page. A 90-day money-back guarantee applies to first-time purchases.

Residents of New York and New Jersey pay Empirical an extra $99 lab fee, which makes the panel $289.

Both are HSA/FSA eligible.

Collection method: a lab visit or a kit at home

Empirical Health sends you to a lab, walk-in or booked same-day or next-day. Draws run at a national lab network, and a different partner serves New York and New Jersey.

Rythm collects at home, with no lab visit. The device takes a capillary sample into the same tubes clinics use, and the lab processes it. Collection is self-administered.

For someone who dislikes lab waiting rooms, Rythm removes the errand. For someone who wants a venous draw, Empirical keeps it.

Prescriptions and next steps

Empirical Health ties prescriptions to the doctor visit in its $399 program, where the doctor reviews results and discusses a care plan, prescriptions, or referrals.

Rythm says it does not prescribe, and its FAQ points members to their own doctor. Guidance comes from dashboard insights and the AI Coach, including supplement and dietary suggestions in the app. Members can share results by PDF, CSV, or link.

Rythm includes a biological age score, which unlocks after the second test. Empirical Health does not offer one.

Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

Book your test

Testing cadence and results speed

Rythm recommends testing every month, and suggests at least three tests before skipping, to establish a baseline. Empirical suggests testing annually at minimum, and every 3 to 6 months for anyone actively changing habits.

Rythm's results are quicker once the sample reaches the lab. It reports results within 2 days of the sample reaching the lab, a pace that comes with its much smaller panel, and kits take 2-3 business days to arrive. Empirical's results take 3-5 business days for most markers, and the full set takes 2-3 weeks.

Where are Empirical Health and Rythm tests available?

Rythm is available in all 50 states, to any U.S. address FedEx can reach. Empirical Health lists 2,200+ testing sites, though its medical services cover people in over 30 states.

Who is Empirical Health best for, and who is Rythm best for?

Empirical Health is best for:

  • People who want heart-specific markers such as ApoB and Lp(a) in one draw.
  • People who want a physician report, and a doctor visit for prescriptions.
  • People who prefer a single draw to a monthly subscription.

Rythm is best for:

  • People who want to test at home, every month, without a lab visit.
  • People who value fast turnaround once the lab has the sample.
  • People who want a biological age score and an AI Coach.

The bottom line

Empirical Health is built for people who want one deep heart read and a doctor to take it further. Rythm is built for people who want a small panel on a monthly rhythm, collected at home.

Both stop at the panel and the plan. Empirical's $190 buys one draw, with prescriptions reserved for the $399 program. Rythm's $79 kits come with suggestions in the app, no prescriptions, and no add-on tests yet.

Superpower costs $199 a year in most states, set against Empirical's $190 one-time panel and the $948 that 12 Rythm kits add up to before shipping and tax. Rythm samples monthly where Superpower draws once. One draw of 100+ biomarkers, your wearable data, and your medical records all feed one Superpower AI, which builds your Superpower Protocol and coaches you as readings arrive. Supplements at up to 20% off sit in the marketplace beside add-on tests and scans. Prescriptions are available there when clinically appropriate, priced separately. Superpower says 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.

Frequently asked questions

References

  1. Empirical Health. (2026). Home. Empirical Health.
  2. Empirical Health. (2026). Frequently asked questions. Empirical Health.
  3. Empirical Health. (2026). Advanced Heart Health program. Empirical Health.
  4. Empirical Health. (2026). Testing locations. Empirical Health.
  5. Rythm. (2026). Home. Rythm.
  6. Rythm. (2026). Product. Rythm.
  7. Rythm. (2026). Biomarkers. Rythm.
  8. Rythm. (2026). Frequently asked questions. Rythm.
  9. Rythm. (2026). Where Rythm is available. Rythm.

Put your health in trusted hands

  • Harvard Medical School
  • University of Chicago Pritzker School of Medicine
  • UCLA
  • Tufts School of Medicine
Dr. Anant Vinjamoori

Dr. Anant Vinjamoori, MD

Chief Longevity Officer, Superpower

Dr. Leigh Erin Connealy

Dr. Leigh Erin Connealy, MD

Clinician & Founder of The Centre for New Medicine

Dr. Abe Malkin

Dr. Abe Malkin, MD

Founder & Medical Director of Concierge MD

Dr. Robert Lufkin

Dr. Robert Lufkin, MD

Physician & UCLA Medical School Professor, NYT bestselling author

Transforming 150,000+ lives and counting

Camelia, 29

Camelia, 29

“I left the appointment feeling like I was being dramatic. I wasn't being dramatic. I was being responsible.”

Doctors refused to test her fertility, so she took control of her health

Thach, 37

Thach, 37

“They told me I was overthinking my genetic risk of diabetes but when I tested with Superpower I found my A1c was really high.”

His Superpower test caught diabetes risk that two doctors missed

Carissa, 38

Carissa, 38

“I spent almost a year thinking something was wrong with me. Turns out a simple blood test could have told me in a week.”

Uncovered the hormone imbalances behind bloating and weight gain

Teva, 28 and Cole, 29

Teva, 28 and Cole, 29

“I got my boyfriend a Superpower blood test. And it opened his eyes to things that seriously needed to change.”

The gift that changed how they think and talk about health

Ron, 53

Ron, 53

“I was putting in so much effort to improve my health. But nothing was working, until I got testing that actually showed me what to focus on.”

Superpower gave him a supplement plan that saved him time and money

1 / 5
Biological age 32 — a Superpower member portraitA health system built around you — test, understand, optimize100+ biomarkers across 2 blood drawsWhat to expect with Superpower — week 1 to month 3Trusted by 64,000+ customers — member reviewsBetter than the status quo — Superpower vs the old way60% of members found something a doctor missed — member survey
Daniel OSuperpower memberDavid LSuperpower memberRachel DSuperpower memberCamelia VSuperpower member

4.6 · 64,000+ members

Superpower health membership

Find early signs of 1,000+ conditions from a single blood draw - then act on what you find.

$199

/year*

100+ biomarkers from a single blood draw

Personalized plan that turns results into action

Superpower AI and on-demand care team

Results in 10 days or less

At-home or 2,000+ labs nationwide**

Yearly membership$0.55 / dayHSA/FSA eligible

*Pricing may vary for members in New York and New Jersey

**At-home labs for an additional cost

What we test

TestosteroneFree T4Vitamin DApoBHbA1cThyroid (TSH)hs-CRPFerritinCortisolFasting insulin

60%

found something a doctor missed

93%

rated it more useful than their checkup

77%

found something new in their results

Superpower member survey, 90 days post action plan (n=143).

How does the Superpower membership work?

We test 100+ biomarkers from a single blood draw each year. Your baseline test paints a comprehensive picture of your health, and your dashboard shows what’s working, what needs attention, and what to do next. Superpower AI and your care team help you take action across lifestyle, supplements, and treatments.

Can I cancel anytime?

Yes. You can cancel anytime, no fees. Your membership stays active through the end of your paid year.

How often should I test?

Your membership includes two blood tests per year: one to establish your baseline, and one to see whether your plan improved biomarkers that were out of range or not yet optimized. You can add other diagnostics anytime through the app or with help from your care team.

When will I get my results?

Book your draw at any of 2,000+ partner labs or at-home. Results are typically ready in about a week and land in the Superpower app.