Extended Metabolic Bundle

$99+$349 membership
New York / New Jersey

An add-on testing hormones and markers (insulin, C-peptide, fructosamine, leptin, and adiponectin) that go further than standard glucose and HbA1c.

See details →

Test details

Sample type:
Single blood draw (blood only)
Location:
In-person at local lab / At-home phlebotomist visit (+$119)
Availability:
Available in 40 states
Turnaround:
Most results are ready within 10 days

About the Extended Metabolic Bundle

This add-on layers extra metabolic markers onto your Baseline Blood Panel. Your metabolism is not one thing. It is a system of hormones and signals that determine how your body handles energy: how efficiently you burn fat, how you respond to food, and whether your blood sugar stays stable or swings unpredictably through the day.

Standard metabolic panels check blood sugar and maybe HbA1c. This add-on goes deeper, measuring the hormonal layer that regulates fat storage, appetite, and insulin sensitivity. These markers often shift years before changes appear on standard blood sugar tests.

1 in 3 U.S. adults has metabolic syndrome. Most don't know it, because the early signals don't show up on standard tests.

These markers map how your body regulates blood sugar, produces insulin, and signals hunger and fat storage: the system upstream of where standard blood work looks.

What standard blood sugar tests don't show

HbA1c measures your average blood glucose over the past three months. Fasting glucose gives a snapshot of blood sugar on a single morning. Both are useful core markers, and both measure the end result of a process that may have been developing long before it shows up.

Insulin resistance often begins with the pancreas overproducing insulin to compensate for cells that are becoming less responsive to it. Blood glucose can stay normal during this phase because the pancreas is working harder to keep it there. HbA1c and fasting glucose will not flag this compensated phase. Fasting insulin and C-peptide can.

Leptin and adiponectin add another dimension: how your fat tissue is functioning as a signaling organ. Adipose tissue is not passive storage. It secretes hormones that affect insulin sensitivity, inflammation, and appetite regulation. When these adipokine levels shift, they can reflect metabolic stress that standard glucose tests will not capture.

What this add-on measures

A single blood draw adds incremental metabolic markers on top of your Baseline Blood Panel.

Health categoryWhat this area coversMarkers (this add-on)
Metabolic HealthPancreatic insulin output and recent vs. compensated blood-sugar dynamics standard glucose tests missInsulin, C-Peptide, Fructosamine
Metabolic Health (adipose signaling)Fat tissue as a signaling organ: appetite and insulin-sensitivity hormonesLeptin, Adiponectin

Who benefits from testing

  • You have risk factors associated with metabolic syndrome or prediabetes (such as excess abdominal weight, elevated triglycerides, low HDL, or elevated blood pressure) and want a deeper read on your insulin status.
  • You have symptoms associated with insulin resistance, even though your fasting glucose and HbA1c are in the normal range. These symptoms include fatigue after meals, difficulty losing weight, strong carbohydrate cravings, or energy crashes.
  • You have been told you have PCOS, where insulin resistance is highly prevalent and a key factor in hormonal dysregulation.
  • You have a family history of type 2 diabetes or metabolic syndrome and want to understand your metabolic trajectory earlier rather than later.
  • Your body seems to handle food and energy differently than it used to, and you want to understand why.
  • You are actively trying to lose weight without success and want to understand whether leptin resistance or elevated insulin may be contributing.
  • You track your health proactively and want a metabolic baseline that goes beyond standard glucose testing.

No doctor's visit required. Add it to your Superpower order directly.

What your results reveal

Whether your metabolism is working with you or against you, and where your markers may indicate something to look into. If a hormone marker is shifted, you'll see which one. If insulin resistance is developing, you may detect early signs of it well before it would surface on standard glucose tests. This changes your approach from generic advice to targeted action.

Your results show a measured level for each marker, alongside reference ranges, so you can see at a glance which are within range and which are elevated or suppressed. Because your Baseline panel measures fasting glucose, a HOMA-IR insulin-resistance index can be calculated when both your fasting insulin and fasting glucose values are present, an index associated with insulin resistance rather than a diagnosis of it.

Your Superpower care team and AI-powered concierge can help you interpret the full picture, including how your insulin dynamics relate to the glucose, lipid, and inflammatory markers in the rest of your panel, and translate each result into plain-language next steps.

Reference ranges vary by lab and individual. Your Superpower care team and your provider will interpret your specific result in context.

How it works

  1. Add to your Superpower order. The Extended Metabolic Bundle layers onto your Baseline Blood Panel. No doctor's visit required.
  2. Get your blood drawn. At a local clinic near you, or with an optional at-home phlebotomist visit (+$119).
  3. Review your results in your Superpower dashboard, alongside your full panel data, with your care team or AI-powered concierge available to walk you through them. Most results are ready within 10 days.

Frequently asked questions

Biomarkers tested

Adiponectin is a protein hormone (also called an adipokine) that is mainly secreted by fat cells, but it is also produced in smaller amounts by muscle and the lining of blood vessels.

Learn more

Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.

Led by doctors with 40 years of health and longevity expertise

Dr. Anant Vinjamoori

Dr. Anant Vinjamoori, MD

Chief Longevity Officer, Superpower

Dr. Leigh Erin Connealy

Dr. Leigh Erin Connealy, MD

Clinician & Founder of The Centre for New Medicine

Dr. Robert Lufkin

Dr. Robert Lufkin, MD

Physician & UCLA Medical School Professor, NYT bestselling author

Dr. Abe Malkin

Dr. Abe Malkin, MD

Founder & Medical Director of Concierge MD

Biological age 32 — a Superpower member portraitA health system built around you — test, understand, optimize150+ biomarkers across 2 blood drawsWhat to expect with Superpower — week 1 to month 3Trusted by 64,000+ customers — member reviewsBetter than the status quo — Superpower vs the old way60% of members found something a doctor missed — member survey
Daniel OSuperpower memberDavid LSuperpower memberRachel DSuperpower memberCamelia VSuperpower member

4.6 · 64,000+ members

Superpower health membership

Find early signs of 1,000+ conditions - then act, retest, and see what changed.

$349

/year*

150+ biomarkers annually across baseline + retest

Personalized plan that turns results into action

Superpower AI and on-demand care team

Results in 10 days or less

At-home or 2,000+ labs nationwide**

Yearly membership$0.96 / dayHSA/FSA eligible

*Pricing may vary for members in New York and New Jersey

**At-home labs for an additional cost

What we test

TestosteroneFree T4Vitamin DApoBHbA1cThyroid (TSH)hs-CRPFerritinCortisolFasting insulin

60%

found something a doctor missed

93%

rated it more useful than their checkup

77%

found something new in their results

Superpower member survey, 90 days post action plan (n=143).

How does the Superpower membership work?

We test 150+ biomarkers annually across two blood draws. Your baseline test paints a comprehensive picture of your health, and your dashboard shows what’s working, what needs attention, and what to do next. Superpower AI and your care team help you take action across lifestyle, supplements, and treatments. Then we retest to track your progress and continue refining your plan.

Can I cancel anytime?

Yes. You can cancel anytime, no fees. Your membership stays active through the end of your paid year.

How often should I test?

Your membership includes two blood tests per year: one to establish your baseline, and one to see whether your plan improved biomarkers that were out of range or not yet optimized. You can add other diagnostics anytime through the app or with help from your care team.

When will I get my results?

Book your draw at any of 2,000+ partner labs or at-home. Results are typically ready in about a week and land in the Superpower app.

What the 100+ panel measures

All 101 markers in your annual baseline draw, organized by system. Nothing here is an upsell.

Heart & Vascular Health

26

  • Apolipoprotein B
  • Atherogenic Coefficient
  • Atherogenic Index of Plasma
  • Castelli Risk Index I
  • Castelli Risk Index II
  • HDL Cholesterol
  • LDL Cholesterol
  • LDL/HDL Ratio
  • Cholesterol, Total
  • Non-HDL Cholesterol
  • Cholesterol/HDL Ratio
  • Carbon Dioxide, Total
  • High-sensitivity CRP
  • hsCRP-to-Albumin Ratio (CAR)
  • GGT-to-HDL Cholesterol Ratio
  • LDL-C to Apolipoprotein B Ratio (LDL-C/ApoB)
  • LDL Cholesterol / Total Cholesterol (Mass Ratio)
  • Monocyte-to-HDL Ratio (MHR)
  • Neutrophil-to-HDL Cholesterol Ratio (NHR)
  • Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB)
  • NON-HDL Total Cholesterol Ratio
  • Triglyceride HDL Molar Ratio
  • Triglycerides
  • Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB)
  • TyG Index
  • Uric Acid

Metabolic Health

4

  • Estim. Avg Glu (eAG)
  • Eag (mmol/l)
  • Glucose
  • Hemoglobin A1c

Energy

1

  • Cortisol

Liver Health

15

  • Albumin/Globulin Ratio
  • Albumin
  • Alkaline Phosphatase (ALP)
  • Alanine Aminotransferase (ALT)
  • Aspartate Aminotransferase (AST)
  • Bilirubin Direct
  • Bilirubin Indirect
  • Bilirubin, Total
  • Bilirubin-to-Albumin Ratio
  • Ferritin
  • Ferritin-to-Albumin Ratio
  • y-Glutamyl Transferase (GGT)
  • Globulin, Total
  • Indirect-to-Direct Bilirubin Ratio
  • Protein, Total

Kidney

11

  • Calcium
  • Chloride
  • Corrected Calcium (Albumin-adjusted)
  • Creatinine
  • Estimated Glomerular Filtration Rate (eGFR)
  • Potassium
  • Sodium
  • BUN/Creatinine Ratio
  • Blood Urea Nitrogen (BUN)
  • Urea-to-Creatinine Ratio
  • Uric Acid-to-HDL Cholesterol Ratio (UHR)

Sex Hormones

7

  • DHEA-Sulfate (DHEA-S)
  • Free Androgen Index
  • Sex Hormone Binding Globulin (SHBG)
  • Free Testosterone
  • Testosterone, Bioavailable
  • Testosterone, Total
  • Testosterone-to-Estradiol Ratio (T/E₂)

Thyroid Health

4

  • Free Thyroxine Index
  • T3 Uptake
  • T4 (thyroxine) Total
  • Thyroid-Stimulating Hormone (TSH)

Nutrients

13

  • Vitamin D
  • Red Cell Dist Width (RDW)
  • Hematocrit
  • Hemoglobin
  • Total Iron Binding Capacity (TIBC)
  • Iron
  • Iron Saturation
  • Mean Cell Hemoglobin (MCH)
  • Mean Corpuscular Hemoglobin Concentration (MCHC)
  • Mean Cell Volume (MCV)
  • Platelet-to-WBC Ratio (PWR)
  • Red Blood Cells
  • RDW MCV Ratio

Immune System

12

  • Basophils
  • Baso (Absolute)
  • Eosinophils
  • Eos (Absolute)
  • Lymphocytes
  • Lymphs (Absolute)
  • Monocytes
  • Monocytes (Absolute)
  • Neutrophils
  • Neutrophils (Absolute)
  • Mean Platelet Volume
  • Platelet Count

Inflammation

8

  • Lymphocyte-to-Monocyte Ratio (LMR)
  • Monocyte-to-Lymphocyte Ratio (MLR)
  • Neutrophil-to-Lymphocyte-Platelet Ratio (NLPR)
  • Neutrophil-to-Lymphocyte Ratio (NLR)
  • Platelet-to-Lymphocyte Ratio (PLR)
  • Systemic Immune-Inflammation Index
  • Systemic Inflammation Response Index (SIRI)
  • White Blood Cells
Get my health baseline

The full list of 100+ markers and 8 specialty add-ons available at superpower.com/biomarkers.

Extended Metabolic BundleSchedule your test today