Key Benefits

• See your inflammation-to-anabolic balance in a single, actionable number.
• Detect hidden, low-grade inflammation that blunts energy, performance, and mood.
• Personalize training load, recovery strategies, and nutrition choices.
• Guide weight, glucose, and lipid goals through an inflammation-aware lens.
• Track “inflammaging” and biological resilience as you age.
• Link inflammation status to adrenal and androgen health for both males and females.
• Prioritize sleep, stress, and recovery practices with objective feedback.
• Flag patterns that may point to underlying inflammation sources.
• Monitor response to anti-inflammatory, exercise, and lifestyle interventions.
• Complement hs-CRP and DHEA-S with a ratio that sharpens decision-making.

What is CRP / DHEA-S Ratio?

CRP is an acute-phase protein released by the liver in response to inflammation. High-sensitivity CRP (hs-CRP) detects even low-grade, chronic inflammatory activity. DHEA-S is a stable adrenal androgen with immunomodulatory and anti-catabolic properties.

The CRP / DHEA-S Ratio is calculated by dividing hs-CRP by DHEA-S, producing a single marker of inflammatory load relative to anabolic reserve. Males usually have higher DHEA-S than females, so sex and age matter in interpretation.

Why is CRP / DHEA-S Ratio Biomarker Testing Important?

Single markers tell only part of the story. The ratio integrates two biological axes—immune activation and anabolic resilience—explaining why fatigue, slow recovery, or plateaued progress may persist.

Research links higher ratios to greater cardiometabolic risk, frailty, and chronic disease burden, while lower ratios align with better recovery and resilience. Tracking trends sharpens decisions on training, body composition, and anti-inflammatory nutrition.

What Insights Will I Get?

Male

• Low ratio: Very favorable balance, strong recovery potential and resilience.
• Optimal ratio: Balanced inflammation control with robust recovery capacity.
• High ratio: Indicates disproportionate inflammatory load and reduced resilience; prioritize anti-inflammatory nutrition, weight control, and restorative sleep.

Female

• Low ratio: Favorable balance, efficient recovery, and stable energy.
• Optimal ratio: Balanced inflammation control with age-appropriate DHEA-S.
• High ratio: Suggests higher inflammatory burden with lower DHEA-S reserve; focus on fiber-rich nutrition, structured training, and stress management.

CRP / DHEA-S Ratio and Your Health

Your ratio links everyday choices to deeper biology. Anti-inflammatory eating, adequate protein, high-fiber plants, omega-3s, and reduced ultra-processed foods improve balance. Strength training, aerobic conditioning, and structured recovery support both lower CRP and stronger DHEA-S.

Sleep quality, stress reduction, oral health, and body composition also matter. Persistent high ratios may point to drivers such as excess weight, gum disease, chronic infections, autoimmunity, or environmental exposures. Retesting every 8–12 weeks shows progress and sharpens next steps.

‍