.svg)
Method: GC-MS (Gas Chromatography/Mass Spectrometry) measuring organic acid metabolites in urine (CLIA 17D0919496); not cleared or approved by the FDA. Results in mmol/mol creatinine. Not a stand-alone diagnosis; should be interpreted in clinical context.
3-Methyl-2-oxovaleric acid comes from isoleucine breakdown, the third of the branched-chain amino acids, with processing depending on B vitamins including thiamine (B1).
